Kisseleva, Tatiana

Molecular and cellular mechanisms of liver fibrosis and its regression

Kisseleva, T., & Brenner, D. (2021) · Nature Reviews Gastroenterology & Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 2,024

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

Zhong, Z., Liang, S., Sanchez-Lopez, E., He, F., Shalapour, S., Lin, X.-J., Wong, J., Ding, S., Seki, E., Schnabl, B., et al. (2018) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,208

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

Kisseleva, T., Cong, M., Paik, Y., Scholten, D., Jiang, C., Benner, C., Iwaisako, K., Moore-Morris, T., Scott, B., Tsukamoto, H., et al. (2012) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 805

Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

Meng, F., Wang, K., Aoyama, T., Grivennikov, S. I., Paik, Y., Scholten, D., Cong, M., Iwaisako, K., Liu, X., Zhang, M., et al. (2012) · Gastroenterology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 711

Origin of myofibroblasts in the fibrotic liver in mice

Iwaisako, K., Jiang, C., Zhang, M., Cong, M., Moore-Morris, T. J., Park, T. J., Liu, X., Xu, J., Wang, P., Paik, Y.-H., et al. (2014) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 535

Fructose stimulated de novo lipogenesis is promoted by inflammation

Todoric, J., Di Caro, G., Reibe, S., Henstridge, D. C., Green, C. R., Vrbanac, A., Ceteci, F., Conche, C., McNulty, R., Shalapour, S., et al. (2020) · Nature Metabolism

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 328

Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus

Llorente, C., Jepsen, P., Inamine, T., Wang, L., Bluemel, S., Wang, H. J., Loomba, R., Bajaj, J. S., Schubert, M. L., Sikaroodi, M., et al. (2017) · Nature Communications

Gut microbiota and healthAlcohol Consumption and Health Effects

Cited by 257

Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis

Gao, H., Jin, Z., Bandyopadhyay, G., Wang, G., Zhang, D., Rocha, K. C. E., Liu, X., Zhao, H., Kisseleva, T., Brenner, D. A., et al. (2022) · Cell Metabolism

Liver Disease Diagnosis and TreatmentIron Metabolism and Disorders

Cited by 224

The origin of fibrogenic myofibroblasts in fibrotic liver

Kisseleva, T. (2017) · Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 224

IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease

Ma, H.-Y., Yamamoto, G., Xu, J., Liu, X., Karin, D., Kim, J. Y., Alexandrov, L. B., Koyama, Y., Nishio, T., Benner, C., et al. (2020) · Journal of Hepatology

Liver physiology and pathologyHepatocellular Carcinoma Treatment and Prognosis

Cited by 216

An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis

Wang, S., Li, K., Pickholz, E., Dobie, R., Matchett, K. P., Henderson, N. C., Carrico, C., Driver, I., Borch Jensen, M., Chen, L., et al. (2023) · Science Translational Medicine

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 176

Sphingosine kinase 1 promotes liver fibrosis by preventing miR‐19b‐3p‐mediated inhibition of CCR2

Lan, T., Li, C., Yang, G., Sun, Y., Zhuang, L., Ou, Y., Li, H., Wang, G., Kisseleva, T., Brenner, D., et al. (2018) · Hepatology

Liver physiology and pathologySphingolipid Metabolism and Signaling

Cited by 153

Heterogeneity of HSCs in a Mouse Model of NASH

Rosenthal, S. B., Liu, X., Ganguly, S., Dhar, D., Pasillas, M. P., Ricciardelli, E., Li, R. Z., Troutman, T. D., Kisseleva, T., Glass, C. K., et al. (2021) · Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 145

Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2

Ganguly, S., Rosenthal, S. B., Ishizuka, K., Troutman, T. D., Rohm, T. V., Khader, N., Aleman-Muench, G., Sano, Y., Archilei, S., Soroosh, P., et al. (2024) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 145

Nadph oxidase 1 in liver macrophages promotes inflammation and tumor development in mice

Liang, S., Ma, H.-Y., Zhong, Z., Dhar, D., Liu, X., Xu, J., Koyama, Y., Nishio, T., Karin, D., Karin, G., et al. (2019) · Gastroenterology

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 92

Bile acid–activated macrophages promote biliary epithelial cell proliferation through integrin αvβ6 upregulation following liver injury

Guillot, A., Guerri, L., Feng, D., Kim, S.-J., Ahmed, Y. A., Paloczi, J., He, Y., Schuebel, K., Dai, S., Liu, F., et al. (2021) · Journal of Clinical Investigation

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 86

The Origin and Fate of Liver Myofibroblasts

Kim, H. Y., Sakane, S., Eguileor, A., Carvalho Gontijo Weber, R., Lee, W., Liu, X., Lam, K., Ishizuka, K., Rosenthal, S. B., Diggle, K., et al. (2024) · Cellular and Molecular Gastroenterology and Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 63

Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet

Ganguly, S., Muench, G. A., Shang, L., Rosenthal, S. B., Rahman, G., Wang, R., Wang, Y., Kwon, H. C., Diomino, A. M., Kisseleva, T., et al. (2021) · Cellular and Molecular Gastroenterology and Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 50

The Crosstalk between Hepatocytes, Hepatic Macrophages, and Hepatic Stellate Cells Facilitates Alcoholic Liver Disease

Kisseleva, T., & Brenner, D. A. (2019) · Cell Metabolism

Alcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment

Cited by 39

Protective effect of human serum amyloid P on CCl4-induced acute liver injury in mice

Cong, M., Zhao, W., Liu, T., Wang, P., Fan, X., Zhai, Q., Bao, X., Zhang, D., You, H., Kisseleva, T., et al. (2017) · International Journal of Molecular Medicine

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 33

Metabolic injury of hepatocytes promotes progression of NAFLD and AALD

Carvalho-Gontijo, R., Han, C., Zhang, L., Zhang, V., Hosseini, M., Mekeel, K., Schnabl, B., Loomba, R., Karin, M., Brenner, D. A., et al. (2022) · Seminars in Liver Disease

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 23

Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover

Feng, X., Zhang, S., Wang, Y., Kurlagunda, T., Sit, A., Jaishankar, P., Yang, P., Sakane, S., Park, S. Y., Wisessaowapak, C., et al. (2026) · Nature

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 2