Williams, Ann C.

The COX-2/PGE2 pathway, key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

Greenhough, A., Smartt, H. J. M., Moore, A. E., Roberts, H. R., Williams, A. C., Paraskeva, C., & Kaidi, A. (2009) · Carcinogenesis

Inflammatory mediators and NSAID effectsPeroxisome Proliferator-Activated Receptors

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Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia

Kaidi, A., Qualtrough, D., Williams, A. C., & Paraskeva, C. (2006) · Cancer Research

Inflammatory mediators and NSAID effectsCancer, Hypoxia, and Metabolism

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NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

Flanagan, D. J., Pentinmikko, N., Luopajärvi, K., Willis, N. J., Gilroy, K., Raven, A. P., Mcgarry, L., Englund, J. I., Webb, A. T., Scharaw, S., et al. (2021) · Nature

Wnt/β-catenin signaling in development and cancerGenetic factors in colorectal cancer

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Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway

Li, Y., Mao, Y., Brandt-Rauf, P. W., Williams, A. C., & Fine, R. L. (2005) · Molecular Cancer Therapeutics

Cancer-related Molecular PathwaysCell death mechanisms and regulation

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Optimized delivery of siRNA into 3D tumor spheroid cultures in situ

Morgan, R. G., Chambers, A. C., Legge, D. N., Coles, S. J., Greenhough, A., & Williams, A. C. (2018) · Scientific Reports

RNA Interference and Gene DeliveryMolecular Biology Techniques and Applications

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A rapid high throughput bioprinted colorectal cancer spheroid platform for in vitro drug- and radiation-response

Johnson, P. A., Menegatti, S., Chambers, A. C., Alibhai, D., Collard, T. J., Williams, A. C., Bayley, H., & Perriman, A. W. (2023) · Biofabrication

3D Printing in Biomedical ResearchHydrogels: synthesis, properties, applications

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