Flannery, John G.

In Vivo–Directed Evolution of a New Adeno-Associated Virus for Therapeutic Outer Retinal Gene Delivery from the Vitreous

Dalkara, D., Byrne, L. C., Klimczak, R. R., Visel, M., Yin, L., Merigan, W. H., Flannery, J. G., & Schaffer, D. V. (2013) · Science Translational Medicine

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 734

Activation of specific interneurons improves V1 feature selectivity and visual perception

Lee, S.-H., Kwan, A. C., Zhang, S., Phoumthipphavong, V., Flannery, J. G., Masmanidis, S. C., Taniguchi, H., Huang, Z. J., Zhang, F., Boyden, E. S., et al. (2012) · Nature

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 593

Inner limiting membrane barriers to aav-mediated retinal transduction from the vitreous

Dalkara, D., Kolstad, K. D., Caporale, N., Visel, M., Klimczak, R. R., Schaffer, D. V., & Flannery, J. G. (2009) · Molecular Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 357

Intravitreal injection of AAV2 transduces macaque inner retina

Yin, L., Greenberg, K., Hunter, J. J., Dalkara, D., Kolstad, K. D., Masella, B. D., Wolfe, R., Visel, M., Stone, D., Libby, R. T., et al. (2011) · Investigative Opthalmology & Visual Science

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 212

A Novel Adeno-Associated Viral Variant for Efficient and Selective Intravitreal Transduction of Rat Müller Cells

Klimczak, R. R., Koerber, J. T., Dalkara, D., Flannery, J. G., & Schaffer, D. V. (2009) · PLoS ONE

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 210

Ribozyme rescue of photoreceptor cells in P23H transgenic rats: Long-term survival and late-stage therapy

LaVail, M. M., Yasumura, D., Matthes, M. T., Drenser, K. A., Flannery, J. G., Lewin, A. S., & Hauswirth, W. W. (2000) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRNA Interference and Gene Delivery

Cited by 203

LiGluR restores visual responses in rodent models of inherited blindness

Caporale, N., Kolstad, K. D., Lee, T., Tochitsky, I., Dalkara, D., Trauner, D., Kramer, R., Dan, Y., Isacoff, E. Y., & Flannery, J. G. (2011) · Molecular Therapy

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 182

Molecular evolution of adeno-associated virus for enhanced glial gene delivery

Koerber, J. T., Klimczak, R., Jang, J.-H., Dalkara, D., Flannery, J. G., & Schaffer, D. V. (2009) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 181

Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates

Kotterman, M. A., Yin, L., Strazzeri, J. M., Flannery, J. G., Merigan, W. H., & Schaffer, D. V. (2015) · Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 169

In vivo–directed evolution of adeno-associated virus in the primate retina

Byrne, L. C., Day, T. P., Visel, M., Strazzeri, J. A., Fortuny, C., Dalkara, D., Merigan, W. H., Schaffer, D. V., & Flannery, J. G. (2020) · JCI Insight

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 104

Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h−/− mouse

Byrne, L. C., Öztürk, B. E., Lee, T., Fortuny, C., Visel, M., Dalkara, D., Schaffer, D. V., & Flannery, J. G. (2014) · Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 96

Recombinant AAV-mediated delivery of a tet-inducible reporter gene to the rat retina

McGee Sanftner, L. H., Rendahl, K. G., Quiroz, D., Coyne, M., Ladner, M., Manning, W. C., & Flannery, J. G. (2001) · Molecular Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 94

Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models

Pellissier, L. P., Quinn, P. M., Alves, C. H., Vos, R. M., Klooster, J., Flannery, J. G., Heimel, J. A., & Wijnholds, J. (2015) · Human Molecular Genetics

Retinal Development and DisordersVirus-based gene therapy research

Cited by 86

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

Hickey, D. G., Edwards, T. L., Barnard, A. R., Singh, M. S., de Silva, S. R., McClements, M. E., Flannery, J. G., Hankins, M. W., & MacLaren, R. E. (2017) · Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 72

Gene therapy for inherited retinal disease: Long-term durability of effect

Leroy, B. P., Fischer, M. D., Flannery, J. G., MacLaren, R. E., Dalkara, D., Scholl, H. P. N., Chung, D. C., Spera, C., Viriato, D., & Banhazi, J. (2023) · Ophthalmic Research

Retinal Development and DisordersVirus-based gene therapy research

Cited by 70

Changes in adeno-associated virus-mediated gene delivery in retinal degeneration

Kolstad, K. D., Dalkara, D., Guerin, K., Visel, M., Hoffmann, N., Schaffer, D. V., & Flannery, J. G. (2010) · Human Gene Therapy

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 63

Specific tools for targeting and expression in Müller glial cells

Pellissier, L. P., Hoek, R. M., Vos, R. M., Aartsen, W. M., Klimczak, R. R., Hoyng, S. A., Flannery, J. G., & Wijnholds, J. (2014) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 58

Imaging light responses of foveal ganglion cells in the living macaque eye

Yin, L., Masella, B., Dalkara, D., Zhang, J., Flannery, J. G., Schaffer, D. V., Williams, D. R., & Merigan, W. H. (2014) · The Journal of Neuroscience

Retinal Development and DisordersVisual perception and processing mechanisms

Cited by 54

AAV‐mediated gene delivery in Dp71‐null mouse model with compromised barriers

Vacca, O., Darche, M., Schaffer, D. V., Flannery, J. G., Sahel, J., Rendon, A., & Dalkara, D. (2014) · Glia

Retinal Development and DisordersVirus-based gene therapy research

Cited by 48