Treutlein, Barbara

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

Treutlein, B., Brownfield, D. G., Wu, A. R., Neff, N. F., Mantalas, G. L., Espinoza, F. H., Desai, T. J., Krasnow, M. A., & Quake, S. R. (2014) · Nature

Single-cell and spatial transcriptomicsNeonatal Respiratory Health Research

Cited by 1,342

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

Camp, J. G., Badsha, F., Florio, M., Kanton, S., Gerber, T., Wilsch-Bräuninger, M., Lewitus, E., Sykes, A., Hevers, W., Lancaster, M., et al. (2015) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsSingle-cell and spatial transcriptomics

Cited by 1,130

Quantitative assessment of single-cell RNA-sequencing methods

Wu, A. R., Neff, N. F., Kalisky, T., Dalerba, P., Treutlein, B., Rothenberg, M. E., Mburu, F. M., Mantalas, G. L., Sim, S., Clarke, M. F., et al. (2014) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 696

Multilineage communication regulates human liver bud development from pluripotency

Camp, J. G., Sekine, K., Gerber, T., Loeffler-Wirth, H., Binder, H., Gac, M., Kanton, S., Kageyama, J., Damm, G., Seehofer, D., et al. (2017) · Nature

Pluripotent Stem Cells ResearchLiver physiology and pathology

Cited by 621

Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq

Gokce, O., Stanley, G. M., Treutlein, B., Neff, N. F., Camp, J. G., Malenka, R. C., Rothwell, P. E., Fuccillo, M. V., Südhof, T. C., & Quake, S. R. (2016) · Cell Reports

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 430

Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration

Gerber, T., Murawala, P., Knapp, D., Masselink, W., Schuez, M., Hermann, S., Gac-Santel, M., Nowoshilow, S., Kageyama, J., Khattak, S., et al. (2018) · Science

Planarian Biology and ElectrostimulationDevelopmental Biology and Gene Regulation

Cited by 415

Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing

Treutlein, B., Gokce, O., Quake, S. R., & Südhof, T. C. (2014) · Proceedings of the National Academy of Sciences

RNA Research and SplicingNeuroscience and Neuropharmacology Research

Cited by 348

Inferring and perturbing cell fate regulomes in human brain organoids

Fleck, J. S., Jansen, S. M. J., Wollny, D., Zenk, F., Seimiya, M., Jain, A., Okamoto, R., Santel, M., He, Z., Camp, J. G., et al. (2023) · Nature

Neurogenesis and neuroplasticity mechanismsSingle-cell and spatial transcriptomics

Cited by 315

Single-cell brain organoid screening identifies developmental defects in autism

Li, C., Fleck, J. S., Martins-Costa, C., Burkard, T. R., Themann, J., Stuempflen, M., Peer, A. M., Vertesy, Á., Littleboy, J. B., Esk, C., et al. (2023) · Nature

Pluripotent Stem Cells ResearchGenetics and Neurodevelopmental Disorders

Cited by 283

Fluorescent biological aerosol particle concentrations and size distributions measured with an Ultraviolet Aerodynamic Particle Sizer (UV-APS) in Central Europe

Huffman, J. A., Treutlein, B., & Pöschl, U. (2010) · Atmospheric Chemistry and Physics

Atmospheric chemistry and aerosolsIndoor Air Quality and Microbial Exposure

Cited by 212

Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

Churko, J. M., Garg, P., Treutlein, B., Venkatasubramanian, M., Wu, H., Lee, J., Wessells, Q. N., Chen, S.-Y., Chen, W.-Y., Chetal, K., et al. (2018) · Nature Communications

Pluripotent Stem Cells ResearchSingle-cell and spatial transcriptomics

Cited by 207

The road ahead in genetics and genomics

McGuire, A. L., Gabriel, S., Tishkoff, S. A., Wonkam, A., Chakravarti, A., Furlong, E. E. M., Treutlein, B., Meissner, A., Chang, H. Y., López-Bigas, N., et al. (2020) · Nature Reviews Genetics

Science, Research, and MedicineGenetic Associations and Epidemiology

Cited by 188

The organoid cell atlas

the Human Cell Atlas ‘Biological Network’ Organoids, Bock, C., Boutros, M., Camp, J. G., Clarke, L., Clevers, H., Knoblich, J. A., Liberali, P., Regev, A., Rios, A. C., et al. (2021) · Nature Biotechnology

Single-cell and spatial transcriptomicsPluripotent Stem Cells Research

Cited by 171

Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia

Klaus, J., Kanton, S., Kyrousi, C., Ayo-Martin, A. C., Di Giaimo, R., Riesenberg, S., O’Neill, A. C., Camp, J. G., Tocco, C., Santel, M., et al. (2019) · Nature Medicine

Neurogenesis and neuroplasticity mechanismsFetal and Pediatric Neurological Disorders

Cited by 169

Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains

Khrameeva, E., Kurochkin, I., Han, D., Guijarro, P., Kanton, S., Santel, M., Qian, Z., Rong, S., Mazin, P., Sabirov, M., et al. (2020) · Genome Research

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 162

Fibroblast dedifferentiation as a determinant of successful regeneration

Lin, T.-Y., Gerber, T., Taniguchi-Sugiura, Y., Murawala, P., Hermann, S., Grosser, L., Shibata, E., Treutlein, B., & Tanaka, E. M. (2021) · Developmental Cell

Planarian Biology and ElectrostimulationDevelopmental Biology and Gene Regulation

Cited by 126

A conversation with ChatGPT on the role of computational systems biology in stem cell research

Cahan, P., & Treutlein, B. (2023) · Stem Cell Reports

Pluripotent Stem Cells ResearchGene Regulatory Network Analysis

Cited by 125

Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases

Fleck, J. S., Sanchís-Calleja, F., He, Z., Santel, M., Boyle, M. J., Camp, J. G., & Treutlein, B. (2021) · Cell Stem Cell

Single-cell and spatial transcriptomicsPluripotent Stem Cells Research

Cited by 118

A prenatal skin atlas reveals immune regulation of human skin morphogenesis

Gopee, N. H., Winheim, E., Olabi, B., Admane, C., Foster, A. R., Huang, N., Botting, R. A., Torabi, F., Sumanaweera, D., Le, A. P., et al. (2024) · Nature

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 108

Morphodynamics of human early brain organoid development

Jain, A., Gut, G., Sanchis-Calleja, F., Okamoto, R., Streib, S., He, Z., Zenk, F., Santel, M., Seimiya, M., Holtackers, R., et al. (2023) · Nature

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 73

Morphodynamics of human early brain organoid development

Jain, A., Gut, G., Sanchis-Calleja, F., Tschannen, R., He, Z., Luginbühl, N., Zenk, F., Chrisnandy, A., Streib, S., Harmel, C., et al. (2025) · Nature

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 73