Fan, Yiping

Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity

Prinzing, B., Zebley, C. C., Petersen, C. T., Fan, Y., Anido, A. A., Yi, Z., Nguyen, P., Houke, H., Bell, M., Haydar, D., et al. (2021) · Science Translational Medicine

CAR-T cell therapy researchT-cell and B-cell Immunology

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Developmental plasticity allows outside-in immune responses by resident memory T cells

Fonseca, R., Beura, L. K., Quarnstrom, C. F., Ghoneim, H. E., Fan, Y., Zebley, C. C., Scott, M. C., Fares-Frederickson, N. J., Wijeyesinghe, S., Thompson, E. A., et al. (2020) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity

Karmaus, P. W. F., Chen, X., Lim, S. A., Herrada, A. A., Nguyen, T.-L. M., Xu, B., Dhungana, Y., Rankin, S., Chen, W., Rosencrance, C., et al. (2019) · Nature

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

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The genomic basis of childhood T-lineage acute lymphoblastic leukemia

Mullighan, C., Pölönen, P., Giacomo, D. D., Seffernick, A., Elsayed, A., Kimura, S., Benini, F., Montefiori, L., Wood, B., Xu, J., et al. (2023) · Nature

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

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The genomic basis of childhood T-lineage acute lymphoblastic leukaemia

Pölönen, P., Di Giacomo, D., Seffernick, A. E., Elsayed, A., Kimura, S., Benini, F., Montefiori, L. E., Wood, B. L., Xu, J., Chen, C., et al. (2024) · Nature

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

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NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

Paugh, S. W., Bonten, E. J., Savic, D., Ramsey, L. B., Thierfelder, W. E., Gurung, P., Malireddi, R. K. S., Actis, M., Mayasundari, A., Min, J., et al. (2015) · Nature Genetics

Acute Lymphoblastic Leukemia researchInflammasome and immune disorders

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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

Stewart, E., McEvoy, J., Wang, H., Chen, X., Honnell, V., Ocarz, M., Gordon, B., Dapper, J., Blankenship, K., Yang, Y., et al. (2018) · Cancer Cell

Sarcoma Diagnosis and TreatmentChromatin Remodeling and Cancer

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Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells

Diouf, B., Cheng, Q., Krynetskaia, N. F., Yang, W., Cheok, M., Pei, D., Fan, Y., Cheng, C., Krynetskiy, E. Y., Geng, H., et al. (2011) · Nature Medicine

DNA Repair MechanismsAcute Lymphoblastic Leukemia research

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Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes

Abdelsamed, H. A., Zebley, C. C., Nguyen, H., Rutishauser, R. L., Fan, Y., Ghoneim, H. E., Crawford, J. C., Alfei, F., Alli, S., Ribeiro, S. P., et al. (2020) · Nature Immunology

Diabetes and associated disordersT-cell and B-cell Immunology

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Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs

Dobson, S. M., García-Prat, L., Vanner, R. J., Wintersinger, J., Waanders, E., Gu, Z., McLeod, J., Gan, O. I., Grandal, I., Payne-Turner, D., et al. (2020) · Cancer Discovery

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

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A Key Role for the Ubiquitin Ligase UBR4 in Myofiber Hypertrophy in Drosophila and Mice

Hunt, L. C., Stover, J., Haugen, B., Shaw, T. I., Li, Y., Pagala, V. R., Finkelstein, D., Barton, E. R., Fan, Y., Labelle, M., et al. (2019) · Cell Reports

Muscle Physiology and DisordersUbiquitin and proteasome pathways

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The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling

Hunt, L. C., Xu, B., Finkelstein, D., Fan, Y., Carroll, P. A., Cheng, P.-F., Eisenman, R. N., & Demontis, F. (2015) · Genes & Development

Muscle Physiology and DisordersMetabolism, Diabetes, and Cancer

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ChIPseqSpikeInFree: a ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in

Jin, H., Kasper, L. H., Larson, J. D., Wu, G., Baker, S. J., Zhang, J., & Fan, Y. (2020) · Bioinformatics

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

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Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Zhao, Y., Short, N. J., Kantarjian, H. M., Chang, T.-C., Ghate, P. S., Qu, C., Macaron, W., Jain, N., Thakral, B., Phillips, A. H., et al. (2023) · Blood

Acute Lymphoblastic Leukemia researchCAR-T cell therapy research

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Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Zhao, Y., Short, N. J., Kantarjian, H. M., Chang, T.-C., Ghate, P. S., Qu, C., Macaron, W., Jain, N., Thakral, B., Phillips, A. H., et al. (2024) · Blood

Acute Lymphoblastic Leukemia researchCAR-T cell therapy research

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