Sontheimer, Erik J.

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

Hou, Z., Zhang, Y., Propson, N. E., Howden, S. E., Chu, L.-F., Sontheimer, E. J., & Thomson, J. A. (2013) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringPluripotent Stem Cells Research

Cited by 681

Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses

Wang, D., Mou, H., Li, S., Li, Y., Hough, S., Tran, K., Li, J., Yin, H., Anderson, D. G., Sontheimer, E. J., et al. (2015) · Human Gene Therapy

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 345

Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice

Liu, P., Liang, S.-Q., Zheng, C., Mintzer, E., Zhao, Y. G., Ponnienselvan, K., Mir, A., Sontheimer, E. J., Gao, G., Flotte, T. R., et al. (2021) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 273

A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing

Edraki, A., Mir, A., Ibraheim, R., Gainetdinov, I., Yoon, Y., Song, C.-Q., Cao, Y., Gallant, J., Xue, W., Rivera-Pérez, J. A., et al. (2019) · Molecular Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 265

Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins

Lee, J., Mou, H., Ibraheim, R., Liang, S.-Q., Liu, P., Xue, W., & Sontheimer, E. J. (2019) · RNA

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 100

PAM-flexible genome editing with an engineered chimeric Cas9

Zhao, L., Koseki, S. R. T., Silverstein, R. A., Amrani, N., Peng, C., Kramme, C., Savic, N., Pacesa, M., Rodríguez, T. C., Stan, T., et al. (2023) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 59

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

Liang, S.-Q., Liu, P., Smith, J. L., Mintzer, E., Maitland, S., Dong, X., Yang, Q., Lee, J., Haynes, C. M., Zhu, L. J., et al. (2022) · Nature Communications

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 54