Horowitz, Jeffrey C.

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

Liu, F., Lagares, D., Choi, K. M., Stopfer, L., Marinković, A., Vrbanac, V., Probst, C. K., Hiemer, S. E., Sisson, T. H., Horowitz, J. C., et al. (2015) · American Journal of Physiology-Lung Cellular and Molecular Physiology

Hippo pathway signaling and YAP/TAZInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 874

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

Hecker, L., Vittal, R., Jones, T., Jagirdar, R., Luckhardt, T. R., Horowitz, J. C., Pennathur, S., Martinez, F. J., & Thannickal, V. J. (2009) · Nature Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisRedox biology and oxidative stress

Cited by 852

Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation

Booth, A. J., Hadley, R., Cornett, A. M., Dreffs, A. A., Matthes, S. A., Tsui, J. L., Weiss, K., Horowitz, J. C., Fiore, V. F., Barker, T. H., et al. (2012) · American Journal of Respiratory and Critical Care Medicine

Tissue Engineering and Regenerative MedicineInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 665

Activation of the Pro-survival Phosphatidylinositol 3-Kinase/AKT Pathway by Transforming Growth Factor-β1 in Mesenchymal Cells Is Mediated by p38 MAPK-dependent Induction of an Autocrine Growth Factor

Horowitz, J. C., Lee, D. Y., Waghray, M., Keshamouni, V. G., Thomas, P. E., Zhang, H., Cui, Z., & Thannickal, V. J. (2004) · Journal of Biological Chemistry

TGF-β signaling in diseasesProtein Kinase Regulation and GTPase Signaling

Cited by 239

Prostaglandin E 2 induces fibroblast apoptosis by modulating multiple survival pathways

Huang, S. K., White, E. S., Wettlaufer, S. H., Grifka, H., Hogaboam, C. M., Thannickal, V. J., Horowitz, J. C., & Peters-Golden, M. (2009) · The FASEB Journal

Inflammatory mediators and NSAID effectsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 147

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health.

SenNet Consortium, Writing Group, Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., et al. (2022) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 122

Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts

Bai, L., Bernard, K., Tang, X., Hu, M., Horowitz, J. C., Thannickal, V. J., & Sanders, Y. Y. (2019) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisEpigenetics and DNA Methylation

Cited by 88

SMAD-Independent Down-Regulation of Caveolin-1 by TGF-β: Effects on Proliferation and Survival of Myofibroblasts

Sanders, Y. Y., Cui, Z., Le Saux, C. J., Horowitz, J. C., Rangarajan, S., Kurundkar, A., Antony, V. B., & Thannickal, V. J. (2015) · PLOS ONE

TGF-β signaling in diseasesCaveolin-1 and cellular processes

Cited by 49

Incidental Pulmonary Nodule Detection and Factors Influencing Follow-Up: A Retrospective Study in an Academic Medical Center

Pannu, J. K., Venious, G. J., Gallagher, R., Shaver, A. C., Cloyes, R., Josan, E. S., Donnelly, E., Stephens, J. A., Merritt, R. E., Pastis, N. J., et al. (2025) · CHEST Pulmonary

Lung Cancer Diagnosis and TreatmentMedical Imaging and Pathology Studies

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