Ting, Tabitha C.

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15

Han, T., Goralski, M., Gaskill, N., Capota, E., Kim, J., Ting, T. C., Xie, Y., Williams, N. S., & Nijhawan, D. (2017) · Science

RNA Research and SplicingUbiquitin and proteasome pathways

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Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice

Fernández, Á. F., Sebti, S., Wei, Y., Zou, Z., Shi, M., McMillan, K. L., He, C., Ting, T., Liu, Y., Chiang, W.-C., et al. (2018) · Nature

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

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A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease

Rocchi, A., Yamamoto, S., Ting, T., Fan, Y., Sadleir, K., Wang, Y., Zhang, W., Huang, S., Levine, B., Vassar, R., et al. (2017) · PLOS Genetics

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

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Aryl Sulfonamides Degrade RBM39 and RBM23 by Recruitment to CRL4-DCAF15

Ting, T. C., Goralski, M., Klein, K., Wang, B., Kim, J., Xie, Y., & Nijhawan, D. (2019) · Cell Reports

RNA Research and SplicingProtein Degradation and Inhibitors

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