Bernstein, Paul S.

A Variant of the HTRA1 Gene Increases Susceptibility to Age-Related Macular Degeneration

Yang, Z., Camp, N. J., Sun, H., Tong, Z., Gibbs, D., Cameron, D. J., Chen, H., Zhao, Y., Pearson, E., Li, X., et al. (2006) · Science

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 796

Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials

Heier, J. S., Lad, E. M., Holz, F. G., Rosenfeld, P. J., Guymer, R. H., Boyer, D., Grossi, F., Baumal, C. R., Korobelnik, J.-F., Slakter, J. S., et al. (2023) · The Lancet

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 520

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene ( LIPC )

Neale, B. M., Fagerness, J., Reynolds, R., Sobrin, L., Parker, M., Raychaudhuri, S., Tan, P. L., Oh, E. C., Merriam, J. E., Souied, E., et al. (2010) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 442

Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression: AREDS2 Report No. 3

Chew, E. Y., Clemons, T. E., SanGiovanni, J. P., Danis, R. P., Ferris, F. L., Elman, M. J., Antoszyk, A. N., Ruby, A. J., Orth, D., Bressler, S. B., et al. (2014) · JAMA Ophthalmology

Retinal Diseases and TreatmentsAntioxidant Activity and Oxidative Stress

Cited by 415

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD

Magnusson, K. P., Duan, S., Sigurdsson, H., Petursson, H., Yang, Z., Zhao, Y., Bernstein, P. S., Ge, J., Jonasson, F., Stefansson, E., et al. (2005) · PLoS Medicine

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 226

Toll-like Receptor 3 and Geographic Atrophy in Age-Related Macular Degeneration

Yang, Z., Stratton, C., Francis, P. J., Kleinman, M. E., Tan, P. L., Gibbs, D., Tong, Z., Chen, H., Constantine, R., Yang, X., et al. (2008) · New England Journal of Medicine

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 222

Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies

Hatori, M., Gronfier, C., Van Gelder, R. N., Bernstein, P. S., Carreras, J., Panda, S., Marks, F., Sliney, D., Hunt, C. E., Hirota, T., et al. (2017) · npj Aging and Mechanisms of Disease

Circadian rhythm and melatoninImpact of Light on Environment and Health

Cited by 212

Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial

Chew, E. Y., Clemons, T. E., Agrón, E., Launer, L. J., Grodstein, F., & Bernstein, P. S. (2015) · JAMA

Fatty Acid Research and HealthDementia and Cognitive Impairment Research

Cited by 191

Long-chain and very long-chain polyunsaturated fatty acids in ocular aging and age-related macular degeneration

Liu, A., Chang, J., Lin, Y., Shen, Z., & Bernstein, P. S. (2010) · Journal of Lipid Research

Retinal Diseases and TreatmentsFatty Acid Research and Health

Cited by 151

Shifting students and faculty to a PBL curriculum: attitudes changed and lessons learned

Bernstein, P., Tipping, J., Bercovitz, K., & Skinner, H. A. (1995) · Academic Medicine

Problem and Project Based LearningInnovations in Medical Education

Cited by 127

HTRA1 variant confers similar risks to geographic atrophy and neovascular age-related macular degeneration

Cameron, D. J., Yang, Z., Gibbs, D., Chen, H., Kaminoh, Y., Jorgensen, A., Zeng, J., Luo, L., Brinton, E., Brinton, G., et al. (2007) · Cell Cycle

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 114

Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium

Bhosale, P., Serban, B., & Bernstein, P. S. (2009) · Archives of Biochemistry and Biophysics

Retinal Diseases and TreatmentsAntioxidant Activity and Oxidative Stress

Cited by 85

ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration

Sobrin, L., Reynolds, R., Yu, Y., Fagerness, J., Leveziel, N., Bernstein, P. S., Souied, E. H., Daly, M. J., & Seddon, J. M. (2011) · American Journal of Ophthalmology

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 78

In vivo isomerization of all-trans- to 11-cis-retinoids in the eye occurs at the alcohol oxidation-state

Bernstein, P. S., & Rando, R. R. (1986) · Biochemistry

Retinoids in leukemia and cellular processesRetinal Development and Disorders

Cited by 65

Retinal bioavailability and functional effects of a synthetic very-long-chain polyunsaturated fatty acid in mice

Gorusupudi, A., Rallabandi, R., Li, B., Arunkumar, R., Blount, J. D., Rognon, G. T., Chang, F.-Y., Wade, A., Lucas, S., Conboy, J. C., et al. (2021) · Proceedings of the National Academy of Sciences

Fatty Acid Research and HealthRetinal Development and Disorders

Cited by 33

Influence of very-long-chain polyunsaturated fatty acids on membrane structure and dynamics

Cheng, V., Rallabandi, R., Gorusupudi, A., Lucas, S., Rognon, G., Bernstein, P. S., Rainier, J. D., & Conboy, J. C. (2022) · Biophysical Journal

Lipid Membrane Structure and BehaviorFatty Acid Research and Health

Cited by 14

Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function

Yang, Z.-H., Gorusupudi, A., Lydic, T. A., Mondal, A. K., Sato, S., Yamazaki, I., Yamaguchi, H., Tang, J., Rojulpote, K. V., Lin, A. B., et al. (2023) · iScience

Fatty Acid Research and HealthAquaculture Nutrition and Growth

Cited by 9