Abel, E. Dale

Diabetic Cardiomyopathy Revisited

Boudina, S., & Abel, E. D. (2007) · Circulation

Cardiovascular Function and Risk FactorsCardiac Fibrosis and Remodeling

Cited by 1,543

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

Ho, P.-C., Bihuniak, J. D., Macintyre, A. N., Staron, M., Liu, X., Amezquita, R., Tsui, Y.-C., Cui, G., Micevic, G., Perales, J. C., et al. (2015) · Cell

Cancer, Hypoxia, and MetabolismCancer Immunotherapy and Biomarkers

Cited by 1,462

PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis

Leone, T. C., Lehman, J. J., Finck, B. N., Schaeffer, P. J., Wende, A. R., Boudina, S., Courtois, M., Wozniak, D. F., Sambandam, N., Bernal-Mizrachi, C., et al. (2005) · PLoS Biology

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 951

Molecular mechanisms of diabetic cardiomyopathy

Bugger, H., & Abel, E. D. (2014) · Diabetologia

Cardiovascular Function and Risk FactorsCardiac Fibrosis and Remodeling

Cited by 903

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance

Zisman, A., Peroni, O. D., Abel, E. D., Michael, M. D., Mauvais-Jarvis, F., Lowell, B. B., Wojtaszewski, J. F. P., Hirshman, M. F., Virkamaki, A., Goodyear, L. J., et al. (2000) · Nature Medicine

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 743

Cardiac remodeling in obesity

Abel, E. D., Litwin, S. E., & Sweeney, G. (2008) · Physiological Reviews

Cardiac Fibrosis and RemodelingCardiovascular Disease and Adiposity

Cited by 736

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

Trammell, S. A. J., Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., Li, Z., Abel, E. D., Migaud, M. E., & Brenner, C. (2016) · Nature Communications

Sirtuins and Resveratrol in MedicineFolate and B Vitamins Research

Cited by 697

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

Winkler, E. A., Nishida, Y., Sagare, A. P., Rege, S. V., Bell, R. D., Perlmutter, D., Sengillo, J. D., Hillman, S., Kong, P., Nelson, A. R., et al. (2015) · Nature Neuroscience

Barrier Structure and Function StudiesAlzheimer's disease research and treatments

Cited by 689

Mitochondrial Energetics in the Heart in Obesity-Related Diabetes

Boudina, S., Sena, S., Theobald, H., Sheng, X., Wright, J. J., Hu, X. X., Aziz, S., Johnson, J. I., Bugger, H., Zaha, V. G., et al. (2007) · Diabetes

Mitochondrial Function and PathologyCardiovascular Function and Risk Factors

Cited by 586

Reduced Cardiac Efficiency and Altered Substrate Metabolism Precedes the Onset of Hyperglycemia and Contractile Dysfunction in Two Mouse Models of Insulin Resistance and Obesity

Buchanan, J., Mazumder, P. K., Hu, P., Chakrabarti, G., Roberts, M. W., Yun, U. J., Cooksey, R. C., Litwin, S. E., & Abel, E. D. (2005) · Endocrinology

Cardiovascular Function and Risk FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 555

Reduced Mitochondrial Oxidative Capacity and Increased Mitochondrial Uncoupling Impair Myocardial Energetics in Obesity

Boudina, S., Sena, S., O’Neill, B. T., Tathireddy, P., Young, M. E., & Abel, E. D. (2005) · Circulation

Mitochondrial Function and PathologyCardiovascular Function and Risk Factors

Cited by 502

Impaired Cardiac Efficiency and Increased Fatty Acid Oxidation in Insulin-Resistant ob/ob Mouse Hearts

Mazumder, P. K., O’Neill, B. T., Roberts, M. W., Buchanan, J., Yun, U. J., Cooksey, R. C., Boudina, S., & Abel, E. D. (2004) · Diabetes

Cardiovascular Function and Risk FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 437

Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression

Bray, M. S., Shaw, C. A., Moore, M. W. S., Garcia, R. A. P., Zanquetta, M. M., Durgan, D. J., Jeong, W. J., Tsai, J.-Y., Bugger, H., Zhang, D., et al. (2008) · American Journal of Physiology-Heart and Circulatory Physiology

Circadian rhythm and melatoninCardiac electrophysiology and arrhythmias

Cited by 384

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

Belke, D. D., Betuing, S., Tuttle, M. J., Graveleau, C., Young, M. E., Pham, M., Zhang, D., Cooksey, R. C., McClain, D. A., Litwin, S. E., et al. (2002) · Journal of Clinical Investigation

Congenital heart defects researchCardiovascular Function and Risk Factors

Cited by 330

Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

Boudina, S., Bugger, H., Sena, S., O'Neill, B. T., Zaha, V. G., Ilkun, O., Wright, J. J., Mazumder, P. K., Palfreyman, E., Tidwell, T. J., et al. (2009) · Circulation

Mitochondrial Function and PathologyCardiovascular Function and Risk Factors

Cited by 301

Ablation of PGC-1β Results in Defective Mitochondrial Activity, Thermogenesis, Hepatic Function, and Cardiac Performance

Lelliott, C. J., Medina-Gomez, G., Petrovic, N., Kis, A., Feldmann, H. M., Bjursell, M., Parker, N., Curtis, K., Campbell, M., Hu, P., et al. (2006) · PLoS Biology

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 280

Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy

Abel, E. D., & Doenst, T. (2011) · Cardiovascular Research

Mitochondrial Function and PathologyCardiac Fibrosis and Remodeling

Cited by 263

The role of mPer2 clock gene in glucocorticoid and feeding rhythms

Yang, S., Liu, A., Weidenhammer, A., Cooksey, R. C., McClain, D., Kim, M. K., Aguilera, G., Abel, E. D., & Chung, J. H. (2009) · Endocrinology

Circadian rhythm and melatoninRegulation of Appetite and Obesity

Cited by 263

Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload

Hu, P., Zhang, D., Swenson, L., Chakrabarti, G., Abel, E. D., & Litwin, S. E. (2003) · American Journal of Physiology-Heart and Circulatory Physiology

Cardiac Fibrosis and RemodelingCardiovascular Function and Risk Factors

Cited by 245

OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance

Pereira, R. O., Tadinada, S. M., Zasadny, F. M., Oliveira, K. J., Pires, K. M. P., Olvera, A., Jeffers, J., Souvenir, R., Mcglauflin, R., Seei, A., et al. (2017) · The EMBO Journal

Fibroblast Growth Factor ResearchMitochondrial Function and Pathology

Cited by 211

Mitochondrial Uncoupling: A Key Contributor to Reduced Cardiac Efficiency in Diabetes

Boudina, S., & Abel, E. D. (2006) · Physiology

Mitochondrial Function and PathologyCardiovascular Function and Risk Factors

Cited by 199

Critical role for thyroid hormone receptor β2 in the regulation of paraventricular thyrotropin-releasing hormone neurons

Abel, E. D., Ahima, R. S., Boers, M.-E., Elmquist, J. K., & Wondisford, F. E. (2001) · Journal of Clinical Investigation

Thyroid Disorders and TreatmentsHypothalamic control of reproductive hormones

Cited by 192

NADPH Oxidase-derived Reactive Oxygen Species Increases Expression of Monocyte Chemotactic Factor Genes in Cultured Adipocytes

Han, C. Y., Umemoto, T., Omer, M., Den Hartigh, L. J., Chiba, T., LeBoeuf, R., Buller, C. L., Sweet, I. R., Pennathur, S., Abel, E. D., et al. (2012) · Journal of Biological Chemistry

Adipokines, Inflammation, and Metabolic DiseasesRedox biology and oxidative stress

Cited by 187

Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3

Bugger, H., Boudina, S., Hu, X. X., Tuinei, J., Zaha, V. G., Theobald, H. A., Yun, U. J., McQueen, A. P., Wayment, B., Litwin, S. E., et al. (2008) · Diabetes

Mitochondrial Function and PathologyCardiovascular Function and Risk Factors

Cited by 182