Kestler, Hans A.

A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage

Wang, J., Sun, Q., Morita, Y., Jiang, H., Groß, A., Lechel, A., Hildner, K., Guachalla, L. M., Gompf, A., Hartmann, D., et al. (2012) · Cell

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

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A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

Florian, M. C., Nattamai, K. J., Dörr, K., Marka, G., Überle, B., Vas, V., Eckl, C., Andrä, I., Schiemann, M., Oostendorp, R. A. J., et al. (2013) · Nature

Hematopoietic Stem Cell TransplantationWnt/β-catenin signaling in development and cancer

Cited by 303

Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood

Song, Z., Von Figura, G., Liu, Y., Kraus, J. M., Torrice, C., Dillon, P., Rudolph‐Watabe, M., Ju, Z., Kestler, H. A., Sanoff, H., et al. (2010) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 163

Telomerase abrogates aneuploidy‐induced telomere replication stress, senescence and cell depletion

Meena, J. K., Cerutti, A., Beichler, C., Morita, Y., Bruhn, C., Kumar, M., Kraus, J. M., Speicher, M. R., Wang, Z., Kestler, H. A., et al. (2015) · The EMBO Journal

Telomeres, Telomerase, and SenescenceMicrotubule and mitosis dynamics

Cited by 87

Extended analyses of the Wnt/β-catenin pathway: Robustness and oscillatory behaviour

Wawra, C., Kühl, M., & Kestler, H. A. (2007) · FEBS Letters

Wnt/β-catenin signaling in development and cancerGene Regulatory Network Analysis

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Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo

Kustermann, M., Manta, L., Paone, C., Kustermann, J., Lausser, L., Wiesner, C., Eichinger, L., Clemen, C. S., Schröder, R., Kestler, H. A., et al. (2018) · Autophagy

Autophagy in Disease and TherapyMuscle Physiology and Disorders

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Naked mole-rat transcriptome signatures of socially suppressed sexual maturation and links of reproduction to aging

Bens, M., Szafranski, K., Holtze, S., Sahm, A., Groth, M., Kestler, H. A., Hildebrandt, T. B., & Platzer, M. (2018) · BMC Biology

Genetics, Aging, and Longevity in Model OrganismsAnimal Behavior and Reproduction

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Representing dynamic biological networks with multi-scale probabilistic models

Groß, A., Kracher, B., Kraus, J. M., Kühlwein, S. D., Pfister, A. S., Wiese, S., Luckert, K., Pötz, O., Joos, T., Van Daele, D., et al. (2019) · Communications Biology

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

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Leveraging quantum computing for dynamic analyses of logical networks in systems biology

Weidner, F. M., Schwab, J. D., Wölk, S., Rupprecht, F., Ikonomi, N., Werle, S. D., Hoffmann, S., Kühl, M., & Kestler, H. A. (2023) · Patterns

Quantum Computing Algorithms and ArchitectureGene Regulatory Network Analysis

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Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

Arnold, F., Mahaddalkar, P. U., Kraus, J. M., Zhong, X., Bergmann, W., Srinivasan, D., Gout, J., Roger, E., Beutel, A. K., Zizer, E., et al. (2021) · Advanced Science

Liver physiology and pathologyPluripotent Stem Cells Research

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A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage

Wang, J., Sun, Q., Morita, Y., Jiang, H., Groß, A., Lechel, A., Hildner, K., Guachalla, L. M., Gompf, A., Hartmann, D., et al. (2014) · Cell

Hematopoietic Stem Cell TransplantationDNA Repair Mechanisms

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Predicting disease progression in behavioral variant frontotemporal dementia

Anderl‐Straub, S., Lausser, L., Lombardi, J., Uttner, I., Fassbender, K., Fliessbach, K., Huppertz, H., Jahn, H., Kornhuber, J., Obrig, H., et al. (2021) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

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