Koritzinsky, Marianne

Hypoxia signalling through mTOR and the unfolded protein response in cancer

Wouters, B. G., & Koritzinsky, M. (2008) · Nature Reviews Cancer

Cancer, Hypoxia, and MetabolismPI3K/AKT/mTOR signaling in cancer

Cited by 894

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

Rouschop, K. M. A., van den Beucken, T., Dubois, L., Niessen, H., Bussink, J., Savelkouls, K., Keulers, T., Mujcic, H., Landuyt, W., Voncken, J. W., et al. (2010) · Journal of Clinical Investigation

Autophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease

Cited by 829

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

Erler, J. T., Cawthorne, C. J., Williams, K. J., Koritzinsky, M., Wouters, B. G., Wilson, C., Miller, C., Demonacos, C., Stratford, I. J., & Dive, C. (2004) · Molecular and Cellular Biology

Cell death mechanisms and regulationCancer, Hypoxia, and Metabolism

Cited by 400

Two phases of disulfide bond formation have differing requirements for oxygen

Koritzinsky, M., Levitin, F., van den Beucken, T., Rumantir, R. A., Harding, N. J., Chu, K. C., Boutros, P. C., Braakman, I., & Wouters, B. G. (2013) · Journal of Cell Biology

Endoplasmic Reticulum Stress and DiseaseRedox biology and oxidative stress

Cited by 136

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs

Hunter, F. W., Young, R. J., Shalev, Z., Vellanki, R. N., Wang, J., Gu, Y., Joshi, N., Sreebhavan, S., Weinreb, I., Goldstein, D. P., et al. (2015) · Cancer Research

Cancer, Hypoxia, and MetabolismPharmacogenetics and Drug Metabolism

Cited by 82

MATE2 Expression Is Associated With Cancer Cell Response to Metformin

Chowdhury, S., Yung, E., Pintilie, M., Muaddi, H., Chaib, S., Yeung, M., Fusciello, M., Sykes, J., Pitcher, B., Hagenkort, A., et al. (2016) · PLoS ONE

Metabolism, Diabetes, and CancerDrug Transport and Resistance Mechanisms

Cited by 33

Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

Marastoni, S., Madariaga, A., Pesic, A., Nair, S. N., Li, Z. J., Shalev, Z., Ketela, T., Colombo, I., Mandilaras, V., Cabanero, M., et al. (2022) · Cancer Research Communications

Ovarian cancer diagnosis and treatmentAutophagy in Disease and Therapy

Cited by 19