Cowen, Philip J.

Subcortical brain alterations in major depressive disorder: Findings from the ENIGMA Major Depressive Disorder working group

for the ENIGMA-Major Depressive Disorder Working Group, Schmaal, L., Veltman, D. J., van Erp, T. G. M., Sämann, P. G., Frodl, T., Jahanshad, N., Loehrer, E., Tiemeier, H., Hofman, A., et al. (2016) · Molecular Psychiatry

Treatment of Major DepressionNeural and Behavioral Psychology Studies

Cited by 1,172

How do antidepressants work? New perspectives for refining future treatment approaches

Harmer, C. J., Duman, R. S., & Cowen, P. J. (2017) · The Lancet Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 616

Increased Positive Versus Negative Affective Perception and Memory in Healthy Volunteers Following Selective Serotonin and Norepinephrine Reuptake Inhibition

Harmer, C. J., Shelley, N. C., Cowen, P. J., & Goodwin, G. M. (2004) · American Journal of Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 554

Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action

Harmer, C. J., Goodwin, G. M., & Cowen, P. J. (2009) · British Journal of Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 542

Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers

Schmidt, K., Cowen, P. J., Harmer, C. J., Tzortzis, G., Errington, S., & Burnet, P. W. J. (2015) · Psychopharmacology

Microbial Metabolites in Food BiotechnologyProbiotics and Fermented Foods

Cited by 522

Effect of Acute Antidepressant Administration on Negative Affective Bias in Depressed Patients

Harmer, C. J., O’Sullivan, U., Favaron, E., Massey-Chase, R., Ayres, R., Reinecke, A., Goodwin, G. M., & Cowen, P. J. (2009) · American Journal of Psychiatry

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 485

Antidepressant Drug Treatment Modifies the Neural Processing of Nonconscious Threat Cues

Harmer, C. J., Mackay, C. E., Reid, C. B., Cowen, P. J., & Goodwin, G. M. (2006) · Biological Psychiatry

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

Cited by 450

Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers

Harmer, C. J., Bhagwagar, Z., Perrett, D. I., Völlm, B. A., Cowen, P. J., & Goodwin, G. M. (2003) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 420

Treatment-resistant depression and peripheral C-reactive protein.

Chamberlain, S. R., Cavanagh, J., de Boer, P., Mondelli, V., Jones, D. N. C., Drevets, W. C., Cowen, P. J., Harrison, N. A., Pointon, L., Pariante, C. M., et al. (2019) · British Journal of Psychiatry

Tryptophan and brain disordersTreatment of Major Depression

Cited by 400

Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment

McCabe, C., Mishor, Z., Cowen, P. J., & Harmer, C. J. (2010) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 365

Optimal dose of selective serotonin reuptake inhibitors, venlafaxine, and mirtazapine in major depression: a systematic review and dose-response meta-analysis

Furukawa, T. A., Cipriani, A., Cowen, P. J., Leucht, S., Egger, M., & Salanti, G. (2019) · The Lancet Psychiatry

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 322

Tryptophan depletion in normal volunteers produces selective impairments in learning and memory

Park, S. B., Coull, J. T., McShane, R. H., Young, A. H., Sahakian, B. J., Robbins, T. W., & Cowen, P. J. (1994) · Neuropharmacology

Neurotransmitter Receptor Influence on BehaviorTryptophan and brain disorders

Cited by 310

Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion

Morris, J. S., Smith, K. A., Cowen, P. J., Friston, K. J., & Dolan, R. J. (1999) · NeuroImage

Neurotransmitter Receptor Influence on BehaviorTryptophan and brain disorders

Cited by 288

Increased salivary cortisol after waking in depression

Bhagwagar, Z., Hafizi, S., & Cowen, P. J. (2005) · Psychopharmacology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 281

Toward a Neuropsychological Theory of Antidepressant Drug Action: Increase in Positive Emotional Bias After Potentiation of Norepinephrine Activity

Harmer, C. J., Hill, S. A., Taylor, M. J., Cowen, P. J., & Goodwin, G. M. (2003) · American Journal of Psychiatry

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 262

Effect of a single dose of citalopram on amygdala response to emotional faces

Murphy, S. E., Norbury, R., O'Sullivan, U., Cowen, P. J., & Harmer, C. J. (2009) · British Journal of Psychiatry

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 255

The effects of tryptophan depletion on cognitive and affective processing in healthy volunteers

Murphy, F., Smith, K., Cowen, P., Robbins, T., & Sahakian, B. (2002) · Psychopharmacology

Tryptophan and brain disordersNeurotransmitter Receptor Influence on Behavior

Cited by 255

Neural representation of reward in recovered depressed patients

McCabe, C., Cowen, P. J., & Harmer, C. J. (2009) · Psychopharmacology

Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

Cited by 248

A single dose of citalopram increases fear recognition in healthy subjects

Browning, M., Reid, C., Cowen, P. J., Goodwin, G. M., & Harmer, C. J. (2007) · Journal of Psychopharmacology

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeurotransmitter Receptor Influence on Behavior

Cited by 245

Short-term SSRI treatment normalises amygdala hyperactivity in depressed patients.

Godlewska, B. R., Norbury, R., Selvaraj, S., Cowen, P. J., & Harmer, C. J. (2012) · Psychological Medicine

Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 244

CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Mancuso, R., Fryatt, G., Cleal, M., Obst, J., Pipi, E., Monzón-Sandoval, J., Ribe, E., Winchester, L., Webber, C., Nevado, A., et al. (2019) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 235

A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials

Sforzini, L., Worrell, C., Kose, M., Anderson, I. M., Aouizerate, B., Arolt, V., Bauer, M., Baune, B. T., Blier, P., Cleare, A. J., et al. (2022) · Molecular Psychiatry

Treatment of Major DepressionDelphi Technique in Research

Cited by 214

Using Attentional Bias Modification as a Cognitive Vaccine Against Depression

Browning, M., Holmes, E. A., Charles, M., Cowen, P. J., & Harmer, C. J. (2012) · Biological Psychiatry

Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeural and Behavioral Psychology Studies

Cited by 197

Increased Waking Salivary Cortisol Levels in Young People at Familial Risk of Depression

Mannie, Z. N., Harmer, C. J., & Cowen, P. J. (2007) · American Journal of Psychiatry

Stress Responses and CortisolAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 192