Choi, Augustine M.K.

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

Moon, J.-S., Lee, S., Park, M.-A., Siempos, I. I., Haslip, M., Lee, P. J., Yun, M., Kim, C. K., Howrylak, J., Ryter, S. W., et al. (2015) · Journal of Clinical Investigation

Inflammasome and immune disordersImmune Response and Inflammation

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Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.

Lee, S.-J., Smith, A., Guo, L., Alastalo, T.-P., Li, M., Sawada, H., Liu, X., Chen, Z.-H., Ifedigbo, E., Jin, Y., et al. (2011) · American Journal of Respiratory and Critical Care Medicine

Pulmonary Hypertension Research and TreatmentsAutophagy in Disease and Therapy

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Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase–Dependent Nitric Oxide Generation

Zuckerbraun, B. S., Shiva, S., Ifedigbo, E., Mathier, M. A., Mollen, K. P., Rao, J., Bauer, P. M., Choi, J. J. W., Curtis, E., Choi, A. M. K., et al. (2010) · Circulation

Pulmonary Hypertension Research and TreatmentsNitric Oxide and Endothelin Effects

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Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis

Bhatia, D., Chung, K.-P., Nakahira, K., Patino, E., Rice, M. C., Torres, L. K., Muthukumar, T., Choi, A. M. K., Akchurin, O. M., & Choi, M. E. (2019) · JCI Insight

Autophagy in Disease and TherapyChronic Kidney Disease and Diabetes

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Characterization of macroautophagic flux in vivo using a leupeptin-based assay

Haspel, J., Shaik, R. S., Ifedigbo, E., Nakahira, K., Dolinay, T., Englert, J. A., & Choi, A. M. K. (2011) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

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Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/Bid Pathway

Wang, X., Ryter, S. W., Dai, C., Tang, Z.-L., Watkins, S. C., Yin, X.-M., Song, R., & Choi, A. M. K. (2003) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

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Glucose Transporter 1–Dependent Glycolysis Is Increased during Aging-Related Lung Fibrosis, and Phloretin Inhibits Lung Fibrosis

Cho, S. J., Moon, J.-S., Lee, C.-M., Choi, A. M. K., & Stout-Delgado, H. W. (2017) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisMetabolism, Diabetes, and Cancer

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Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits

Chiang, N., Shinohara, M., Dalli, J., Mirakaj, V., Kibi, M., Choi, A. M. K., & Serhan, C. N. (2013) · The Journal of Immunology

Heme Oxygenase-1 and Carbon MonoxidePhagocytosis and Immune Regulation

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Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

Tam, J. M., Mansour, M. K., Khan, N. S., Seward, M., Puranam, S., Tanne, A., Sokolovska, A., Becker, C. E., Acharya, M., Baird, M. A., et al. (2014) · The Journal of Infectious Diseases

Autophagy in Disease and TherapyAntifungal resistance and susceptibility

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Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice

Zhou, J.-S., Li, Z.-Y., Xu, X.-C., Zhao, Y., Wang, Y., Chen, H.-P., Zhang, M., Wu, Y.-F., Lai, T.-W., Di, C.-H., et al. (2020) · European Respiratory Journal

Chronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseases

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Autophagy in Pulmonary Diseases

Nakahira, K., Pabon Porras, M. A., & Choi, A. M. K. (2016) · American Journal of Respiratory and Critical Care Medicine

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Cyr61 Protects against Hyperoxia-Induced Cell Death via Akt Pathway in Pulmonary Epithelial Cells

Jin, Y., Kim, H. P., Ifedigbo, E., Lau, L. F., & Choi, A. M. K. (2005) · American Journal of Respiratory Cell and Molecular Biology

Connective Tissue Growth Factor ResearchNeonatal Respiratory Health Research

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Deacetylation of p53 induces autophagy by suppressing Bmf expression

Contreras, A. U., Mebratu, Y., Delgado, M., Montano, G., Hu, C.-A. A., Ryter, S. W., Choi, A. M. K., Lin, Y., Xiang, J., Chand, H., et al. (2013) · Journal of Cell Biology

Autophagy in Disease and TherapyCell death mechanisms and regulation

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