Ge, Kai

Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation

Jin, Q., Yu, L., Wang, L., Zhang, Z., Kasper, L. H., Lee, J., Wang, C., Brindle, P. K., Dent, S. Y. R., & Ge, K. (2011) · The EMBO Journal

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 877

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

Lee, J.-E., Wang, C., Xu, S., Cho, Y.-W., Wang, L., Feng, X., Baldridge, A., Sartorelli, V., Zhuang, L., Peng, W., et al. (2013) · eLife

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 522

Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease

Zhu, M., Lu, T., Jia, Y., Luo, X., Gopal, P., Li, L., Odewole, M., Renteria, V., Singal, A. G., Jang, Y., et al. (2019) · Cell

Liver physiology and pathologyCancer Genomics and Diagnostics

Cited by 250

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition

Wang, C., Lee, J.-E., Lai, B., Macfarlan, T. S., Xu, S., Zhuang, L., Liu, C., Peng, W., & Ge, K. (2016) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 242

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis

Lai, B., Lee, J.-E., Jang, Y., Wang, L., Peng, W., & Ge, K. (2017) · Nucleic Acids Research

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 191

HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis

Sun, Y., Zhou, B., Mao, F., Xu, J., Miao, H., Zou, Z., Phuc Khoa, L. T., Jang, Y., Cai, S., Witkin, M., et al. (2018) · Cancer Cell

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 152

Targeted Disruption of the Murine Bin1/Amphiphysin II Gene Does Not Disable Endocytosis but Results in Embryonic Cardiomyopathy with Aberrant Myofibril Formation

Muller, A. J., Baker, J. F., DuHadaway, J. B., Ge, K., Farmer, G., Donover, P. S., Meade, R., Reid, C., Grzanna, R., Roach, A. H., et al. (2003) · Molecular and Cellular Biology

Congenital heart defects researchCardiomyopathy and Myosin Studies

Cited by 139

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program

Elliott, K., Ge, K., Du, W., & Prendergast, G. C. (2000) · Oncogene

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 106

MLL4 mediates differentiation and tumor suppression through ferroptosis

Egolf, S., Zou, J., Anderson, A., Simpson, C. L., Aubert, Y., Prouty, S., Ge, K., Seykora, J. T., & Capell, B. C. (2021) · Science Advances

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 88

KDM6A regulates cell plasticity and pancreatic cancer progression by noncanonical activin pathway

Yi, Z., Wei, S., Jin, L., Jeyarajan, S., Yang, J., Gu, Y., Kim, H. S., Schechter, S., Lu, S., Paulsen, M. T., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology

Pancreatic and Hepatic Oncology ResearchEpigenetics and DNA Methylation

Cited by 41

MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBP β and C/EBP δ

Lee, J.-E., Cho, Y.-W., Deng, C.-X., & Ge, K. (2020) · Molecular and Cellular Biology

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 26