Eischen, Christine M.

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., & Roussel, M. F. (1998) · Genes & Development

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

Cited by 1,245

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

Eischen, C. M., Weber, J. D., Roussel, M. F., Sherr, C. J., & Cleveland, J. L. (1999) · Genes & Development

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 819

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

Thomas, L. R., Wang, Q., Grieb, B. C., Phan, J., Foshage, A. M., Sun, Q., Olejniczak, E. T., Clark, T., Dey, S., Lorey, S., et al. (2015) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 310

Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides

McGirt, L. Y., Jia, P., Baerenwald, D. A., Duszynski, R. J., Dahlman, K. B., Zic, J. A., Zwerner, J. P., Hucks, D., Dave, U., Zhao, Z., et al. (2015) · Blood

Cutaneous lymphoproliferative disorders researchLymphoma Diagnosis and Treatment

Cited by 232

Genome Stability Requires p53

Eischen, C. M. (2016) · Cold Spring Harbor Perspectives in Medicine

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 161

Mdm2 Binds to Nbs1 at Sites of DNA Damage and Regulates Double Strand Break Repair

Alt, J. R., Bouska, A., Fernandez, M. R., Cerny, R. L., Xiao, H., & Eischen, C. M. (2005) · Journal of Biological Chemistry

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 131

Mdm2 haplo‐insufficiency profoundly inhibits Myc‐induced lymphomagenesis

Alt, J. R., Greiner, T. C., Cleveland, J. L., & Eischen, C. M. (2003) · The EMBO Journal

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 129

Mdm2 Promotes Genetic Instability and Transformation Independent of p53

Bouska, A., Lushnikova, T., Plaza, S., & Eischen, C. M. (2008) · Molecular and Cellular Biology

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 105

Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells

Wang, P., Lushnikova, T., Odvody, J., Greiner, T. C., Jones, S. N., & Eischen, C. M. (2008) · Oncogene

Cancer-related Molecular PathwaysLymphoma Diagnosis and Treatment

Cited by 86

The Mdm network and its regulation of p53 activities: a rheostat of cancer risk

Eischen, C. M., & Lozano, G. (2014) · Human Mutation

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 79

Mdm2 affects genome stability independent of p53

Bouska, A., & Eischen, C. M. (2009) · Cancer Research

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 71

Mdmx promotes genomic instability independent of p53 and Mdm2

Carrillo, A. M., Bouska, A., Arrate, M. P., & Eischen, C. M. (2015) · Oncogene

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 69

Potentiation of carboplatin-mediated DNA damage by the Mdm2 modulator Nutlin-3a in a humanized orthotopic breast-to-lung metastatic model

Tonsing-Carter, E., Bailey, B. J., Saadatzadeh, M. R., Ding, J., Wang, H., Sinn, A. L., Peterman, K. M., Spragins, T. K., Silver, J. M., Sprouse, A. A., et al. (2015) · Molecular Cancer Therapeutics

Cancer-related Molecular PathwaysBreast Cancer Treatment Studies

Cited by 42

Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression

Lushnikova, T., Bouska, A., Odvody, J., Dupont, W. D., & Eischen, C. M. (2011) · Oncogene

Cancer-related Molecular PathwaysMicrotubule and mitosis dynamics

Cited by 40

Pharmacologically increasing Mdm2 Inhibits DNA repair and cooperates with genotoxic agents to kill p53-inactivated ovarian cancer cells

Carrillo, A. M., Hicks, M., Khabele, D., & Eischen, C. M. (2015) · Molecular Cancer Research

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 31

Protecting the genome from mdm2 and mdmx

Melo, A. N., & Eischen, C. M. (2012) · Genes & Cancer

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 20