Jacobson, David A.

Kv2.1 Ablation Alters Glucose-Induced Islet Electrical Activity, Enhancing Insulin Secretion

Jacobson, D. A., Kuznetsov, A., Lopez, J. P., Kash, S., Ämmälä, C. E., & Philipson, L. H. (2007) · Cell Metabolism

Pancreatic function and diabetesIon channel regulation and function

Cited by 180

Androgen Excess in Pancreatic β Cells and Neurons Predisposes Female Mice to Type 2 Diabetes

Navarro, G., Allard, C., Morford, J. J., Xu, W., Liu, S., Molinas, A. J. R., Butcher, S. M., Fine, N. H. F., Blandino-Rosano, M., Sure, V. N., et al. (2018) · JCI Insight

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 80

β-Cell–Specific Protein Kinase A Activation Enhances the Efficiency of Glucose Control by Increasing Acute-Phase Insulin Secretion

Kaihara, K. A., Dickson, L. M., Jacobson, D. A., Tamarina, N., Roe, M. W., Philipson, L. H., & Wicksteed, B. (2013) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 80

Ion channels and regulation of insulin secretion in human β-cells: a computational systems analysis

Fridlyand, L. E., Jacobson, D. A., & Philipson, L. H. (2013) · Islets

Pancreatic function and diabetesIon channel regulation and function

Cited by 78

Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses: Kv and K Ca regulation of islet electrical activity

Jacobson, D. A., Mendez, F., Thompson, M., Torres, J., Cochet, O., & Philipson, L. H. (2010) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 73

Type 2 Diabetes–Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis

Vierra, N. C., Dadi, P. K., Jeong, I., Dickerson, M., Powell, D. R., & Jacobson, D. A. (2015) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 71

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Fine, N. H. F., Doig, C. L., Elhassan, Y. S., Vierra, N. C., Marchetti, P., Bugliani, M., Nano, R., Piemonti, L., Rutter, G. A., Jacobson, D. A., et al. (2018) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 61

Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction

Perfitt, T. L., Wang, X., Dickerson, M. T., Stephenson, J. R., Nakagawa, T., Jacobson, D. A., & Colbran, R. J. (2020) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 54

Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males

Walker, E. M., Cha, J., Tong, X., Guo, M., Liu, J.-H., Yu, S., Iacovazzo, D., Mauvais-Jarvis, F., Flanagan, S. E., Korbonits, M., et al. (2021) · Cell Reports

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 48

TASK-1 Potassium Channels Limit Pancreatic α-Cell Calcium Influx and Glucagon Secretion

Dadi, P. K., Luo, B., Vierra, N. C., & Jacobson, D. A. (2015) · Molecular Endocrinology

Pancreatic function and diabetesIon channel regulation and function

Cited by 40