Oshima, Masanobu

CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth

Ishimoto, T., Nagano, O., Yae, T., Tamada, M., Motohara, T., Oshima, H., Oshima, M., Ikeda, T., Asaba, R., Yagi, H., et al. (2011) · Cancer Cell

Redox biology and oxidative stressSulfur Compounds in Biology

Cited by 1,192

Early Embryonic Lethality Caused by Targeted Disruption of the Mouse Thioredoxin Gene

Matsui, M., Oshima, M., Oshima, H., Takaku, K., Maruyama, T., Yodoi, J., & Taketo, M. M. (1996) · Developmental Biology

Redox biology and oxidative stressDevelopmental Biology and Gene Regulation

Cited by 546

Gut microbiota promotes obesity-associated liver cancer through pge2-mediated suppression of antitumor immunity.

Loo, T. M., Kamachi, F., Watanabe, Y., Yoshimoto, S., Kanda, H., Arai, Y., Nakajima-Takagi, Y., Iwama, A., Koga, T., Sugimoto, Y., et al. (2017) · Cancer Discovery

Gut microbiota and healthHepatocellular Carcinoma Treatment and Prognosis

Cited by 478

CRISPR-Cas9–mediated gene knockout in intestinal tumor organoids provides functional validation for colorectal cancer driver genes

Takeda, H., Kataoka, S., Nakayama, M., Ali, M. A. E., Oshima, H., Yamamoto, D., Park, J.-W., Takegami, Y., An, T., Jenkins, N. A., et al. (2019) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringGenetic factors in colorectal cancer

Cited by 172

Combined Mutation of Apc, Kras , and Tgfbr2 Effectively Drives Metastasis of Intestinal Cancer

Sakai, E., Nakayama, M., Oshima, H., Kouyama, Y., Niida, A., Fujii, S., Ochiai, A., Nakayama, K. I., Mimori, K., Suzuki, Y., et al. (2018) · Cancer Research

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

Cited by 133

Chromosomal instability by β-catenin/TCF transcription in APC or β-catenin mutant cells

Aoki, K., Aoki, M., Sugai, M., Harada, N., Miyoshi, H., Tsukamoto, T., Mizoshita, T., Tatematsu, M., Seno, H., Chiba, T., et al. (2007) · Oncogene

Wnt/β-catenin signaling in development and cancerGenetic factors in colorectal cancer

Cited by 82

Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer

Miyata, K., Imai, Y., Hori, S., Nishio, M., Loo, T. M., Okada, R., Yang, L., Nakadai, T., Maruyama, R., Fujii, R., et al. (2021) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 74

A genome-scale CRISPR screen reveals factors regulating Wnt-dependent renewal of mouse gastric epithelial cells

Murakami, K., Terakado, Y., Saito, K., Jomen, Y., Takeda, H., Oshima, M., & Barker, N. (2021) · Proceedings of the National Academy of Sciences

Wnt/β-catenin signaling in development and cancerCRISPR and Genetic Engineering

Cited by 62

Clinical utility of a STAT3-regulated miRNA-200 family signature with prognostic potential in early gastric cancer

Yu, L., Wu, D., Gao, H., Balic, J. J., Tsykin, A., Han, T.-S., Liu, Y. D., Kennedy, C. L., Li, J. K., Mao, J. Q., et al. (2018) · Clinical Cancer Research

MicroRNA in disease regulationGastric Cancer Management and Outcomes

Cited by 50

RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells

Sugawara, S., Okada, R., Loo, T. M., Tanaka, H., Miyata, K., Chiba, M., Kawasaki, H., Katoh, K., Kaji, S., Maezawa, Y., et al. (2022) · Communications Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 23