Ciccia, Alberto

The DNA Damage Response: Making It Safe to Play with Knives

Ciccia, A., & Elledge, S. J. (2010) · Molecular Cell

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 4,368

CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

Billon, P., Bryant, E. E., Joseph, S. A., Nambiar, T. S., Hayward, S. B., Rothstein, R., & Ciccia, A. (2017) · Molecular Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 363

Replication fork slowing and reversal upon DNA damage require PCNA polyubiquitination and ZRANB3 DNA translocase activity.

Vujanovic, M., Krietsch, J., Raso, M. C., Terraneo, N., Zellweger, R., Schmid, J. A., Taglialatela, A., Huang, J.-W., Holland, C. L., Zwicky, K., et al. (2017) · Molecular Cell

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 227

GET: a foundation model of transcription across human cell types

Fu, X., Mo, S., Buendia, A., Laurent, A., Shao, A., Alvares-Torres, M. D. M., Yu, T., Tan, J., Su, J., Sagatelian, R., et al. (2023) · Nature

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 130

A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability

O'Connell, B. C., Adamson, B., Lydeard, J. R., Sowa, M. E., Ciccia, A., Bredemeyer, A. L., Schlabach, M., Gygi, S. P., Elledge, S. J., & Harper, J. W. (2010) · Molecular Cell

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 122

Mechanism of DNA unwinding by hexameric MCM8-9 in complex with HROB

Acharya, A., Bret, H., Huang, J.-W., Muetze, M., Goese, M., Kissling, V., Seidel, R., Ciccia, A., Guérois, R., & Cejka, P. (2023) · Nature Communications

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 13

CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissue

Gu, J., Iyer, A., Wesley, B., Taglialatela, A., Leuzzi, G., Hangai, S., Decker, A., Gu, R., Klickstein, N., Shuai, Y., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

CRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics

Cited by 10