Smith, Lloyd M.

Proteoform: a single term describing protein complexity

The Consortium for Top Down Proteomics, Smith, L. M., & Kelleher, N. L. (2013) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 1,528

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., et al. (2018) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 907

Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction

Hallows, W. C., Yu, W., Smith, B. C., Devires, M. K., Ellinger, J. J., Someya, S., Shortreed, M. R., Prolla, T., Markley, J. L., Smith, L. M., et al. (2011) · Molecular Cell

Sirtuins and Resveratrol in MedicineAutophagy in Disease and Therapy

Cited by 389

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

Donnelly, D. P., Rawlins, C. M., DeHart, C. J., Fornelli, L., Schachner, L. F., Lin, Z., Lippens, J. L., Aluri, K. C., Sarin, R., Chen, B., et al. (2019) · Nature Methods

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 377

Proteoforms as the next proteomics currency

Smith, L. M., & Kelleher, N. L. (2018) · Science

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 322

The Human Proteoform Project: Defining the human proteome

Smith, L. M., Agar, J. N., Chamot-Rooke, J., Danis, P. O., Ge, Y., Loo, J. A., Paša-Tolić, L., Tsybin, Y. O., Kelleher, N. L., & The Consortium for Top-Down Proteomics (2021) · Science Advances

Advanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and Applications

Cited by 242

Identification and Quantification of Proteoforms by Mass Spectrometry

Schaffer, L. V., Millikin, R. J., Miller, R. M., Anderson, L. C., Fellers, R. T., Ge, Y., Kelleher, N. L., LeDuc, R. D., Liu, X., Payne, S. H., et al. (2019) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 209

Top-down proteomics

Roberts, D. S., Loo, J. A., Tsybin, Y. O., Liu, X., Wu, S., Chamot-Rooke, J., Agar, J. N., Paša-Tolić, L., Smith, L. M., & Ge, Y. (2024) · Nature Reviews Methods Primers

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 161

Discovery and mass spectrometric analysis of novel splice-junction peptides using RNA-Seq

Sheynkman, G. M., Shortreed, M. R., Frey, B. L., & Smith, L. M. (2013) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsGenomics and Phylogenetic Studies

Cited by 128

α-Ketoisocaproate-Induced Hypersecretion of Insulin by Islets from Diabetes-Susceptible Mice

Rabaglia, M. E., Gray-Keller, M. P., Frey, B. L., Shortreed, M. R., Smith, L. M., & Attie, A. D. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 96

Putting humpty dumpty back together again: what does protein quantification mean in bottom-up proteomics?

Plubell, D. L., Käll, L., Webb-Robertson, B.-J., Bramer, L. M., Ives, A., Kelleher, N. L., Smith, L. M., Montine, T. J., Wu, C. C., & MacCoss, M. J. (2022) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsAdvanced Biosensing Techniques and Applications

Cited by 85

Elucidating Proteoform Families from Proteoform Intact-Mass and Lysine-Count Measurements

Shortreed, M. R., Frey, B. L., Scalf, M., Knoener, R. A., Cesnik, A. J., & Smith, L. M. (2016) · Journal of Proteome Research

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 58

Elucidating the in vivo interactome of HIV-1 RNA by hybridization capture and mass spectrometry

Knoener, R. A., Becker, J. T., Scalf, M., Sherer, N. M., & Smith, L. M. (2017) · Scientific Reports

HIV Research and TreatmentAdvanced Proteomics Techniques and Applications

Cited by 54

Intact-Mass Analysis Facilitating the Identification of Large Human Heart Proteoforms

Schaffer, L. V., Tucholski, T., Shortreed, M. R., Ge, Y., & Smith, L. M. (2019) · Analytical Chemistry

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 17

Back Cover: Identification and Quantification of Proteoforms by Mass Spectrometry

Schaffer, L. V., Millikin, R. J., Miller, R. M., Anderson, L. C., Fellers, R. T., Ge, Y., Kelleher, N. L., LeDuc, R. D., Liu, X., Payne, S. H., et al. (2019) · PROTEOMICS

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 9