Choi, Augustine M.K.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

Nakahira, K., Haspel, J. A., Rathinam, V. A. K., Lee, S.-J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., et al. (2011) · Nature Immunology

Inflammasome and immune disordersAutophagy in Disease and Therapy

Cited by 3,049

Autophagy in Human Health and Disease

Choi, A. M. K., Ryter, S. W., & Levine, B. (2013) · New England Journal of Medicine

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,583

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

Otterbein, L. E., Bach, F. H., Alam, J., Soares, M., Tao Lu, H., Wysk, M., Davis, R. J., Flavell, R. A., & Choi, A. M. K. (2000) · Nature Medicine

Heme Oxygenase-1 and Carbon MonoxideHemoglobin structure and function

Cited by 2,153

Molecular definitions of autophagy and related processes

Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cecconi, F., Choi, A. M., Chu, C. T., Codogno, P., Colombo, M. I., et al. (2017) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,646

Autophagy in major human diseases

Klionsky, D. J., Petroni, G., Amaravadi, R. K., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cadwell, K., Cecconi, F., Choi, A. M. K., et al. (2021) · The EMBO Journal

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,585

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

Garrett-Bakelman, F. E., Darshi, M., Green, S. J., Gur, R. C., Lin, L., Macias, B. R., McKenna, M. J., Meydan, C., Mishra, T., Nasrini, J., et al. (2019) · Science

Spaceflight effects on biologySpace exploration and regulation

Cited by 1,128

Heme Oxygenase-1: Function, Regulation, and Implication of a Novel Stress-Inducible Protein in Oxidant-Induced Lung Injury

Choi, A. M., & Alam, J. (1996) · American Journal of Respiratory Cell and Molecular Biology

Heme Oxygenase-1 and Carbon MonoxideHemoglobin structure and function

Cited by 1,126

Carbon Monoxide Generated by Heme Oxygenase 1 Suppresses Endothelial Cell Apoptosis

Brouard, S., Otterbein, L. E., Anrather, J., Tobiasch, E., Bach, F. H., Choi, A. M. K., & Soares, M. P. (2000) · The Journal of Experimental Medicine

Heme Oxygenase-1 and Carbon MonoxideHemoglobin structure and function

Cited by 984

Paneth cells as a site of origin for intestinal inflammation

Adolph, T. E., Tomczak, M. F., Niederreiter, L., Ko, H.-J., Böck, J., Martinez-Naves, E., Glickman, J. N., Tschurtschenthaler, M., Hartwig, J., Hosomi, S., et al. (2013) · Nature

Inflammatory Bowel DiseaseAutophagy in Disease and Therapy

Cited by 732

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

Mizumura, K., Cloonan, S. M., Nakahira, K., Bhashyam, A. R., Cervo, M., Kitada, T., Glass, K., Owen, C. A., Mahmood, A., Washko, G. R., et al. (2014) · Journal of Clinical Investigation

Autophagy in Disease and TherapyChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 611

Autophagy and inflammation in chronic respiratory disease

Racanelli, A. C., Kikkers, S. A., Choi, A. M. K., & Cloonan, S. M. (2018) · Autophagy

Autophagy in Disease and TherapyAsthma and respiratory diseases

Cited by 547

Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance

Ryter, S. W., Otterbein, L. E., Morse, D., & Choi, A. M. K. (2002) · Molecular and Cellular Biochemistry

Heme Oxygenase-1 and Carbon MonoxideHemoglobin structure and function

Cited by 497

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

Chen, Z.-H., Kim, H. P., Sciurba, F. C., Lee, S.-J., Feghali-Bostwick, C., Stolz, D. B., Dhir, R., Landreneau, R. J., Schuchert, M. J., Yousem, S. A., et al. (2008) · PLoS ONE

Autophagy in Disease and TherapyChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 459

Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation

Nakahira, K., Kyung, S.-Y., Rogers, A. J., Gazourian, L., Youn, S., Massaro, A. F., Quintana, C., Osorio, J. C., Wang, Z., Zhao, Y., et al. (2013) · PLoS Medicine

Sepsis Diagnosis and TreatmentMitochondrial Function and Pathology

Cited by 445

Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis

Wang, X. M., Zhang, Y., Kim, H. P., Zhou, Z., Feghali-Bostwick, C. A., Liu, F., Ifedigbo, E., Xu, X., Oury, T. D., Kaminski, N., et al. (2006) · The Journal of Experimental Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisCaveolin-1 and cellular processes

Cited by 397

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

Chen, Z.-H., Lam, H. C., Jin, Y., Kim, H.-P., Cao, J., Lee, S.-J., Ifedigbo, E., Parameswaran, H., Ryter, S. W., & Choi, A. M. K. (2010) · Proceedings of the National Academy of Sciences

Chronic Obstructive Pulmonary Disease (COPD) ResearchAutophagy in Disease and Therapy

Cited by 380

Mitochondria in lung disease

Cloonan, S. M., & Choi, A. M. K. (2016) · Journal of Clinical Investigation

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 322

Histone deacetylase 6–mediated selective autophagy regulates COPD-associated cilia dysfunction

Lam, H. C., Cloonan, S. M., Bhashyam, A. R., Haspel, J. A., Singh, A., Sathirapongsasuti, J. F., Cervo, M., Yao, H., Chung, A. L., Mizumura, K., et al. (2013) · Journal of Clinical Investigation

Autophagy in Disease and TherapyCystic Fibrosis Research Advances

Cited by 307

RETRACTED ARTICLE: NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages

Moon, J.-S., Nakahira, K., Chung, K.-P., DeNicola, G. M., Koo, M. J., Pabón, M. A., Rooney, K. T., Yoon, J.-H., Ryter, S. W., Stout-Delgado, H., et al. (2016) · Nature Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 291

Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3

Zhang, X., Shan, P., Otterbein, L. E., Alam, J., Flavell, R. A., Davis, R. J., Choi, A. M. K., & Lee, P. J. (2003) · Journal of Biological Chemistry

Heme Oxygenase-1 and Carbon MonoxideCell death mechanisms and regulation

Cited by 288

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

Moon, J.-S., Lee, S., Park, M.-A., Siempos, I. I., Haslip, M., Lee, P. J., Yun, M., Kim, C. K., Howrylak, J., Ryter, S. W., et al. (2015) · Journal of Clinical Investigation

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 238