Itan, Yuval

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Bastard, P., Rosen, L. B., Zhang, Q., Michailidis, E., Hoffmann, H.-H., Zhang, Y., Dorgham, K., Philippot, Q., Rosain, J., Béziat, V., et al. (2020) · Science

interferon and immune responsesSARS-CoV-2 and COVID-19 Research

Cited by 2,662

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Zhang, Q., Bastard, P., Liu, Z., Le Pen, J., Moncada-Velez, M., Chen, J., Ogishi, M., Sabli, I. K. D., Hodeib, S., Korol, C., et al. (2020) · Science

interferon and immune responsesSARS-CoV-2 and COVID-19 Research

Cited by 2,229

The Origins of Lactase Persistence in Europe

Itan, Y., Powell, A., Beaumont, M. A., Burger, J., & Thomas, M. G. (2009) · PLoS Computational Biology

Digestive system and related healthGenetic and phenotypic traits in livestock

Cited by 569

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

Zhang, X., Bogunovic, D., Payelle-Brogard, B., Francois-Newton, V., Speer, S. D., Yuan, C., Volpi, S., Li, Z., Sanal, O., Mansouri, D., et al. (2015) · Nature

interferon and immune responsesInflammasome and immune disorders

Cited by 558

Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

Okada, S., Markle, J. G., Deenick, E. K., Mele, F., Averbuch, D., Lagos, M., Alzahrani, M., Al-Muhsen, S., Halwani, R., Ma, C. S., et al. (2015) · Science

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 413

Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery

Greater Middle East Variome Consortium, Scott, E. M., Halees, A., Itan, Y., Spencer, E. G., He, Y., Azab, M. A., Gabriel, S. B., Belkadi, A., Boisson, B., et al. (2016) · Nature Genetics

Genomics and Rare DiseasesForensic and Genetic Research

Cited by 376

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes

Deschamps, M., Laval, G., Fagny, M., Itan, Y., Abel, L., Casanova, J.-L., Patin, E., & Quintana-Murci, L. (2016) · The American Journal of Human Genetics

Evolution and Genetic DynamicsGenetic Associations and Epidemiology

Cited by 257

Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections

Dobbs, K., Domínguez Conde, C., Zhang, S.-Y., Parolini, S., Audry, M., Chou, J., Haapaniemi, E., Keles, S., Bilic, I., Okada, S., et al. (2015) · New England Journal of Medicine

Immunodeficiency and Autoimmune DisordersBlood disorders and treatments

Cited by 201

Evolutionary genetic dissection of human interferons

Manry, J., Laval, G., Patin, E., Fornarino, S., Itan, Y., Fumagalli, M., Sironi, M., Tichit, M., Bouchier, C., Casanova, J.-L., et al. (2011) · Journal of Experimental Medicine

interferon and immune responsesEvolution and Genetic Dynamics

Cited by 176

Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature set

Stein, D., Sevim Bayrak, Ç., Wu, Y., Kars, M. E., Stenson, P. D., Cooper, D. N., Schlessinger, A., & Itan, Y. (2022) · Genome Medicine

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 53

Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature set

Stein, D., Kars, M. E., Wu, Y., Bayrak, Ç. S., Stenson, P. D., Cooper, D. N., Schlessinger, A., & Itan, Y. (2023) · Genome Medicine

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 53

Human CRY1 variants associate with attention deficit/hyperactivity disorder

Onat, O. E., Kars, M. E., Gül, Ş., Bilguvar, K., Wu, Y., Özhan, A., Aydın, C., Başak, A. N., Trusso, M. A., Goracci, A., et al. (2020) · Journal of Clinical Investigation

Circadian rhythm and melatoninAttention Deficit Hyperactivity Disorder

Cited by 47