Morschhäuser, Joachim

The Transcription Factor Mrr1p Controls Expression of the MDR1 Efflux Pump and Mediates Multidrug Resistance in Candida albicans

Morschhäuser, J., Barker, K. S., Liu, T. T., Blaß-Warmuth, J., Homayouni, R., & Rogers, P. D. (2007) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 355

A Human-Curated Annotation of the Candida albicans Genome

Braun, B. R., van het Hoog, M., d'Enfert, C., Martchenko, M., Dungan, J., Kuo, A., Inglis, D. O., Uhl, M. A., Hogues, H., Berriman, M., et al. (2005) · PLoS Genetics

Fungal and yeast genetics researchGenomics and Phylogenetic Studies

Cited by 342

Regulation of multidrug resistance in pathogenic fungi

Morschhäuser, J. (2010) · Fungal Genetics and Biology

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 300

Mutations in the multi‐drug resistance regulator MRR1 , followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole‐resistant Candida albicans strains

Dunkel, N., Blaß, J., Rogers, P. D., & Morschhäuser, J. (2008) · Molecular Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 278

Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans

Flowers, S. A., Barker, K. S., Berkow, E. L., Toner, G., Chadwick, S. G., Gygax, S. E., Morschhäuser, J., & Rogers, P. D. (2012) · Eukaryotic Cell

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 239

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers

Allert, S., Förster, T. M., Svensson, C.-M., Richardson, J. P., Pawlik, T., Hebecker, B., Rudolphi, S., Juraschitz, M., Schaller, M., Blagojevic, M., et al. (2018) · mBio

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 208

Regulation of Efflux Pump Expression and Drug Resistance by the Transcription Factors Mrr1, Upc2, and Cap1 in Candida albicans

Schubert, S., Barker, K. S., Znaidi, S., Schneider, S., Dierolf, F., Dunkel, N., Aïd, M., Boucher, G., Rogers, P. D., Raymond, M., et al. (2011) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 135

Molecular aspects of fluconazole resistance development in Candida albicans

Franz, R., Ruhnke, M., & Morschhäuser, J. (1999) · Mycoses

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 129

The development of fluconazole resistance in Candida albicans – an example of microevolution of a fungal pathogen

Morschhäuser, J. (2016) · Journal of Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 118

The stepwise acquisition of fluconazole resistance mutations causes a gradual loss of fitness in Candida albicans

Sasse, C., Dunkel, N., Schäfer, T., Schneider, S., Dierolf, F., Ohlsen, K., & Morschhäuser, J. (2012) · Molecular Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 93

Analysis of a fungus‐specific transcription factor family, the Candida albicans zinc cluster proteins, by artificial activation

Schillig, R., & Morschhäuser, J. (2013) · Molecular Microbiology

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 85

The Transcription Factor Ndt80 Does Not Contribute to Mrr1-, Tac1-, and Upc2-Mediated Fluconazole Resistance in Candida albicans

Sasse, C., Schillig, R., Dierolf, F., Weyler, M., Schneider, S., Mogavero, S., Rogers, P. D., & Morschhäuser, J. (2011) · PLoS ONE

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 61

Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains

Popp, C., Hampe, I. A. I., Hertlein, T., Ohlsen, K., Rogers, P. D., & Morschhäuser, J. (2017) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 56

In Vitro Activities of the Novel Investigational Tetrazoles VT-1161 and VT-1598 Compared to the Triazole Antifungals against Azole-Resistant Strains and Clinical Isolates of Candida albicans

Nishimoto, A. T., Wiederhold, N. P., Flowers, S. A., Zhang, Q., Kelly, S. L., Morschhäuser, J., Yates, C. M., Hoekstra, W. J., Schotzinger, R. J., Garvey, E. P., et al. (2019) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 52

Differential Requirement of the Transcription Factor Mcm1 for Activation of the Candida albicans Multidrug Efflux Pump MDR1 by Its Regulators Mrr1 and Cap1

Mogavero, S., Tavanti, A., Senesi, S., Rogers, P. D., & Morschhäuser, J. (2011) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 49

Functional Dissection of a Candida albicans Zinc Cluster Transcription Factor, the Multidrug Resistance Regulator Mrr1

Schubert, S., Popp, C., Rogers, P. D., & Morschhäuser, J. (2011) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 39

SAGA/ADA Complex Subunit Ada2 Is Required for Cap1- but Not Mrr1-Mediated Upregulation of the Candida albicans Multidrug Efflux Pump MDR1

Ramírez-Zavala, B., Mogavero, S., Schöller, E., Sasse, C., Rogers, P. D., & Morschhäuser, J. (2014) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 25

Loss of Heterozygosity at an Unlinked Genomic Locus Is Responsible for the Phenotype of a Candida albicans sap4 Δ sap5 Δ sap6 Δ Mutant

Dunkel, N., & Morschhäuser, J. (2011) · Eukaryotic Cell

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 20