Roden, Michael

Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects

Perseghin, G., Price, T. B., Petersen, K. F., Roden, M., Cline, G. W., Gerow, K., Rothman, D. L., & Shulman, G. I. (1996) · New England Journal of Medicine

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 699

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Suzuki, K., Hatzikotoulas, K., Southam, L., Taylor, H. J., Yin, X., Lorenz, K. M., Mandla, R., Huerta-Chagoya, A., Melloni, G. E. M., Kanoni, S., et al. (2024) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 606

The role of mitochondria in insulin resistance and type 2 diabetes mellitus

Szendroedi, J., Phielix, E., & Roden, M. (2012) · Nature Reviews Endocrinology

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 600

Thiazolidinediones, Like Metformin, Inhibit Respiratory Complex I

Brunmair, B., Staniek, K., Gras, F., Scharf, N., Althaym, A., Clara, R., Roden, M., Gnaiger, E., Nohl, H., Waldhäusl, W., et al. (2004) · Diabetes

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 521

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

Tremblay, F., Brûlé, S., Hee Um, S., Li, Y., Masuda, K., Roden, M., Sun, X. J., Krebs, M., Polakiewicz, R. D., Thomas, G., et al. (2007) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 465

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

Szendroedi, J., Yoshimura, T., Phielix, E., Koliaki, C., Marcucci, M., Zhang, D., Jelenik, T., Müller, J., Herder, C., Nowotny, P., et al. (2014) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 415

Impact of common genetic determinants of hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

Wheeler, E., Leong, A., Liu, C.-T., Hivert, M.-F., Strawbridge, R. J., Podmore, C., Li, M., Yao, J., Sim, X., Hong, J., et al. (2017) · PLOS Medicine

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 408

Mechanism of Amino Acid-Induced Skeletal Muscle Insulin Resistance in Humans

Krebs, M., Krssak, M., Bernroider, E., Anderwald, C., Brehm, A., Meyerspeer, M., Nowotny, P., Roth, E., Waldhäusl, W., & Roden, M. (2002) · Diabetes

Muscle metabolism and nutritionMetabolism, Diabetes, and Cancer

Cited by 392

Adverse effects of statin therapy: perception vs. the evidence – focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract

Mach, F., Ray, K. K., Wiklund, O., Corsini, A., Catapano, A. L., Bruckert, E., De Backer, G., Hegele, R. A., Hovingh, G. K., Jacobson, T. A., et al. (2018) · European Heart Journal

Lipoproteins and Cardiovascular HealthCancer, Lipids, and Metabolism

Cited by 370

Overactivation of S6 Kinase 1 as a Cause of Human Insulin Resistance During Increased Amino Acid Availability

Tremblay, F., Krebs, M., Dombrowski, L., Brehm, A., Bernroider, E., Roth, E., Nowotny, P., Waldhäusl, W., Marette, A., & Roden, M. (2005) · Diabetes

Muscle metabolism and nutritionMetabolism, Diabetes, and Cancer

Cited by 370

Empagliflozin effectively lowers liver fat content in well-controlled type 2 diabetes: a randomized, double-blind, phase 4, placebo-controlled trial

Kahl, S., Gancheva, S., Straßburger, K., Herder, C., Machann, J., Katsuyama, H., Kabisch, S., Henkel, E., Kopf, S., Lagerpusch, M., et al. (2020) · Diabetes Care

Diabetes Treatment and ManagementLiver Disease Diagnosis and Treatment

Cited by 360

Nonalcoholic fatty liver disease (NAFLD) from pathogenesis to treatment concepts in humans

Pafili, K., & Roden, M. (2021) · Molecular Metabolism

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 330

Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors

Francque, S., Szabo, G., Abdelmalek, M. F., Byrne, C. D., Cusi, K., Dufour, J.-F., Roden, M., Sacks, F., & Tacke, F. (2021) · Nature Reviews Gastroenterology & Hepatology

Liver Disease Diagnosis and TreatmentPeroxisome Proliferator-Activated Receptors

Cited by 316

Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes.

Krssak, M., Brehm, A., Bernroider, E., Anderwald, C., Nowotny, P., Man, C. D., Cobelli, C., Cline, G. W., Shulman, G. I., Waldhäusl, W., et al. (2004) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 313

Effects of free fatty acid elevation on postabsorptive endogenous glucose production and gluconeogenesis in humans

Roden, M., Stingl, H., Chandramouli, V, Schumann, W. C., Hofer, A., Landau, B. R., Nowotny, P., Waldhäusl, W., & Shulman, G. I. (2000) · Diabetes

Pancreatic function and diabetesDiet, Metabolism, and Disease

Cited by 288

Specific hepatic sphingolipids relate to insulin resistance, oxidative stress, and inflammation in nonalcoholic steatohepatitis

Apostolopoulou, M., Gordillo, R., Koliaki, C., Gancheva, S., Jelenik, T., De Filippo, E., Herder, C., Markgraf, D., Jankowiak, F., Esposito, I., et al. (2018) · Diabetes Care

Liver Disease Diagnosis and TreatmentSphingolipid Metabolism and Signaling

Cited by 284

Inter-organ crosstalk during development and progression of type 2 diabetes mellitus

Xourafa, G., Korbmacher, M., & Roden, M. (2024) · Nature Reviews Endocrinology

Adipokines, Inflammation, and Metabolic DiseasesPancreatic function and diabetes

Cited by 274

Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept

Simon, M.-C., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J.-H., Stehle, P., Pacini, G., et al. (2015) · Diabetes Care

Probiotics and Fermented FoodsGut microbiota and health

Cited by 253

Muscle Mitochondrial ATP Synthesis and Glucose Transport/Phosphorylation in Type 2 Diabetes

Szendroedi, J., Schmid, A. I., Chmelik, M., Toth, C., Brehm, A., Krssak, M., Nowotny, P., Wolzt, M., Waldhausl, W., & Roden, M. (2007) · PLoS Medicine

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 243

Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle

Brehm, A., Krssak, M., Schmid, A. I., Nowotny, P., Waldhäusl, W., & Roden, M. (2006) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 239

The Mammalian Target of Rapamycin Pathway Regulates Nutrient-Sensitive Glucose Uptake in Man

Krebs, M., Brunmair, B., Brehm, A., Artwohl, M., Szendroedi, J., Nowotny, P., Roth, E., Fürnsinn, C., Promintzer, M., Anderwald, C., et al. (2007) · Diabetes

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 230

Liver ATP Synthesis Is Lower and Relates to Insulin Sensitivity in Patients With Type 2 Diabetes

Schmid, A. I., Szendroedi, J., Chmelik, M., Krššák, M., Moser, E., & Roden, M. (2011) · Diabetes Care

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 212

Abnormal Hepatic Energy Homeostasis in Type 2 Diabetes†

Szendroedi, J., Chmelik, M., Schmid, A. I., Nowotny, P., Brehm, A., Krssak, M., Moser, E., & Roden, M. (2009) · Hepatology

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 204

Hepatic glucose metabolism in humans—its role in health and disease

Roden, M., & Bernroider, E. (2003) · Best Practice & Research Clinical Endocrinology & Metabolism

Diabetes Management and ResearchMetabolism, Diabetes, and Cancer

Cited by 201