Willemsen, Rob

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

Simonis, M., Klous, P., Splinter, E., Moshkin, Y., Willemsen, R., de Wit, E., van Steensel, B., & de Laat, W. (2006) · Nature Genetics

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 1,386

Proteomic Analysis of Exosomes Isolated from Human Malignant Pleural Effusions

Bard, M. P., Hegmans, J. P., Hemmes, A., Luider, T. M., Willemsen, R., Severijnen, L.-A. A., van Meerbeeck, J. P., Burgers, S. A., Hoogsteden, H. C., & Lambrecht, B. N. (2004) · American Journal of Respiratory Cell and Molecular Biology

Extracellular vesicles in diseasePleural and Pulmonary Diseases

Cited by 416

Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

Verheij, C., Bakker, C. E., de Graaff, E., Keulemans, J., Willemsen, R., Verkerk, A. J. M. H., Galjaard, H., Reuser, A. J. J., Hoogeveen, A. T., & Oostra, B. A. (1993) · Nature

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 343

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

de Vrij, F. M. S., Levenga, J., van der Linde, H. C., Koekkoek, S. K., De Zeeuw, C. I., Nelson, D. L., Oostra, B. A., & Willemsen, R. (2008) · Neurobiology of Disease

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 313

In Vitro Reactivation of the FMR1 Gene Involved in Fragile X Syndrome

Chiurazzi, P., Pomponi, M. G., Willemsen, R., Oostra, B. A., & Neri, G. (1998) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation

Cited by 198

Characterization of the full fragile X syndrome mutation in fetal gametes

Malter, H. E., Iber, J. C., Willemsen, R., Graaff, E. D., Tarleton, J. C., Leisti, J., Warren, S. T., & Oostra, B. A. (1997) · Nature Genetics

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 197

Normal phenotype in two brothers with a full FMR1 mutation

Smeets, H. J. M., Smits, A. P. T., Verheij, C. E., Theelen, J. P. G., Willemsen, R., Burgt, I. V. D., Hoogeveen, A. T., Oosterwijk, J. C., & Oostra, B. A. (1995) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersGenetic Neurodegenerative Diseases

Cited by 179

Human lysosomal protective protein has cathepsin A-like activity distinct from its protective function

Galjart, N. J., Morreau, H., Willemsen, R., Gillemans, N., Bonten, E. J., & d'Azzo, A. (1991) · Journal of Biological Chemistry

Lysosomal Storage Disorders ResearchGlycogen Storage Diseases and Myoclonus

Cited by 158

Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex

Kwan, K. Y., Lam, M. M. S., Johnson, M. B., Dube, U., Shim, S., Rašin, M.-R., Sousa, A. M. M., Fertuzinhos, S., Chen, J.-G., Arellano, J. I., et al. (2012) · Cell

Genetics and Neurodevelopmental DisordersRNA Research and Splicing

Cited by 137

Exosomal Secretion of Cytoplasmic Prostate Cancer Xenograft-derived Proteins

Jansen, F. H., Krijgsveld, J., van Rijswijk, A., van den Bemd, G.-J., van den Berg, M. S., van Weerden, W. M., Willemsen, R., Dekker, L. J., Luider, T. M., & Jenster, G. (2009) · Molecular & Cellular Proteomics

Extracellular vesicles in diseaseAdvanced Proteomics Techniques and Applications

Cited by 107

Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice

Gantois, I., Pop, A. S., de Esch, C. E. F., Buijsen, R. A. M., Pooters, T., Gomez-Mancilla, B., Gasparini, F., Oostra, B. A., D’Hooge, R., & Willemsen, R. (2013) · Behavioural Brain Research

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 100

Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant

Pop, A. S., Levenga, J., de Esch, C. E. F., Buijsen, R. A. M., Nieuwenhuizen, I. M., Li, T., Isaacs, A., Gasparini, F., Oostra, B. A., & Willemsen, R. (2014) · Psychopharmacology

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 93

Lysosomal Protective Protein/Cathepsin A

Bonten, E. J., Galjart, N. J., Willemsen, R., Usmany, M., Vlak, J. M., & d'Azzo, A. (1995) · Journal of Biological Chemistry

Protease and Inhibitor MechanismsCellular transport and secretion

Cited by 59

Fragile X mice have robust mGluR5-dependent alterations of social behaviour in the Automated Tube Test

de Esch, C. E. F., van den Berg, W. E., Buijsen, R. A. M., Jaafar, I. A., Nieuwenhuizen-Bakker, I. M., Gasparini, F., Kushner, S. A., & Willemsen, R. (2015) · Neurobiology of Disease

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 45