Powell, Jonathan D.

Role of LAG-3 in Regulatory T Cells

Huang, C.-T., Workman, C. J., Flies, D., Pan, X., Marson, A. L., Zhou, G., Hipkiss, E. L., Ravi, S., Kowalski, J., Levitsky, H. I., et al. (2004) · Immunity

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 1,325

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

Leone, R. D., Zhao, L., Englert, J. M., Sun, I.-M., Oh, M.-H., Sun, I.-H., Arwood, M. L., Bettencourt, I. A., Patel, C. H., Wen, J., et al. (2019) · Science

Cancer, Hypoxia, and MetabolismCancer Immunotherapy and Biomarkers

Cited by 1,169

Metabolism of immune cells in cancer

Leone, R. D., & Powell, J. D. (2020) · Nature Reviews Cancer

Cancer, Hypoxia, and MetabolismCancer Immunotherapy and Biomarkers

Cited by 877

Regulation of Immune Responses by mTOR

Powell, J. D., Pollizzi, K. N., Heikamp, E. B., & Horton, M. R. (2012) · Annual Review of Immunology

PI3K/AKT/mTOR signaling in cancerT-cell and B-cell Immunology

Cited by 836

Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2

Scheibner, K. A., Lutz, M. A., Boodoo, S., Fenton, M. J., Powell, J. D., & Horton, M. R. (2006) · The Journal of Immunology

Proteoglycans and glycosaminoglycans researchImmune Response and Inflammation

Cited by 708

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

Sadtler, K., Estrellas, K., Allen, B. W., Wolf, M. T., Fan, H., Tam, A. J., Patel, C. H., Luber, B. S., Wang, H., Wagner, K. R., et al. (2016) · Science

Wound Healing and TreatmentsTissue Engineering and Regenerative Medicine

Cited by 605

Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells

Oh, M.-H., Sun, I.-H., Zhao, L., Leone, R. D., Sun, I.-M., Xu, W., Collins, S. L., Tam, A. J., Blosser, R. L., Patel, C. H., et al. (2020) · Journal of Clinical Investigation

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 456

mTOR , metabolism, and the regulation of T‐cell differentiation and function

Waickman, A. T., & Powell, J. D. (2012) · Immunological Reviews

PI3K/AKT/mTOR signaling in cancerT-cell and B-cell Immunology

Cited by 420

A role for mammalian target of rapamycin in regulating T cell activation versus anergy

Zheng, Y., Collins, S. L., Lutz, M. A., Allen, A. N., Kole, T. P., Zarek, P. E., & Powell, J. D. (2007) · The Journal of Immunology

T-cell and B-cell ImmunologyPI3K/AKT/mTOR signaling in cancer

Cited by 274

Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation

Michalek, R. D., Gerriets, V. A., Nichols, A. G., Inoue, M., Kazmin, D., Chang, C.-Y., Dwyer, M. A., Nelson, E. R., Pollizzi, K. N., Ilkayeva, O., et al. (2011) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 216

De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8 + T-cell fate decisions following activation

Ladle, B. H., Li, K.-P., Phillips, M. J., Pucsek, A. B., Haile, A., Powell, J. D., Jaffee, E. M., Hildeman, D. A., & Gamper, C. J. (2016) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyEpigenetics and DNA Methylation

Cited by 152

Discovery of 6-Diazo-5-oxo- l -norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma

Rais, R., Jančařík, A., Tenora, L., Nedelcovych, M., Alt, J., Englert, J., Rojas, C., Le, A., Elgogary, A., Tan, J., et al. (2016) · Journal of Medicinal Chemistry

Glioma Diagnosis and TreatmentAmino Acid Enzymes and Metabolism

Cited by 138

PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress

Ranek, M. J., Kokkonen-Simon, K. M., Chen, A., Dunkerly-Eyring, B. L., Vera, M. P., Oeing, C. U., Patel, C. H., Nakamura, T., Zhu, G., Bedja, D., et al. (2019) · Nature

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 130

Something in the Air: Hyperoxic Conditioning of the Tumor Microenvironment for Enhanced Immunotherapy

Leone, R. D., Horton, M. R., & Powell, J. D. (2015) · Cancer Cell

Cancer Immunotherapy and BiomarkersCancer, Hypoxia, and Metabolism

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