Casellas, Rafael

Cohesin Loss Eliminates All Loop Domains

Rao, S. S. P., Huang, S.-C., Glenn St Hilaire, B., Engreitz, J. M., Perez, E. M., Kieffer-Kwon, K.-R., Sanborn, A. L., Johnstone, S. E., Bascom, G. D., Bochkov, I. D., et al. (2017) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

Wang, Z., Schmidt, F., Weisblum, Y., Muecksch, F., Barnes, C. O., Finkin, S., Schaefer-Babajew, D., Cipolla, M., Gaebler, C., Lieberman, J. A., et al. (2021) · Nature

SARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approaches

Cited by 1,343

The Energetics and Physiological Impact of Cohesin Extrusion

Vian, L., Pękowska, A., Rao, S. S. P., Kieffer-Kwon, K.-R., Jung, S., Baranello, L., Huang, S.-C., El Khattabi, L., Dose, M., Pruett, N., et al. (2018) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 581

Genome Organization Drives Chromosome Fragility

Canela, A., Maman, Y., Jung, S., Wong, N., Callen, E., Day, A., Kieffer-Kwon, K.-R., Pekowska, A., Zhang, H., Rao, S. S. P., et al. (2017) · Cell

Genomics and Chromatin DynamicsDNA Repair Mechanisms

Cited by 383

The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

Kruhlak, M., Crouch, E. E., Orlov, M., Montaño, C., Gorski, S. A., Nussenzweig, A., Misteli, T., Phair, R. D., & Casellas, R. (2007) · Nature

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 305

A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers

El Khattabi, L., Zhao, H., Kalchschmidt, J., Young, N., Jung, S., Van Blerkom, P., Kieffer-Kwon, P., Kieffer-Kwon, K.-R., Park, S., Wang, X., et al. (2019) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 244

Neuronal enhancers are hotspots for DNA single-strand break repair

Wu, W., Kargbo-Hill, S. E., Nathan, W. J., Paiano, J., Callen, E., Wang, D., Shinoda, K., van Wietmarschen, N., Colón-Mercado, J. M., Zong, D., et al. (2021) · Nature

DNA Repair MechanismsPARP inhibition in cancer therapy

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Global Regulation of Promoter Melting in Naive Lymphocytes

Kouzine, F., Wojtowicz, D., Yamane, A., Resch, W., Kieffer-Kwon, K.-R., Bandle, R., Nelson, S., Nakahashi, H., Awasthi, P., Feigenbaum, L., et al. (2013) · Cell

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 154

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3

Steward-Tharp, S. M., Laurence, A., Kanno, Y., Kotlyar, A., Villarino, A. V., Sciume, G., Kuchen, S., Resch, W., Wohlfert, E. A., Jiang, K., et al. (2014) · Blood

Immunodeficiency and Autoimmune DisordersCytokine Signaling Pathways and Interactions

Cited by 87

Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency

Pękowska, A., Klaus, B., Xiang, W., Severino, J., Daigle, N., Klein, F. A., Oleś, M., Casellas, R., Ellenberg, J., Steinmetz, L. M., et al. (2018) · Cell Systems

Genomics and Chromatin DynamicsPluripotent Stem Cells Research

Cited by 74

Immunogenomic determinants of exceptional response to immune checkpoint inhibition in renal cell carcinoma

Jammihal, T., Saliby, R. M., Labaki, C., Soulati, H., Gallegos, J., Peris, A., McCurry, D., Yu, C., Shah, V., Poduval, D., et al. (2025) · Nature Cancer

Cancer Immunotherapy and BiomarkersRenal cell carcinoma treatment

Cited by 38