Zou, Lee

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Sharma, S. V., Lee, D. Y., Li, B., Quinlan, M. P., Takahashi, F., Maheswaran, S., McDermott, U., Azizian, N., Zou, L., Fischbach, M. A., et al. (2010) · Cell

Cancer Cells and MetastasisEpigenetics and DNA Methylation

Cited by 2,770

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Zou, L., & Elledge, S. J. (2003) · Science

DNA Repair MechanismsFungal and yeast genetics research

Cited by 2,693

DNA Damage Sensing by the ATM and ATR Kinases

Marechal, A., & Zou, L. (2013) · Cold Spring Harbor Perspectives in Biology

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 1,514

RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response

Maréchal, A., & Zou, L. (2015) · Cell Research

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 465

Replication protein A-mediated recruitment and activation of Rad17 complexes

Zou, L., Liu, D., & Elledge, S. J. (2003) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 431

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

Shiotani, B., & Zou, L. (2009) · Molecular Cell

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 353

Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase

Buisson, R., Boisvert, J. L., Benes, C. H., & Zou, L. (2015) · Molecular Cell

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 316

ATR: a master conductor of cellular responses to DNA replication stress

Flynn, R. L., & Zou, L. (2011) · Trends in Biochemical Sciences

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 290

ATR autophosphorylation as a molecular switch for checkpoint activation

Liu, S., Shiotani, B., Lahiri, M., Maréchal, A., Tse, A., Leung, C. C. Y., Glover, J. N. M., Yang, X. H., & Zou, L. (2011) · Molecular Cell

DNA Repair MechanismsProtein Kinase Regulation and GTPase Signaling

Cited by 281

Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition

Comaills, V., Kabeche, L., Morris, R., Buisson, R., Yu, M., Madden, M. W., LiCausi, J. A., Boukhali, M., Tajima, K., Pan, S., et al. (2016) · Cell Reports

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 124

Chk1 and Claspin potentiate PCNA ubiquitination

Yang, X. H., Shiotani, B., Classon, M., & Zou, L. (2008) · Genes & Development

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 111

Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium

Gross, K. M., Zhou, W., Breindel, J. L., Ouyang, J., Jin, D. X., Sokol, E. S., Gupta, P. B., Huber, K., Zou, L., & Kuperwasser, C. (2019) · Cell Reports

DNA Repair MechanismsTelomeres, Telomerase, and Senescence

Cited by 58

The BRCA1-Interacting Protein Abraxas Is Required for Genomic Stability and Tumor Suppression

Castillo, A., Paul, A., Sun, B., Huang, T. H., Wang, Y., Yazinski, S. A., Tyler, J., Li, L., You, M. J., Zou, L., et al. (2014) · Cell Reports

BRCA gene mutations in cancerDNA Repair Mechanisms

Cited by 39