Loscalzo, Joseph

Cellular glutathione peroxidase deficiency and endothelial dysfunction

Forgione, M. A., Weiss, N., Heydrick, S., Cap, A., Klings, E. S., Bierl, C., Eberhardt, R. T., Farber, H. W., & Loscalzo, J. (2002) · American Journal of Physiology-Heart and Circulatory Physiology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 199

Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center

Eberly, L. A., Richterman, A., Beckett, A. G., Wispelwey, B., Marsh, R. H., Cleveland Manchanda, E. C., Chang, C. Y., Glynn, R. J., Brooks, K. C., Boxer, R., et al. (2019) · Circulation: Heart Failure

Heart Failure Treatment and ManagementHealth disparities and outcomes

Cited by 189

Glutathione Peroxidase-1 Regulates Mitochondrial Function to Modulate Redox-dependent Cellular Responses

Handy, D. E., Lubos, E., Yang, Y., Galbraith, J. D., Kelly, N., Zhang, Y.-Y., Leopold, J. A., & Loscalzo, J. (2009) · Journal of Biological Chemistry

Redox biology and oxidative stressSelenium in Biological Systems

Cited by 187

Glutathione Peroxidase-3 Deficiency Promotes Platelet-Dependent Thrombosis In Vivo

Jin, R. C., Mahoney, C. E., (Coleman) Anderson, L., Ottaviano, F., Croce, K., Leopold, J. A., Zhang, Y.-Y., Tang, S.-S., Handy, D. E., & Loscalzo, J. (2011) · Circulation

Platelet Disorders and TreatmentsBlood Coagulation and Thrombosis Mechanisms

Cited by 186

Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis.

Freedman, J. E., Loscalzo, J., Benoit, S. E., Valeri, C. R., Barnard, M. R., & Michelson, A. D. (1996) · Journal of Clinical Investigation

Platelet Disorders and TreatmentsNitric Oxide and Endothelin Effects

Cited by 171

Candidal infection in the central nervous system

Lipton, S. A., Hickey, W. F., Morris, J. H., & Loscalzo, J. (1984) · The American Journal of Medicine

Antifungal resistance and susceptibilityFungal Infections and Studies

Cited by 157

S -nitrosoprotein formation and localization in endothelial cells

Yang, Y., & Loscalzo, J. (2005) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 141

Regulation of the protein disulfide proteome by mitochondria in mammalian cells

Yang, Y., Song, Y., & Loscalzo, J. (2007) · Proceedings of the National Academy of Sciences

Redox biology and oxidative stressMitochondrial Function and Pathology

Cited by 129

Network medicine framework for identifying drug-repurposing opportunities for COVID-19

Morselli Gysi, D., do Valle, Í., Zitnik, M., Ameli, A., Gan, X., Varol, O., Ghiassian, S. D., Patten, J. J., Davey, R. A., Loscalzo, J., et al. (2021) · Proceedings of the National Academy of Sciences

Computational Drug Discovery MethodsSARS-CoV-2 and COVID-19 Research

Cited by 107

Network Medicine in Pathobiology

Lee, L. Y.-H., & Loscalzo, J. (2019) · The American Journal of Pathology

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 95

Plasma Glutathione Peroxidase Deficiency and Platelet Insensitivity to Nitric Oxide in Children With Familial Stroke

Kenet, G., Freedman, J., Shenkman, B., Regina, E., Brok-Simoni, F., Holzman, F., Vavva, F., Brand, N., Michelson, A., Trolliet, M., et al. (1999) · Arteriosclerosis, Thrombosis, and Vascular Biology

Platelet Disorders and TreatmentsBlood Coagulation and Thrombosis Mechanisms

Cited by 83

Primer on Medical Genomics Part XIV: Introduction to Systems Biology—A New Approach to Understanding Disease and Treatment

Morel, N. M., Holland, J. M., van der Greef, J., Marple, E. W., Clish, C., Loscalzo, J., & Naylor, S. (2004) · Mayo Clinic Proceedings

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 71

Decoding the Foodome: Molecular Networks Connecting Diet and Health

Menichetti, G., Barabási, A.-L., & Loscalzo, J. (2024) · Annual Review of Nutrition

Nutrition, Genetics, and DiseaseNutritional Studies and Diet

Cited by 32

Determinants of drug-target interactions at the single cell level

Elgart, V., Lin, J.-R., & Loscalzo, J. (2018) · PLOS Computational Biology

Diffusion and Search DynamicsComputational Drug Discovery Methods

Cited by 27

Commonalities across computational workflows for uncovering explanatory variants in undiagnosed cases

Kobren, S. N., Baldridge, D., Velinder, M., Krier, J. B., LeBlanc, K., Esteves, C., Pusey, B. N., Züchner, S., Blue, E., Lee, H., et al. (2021) · Genetics in Medicine

Genomics and Rare DiseasesGenomics and Phylogenetic Studies

Cited by 27