Lam, Brian Y. H.

HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus

Steuernagel, L., Lam, B. Y. H., Klemm, P., Dowsett, G. K. C., Bauder, C. A., Tadross, J. A., Hitschfeld, T. S., del Rio Martin, A., Chen, W., de Solis, A. J., et al. (2022) · Nature Metabolism

Single-cell and spatial transcriptomicsPancreatic function and diabetes

Cited by 267

Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets

Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, J. J., Reimann, F., & Gribble, F. M. (2016) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 223

Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice

Rodriguez-Cuenca, S., Cochemé, H. M., Logan, A., Abakumova, I., Prime, T. A., Rose, C., Vidal-Puig, A., Smith, A. C., Rubinsztein, D. C., Fearnley, I. M., et al. (2010) · Free Radical Biology and Medicine

Mitochondrial Function and PathologyCoenzyme Q10 studies and effects

Cited by 218

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

Dalgaard, K., Landgraf, K., Heyne, S., Lempradl, A., Longinotto, J., Gossens, K., Ruf, M., Orthofer, M., Strogantsev, R., Selvaraj, M., et al. (2016) · Cell

Genetic Syndromes and ImprintingEpigenetics and DNA Methylation

Cited by 190

Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort

Wade, K. H., Lam, B. Y. H., Melvin, A., Pan, W., Corbin, L. J., Hughes, D. A., Rainbow, K., Chen, J.-H., Duckett, K., Liu, X., et al. (2021) · Nature Medicine

Regulation of Appetite and ObesityGenetic Associations and Epidemiology

Cited by 133

A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing

Dowsett, G. K. C., Lam, B. Y. H., Tadross, J. A., Cimino, I., Rimmington, D., Coll, A. P., Polex-Wolf, J., Knudsen, L. B., Pyke, C., & Yeo, G. S. H. (2021) · Molecular Metabolism

Regulation of Appetite and ObesitySingle-cell and spatial transcriptomics

Cited by 98

Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis

Vacca, M., Leslie, J., Virtue, S., Lam, B. Y. H., Govaere, O., Tiniakos, D., Snow, S., Davies, S., Petkevicius, K., Tong, Z., et al. (2020) · Nature Metabolism

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 60

Impaired Autophagy in CD11b + Dendritic Cells Expands CD4 + Regulatory T Cells and Limits Atherosclerosis in Mice

Clement, M., Raffort, J., Lareyre, F., Tsiantoulas, D., Newland, S., Lu, Y., Masters, L., Harrison, J., Saveljeva, S., Ma, M. K. L., et al. (2019) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesAutophagy in Disease and Therapy

Cited by 44

Obesity medication lorcaserin activates brainstem GLP-1 neurons to reduce food intake and augments GLP-1 receptor agonist induced appetite suppression

Wagner, S., Brierley, D. I., Leeson-Payne, A., Jiang, W., Chianese, R., Lam, B. Y. H., Dowsett, G. K. C., Cristiano, C., Lyons, D., Reimann, F., et al. (2023) · Molecular Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 32