Brais, Lauren K.

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

Raghavan, S., Winter, P. S., Navia, A. W., Williams, H. L., DenAdel, A., Lowder, K. E., Galvez-Reyes, J., Kalekar, R. L., Mulugeta, N., Kapner, K. S., et al. (2021) · Cell

Pancreatic and Hepatic Oncology ResearchSingle-cell and spatial transcriptomics

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Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine

Aguirre, A. J., Nowak, J. A., Camarda, N. D., Moffitt, R. A., Ghazani, A. A., Hazar-Rethinam, M., Raghavan, S., Kim, J., Brais, L. K., Ragon, D., et al. (2018) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

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A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories

Placido, D., Yuan, B., Hjaltelin, J. X., Zheng, C., Haue, A. D., Chmura, P. J., Yuan, C., Kim, J., Umeton, R., Antell, G., et al. (2023) · Nature Medicine

Machine Learning in HealthcarePancreatic and Hepatic Oncology Research

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Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Klein, A. P., Wolpin, B. M., Risch, H. A., Stolzenberg-Solomon, R. Z., Mocci, E., Zhang, M., Canzian, F., Childs, E. J., Hoskins, J. W., Jermusyk, A., et al. (2018) · Nature Communications

Pancreatic and Hepatic Oncology ResearchGenetic Associations and Epidemiology

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Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma

Qian, Z. R., Rubinson, D. A., Nowak, J. A., Morales-Oyarvide, V., Dunne, R. F., Kozak, M. M., Welch, M. W., Brais, L. K., Da Silva, A., Li, T., et al. (2018) · JAMA Oncology

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

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Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer

Yurgelun, M. B., Chittenden, A. B., Morales-Oyarvide, V., Rubinson, D. A., Dunne, R. F., Kozak, M. M., Qian, Z. R., Welch, M. W., Brais, L. K., Da Silva, A., et al. (2019) · Genetics in Medicine

Pancreatic and Hepatic Oncology ResearchBRCA gene mutations in cancer

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Lead-time trajectory of CA19-9 as an anchor marker for pancreatic cancer early detection

Fahrmann, J. F., Schmidt, C. M., Mao, X., Irajizad, E., Loftus, M., Zhang, J., Patel, N., Vykoukal, J., Dennison, J. B., Long, J. P., et al. (2021) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

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Diabetes, weight change, and pancreatic cancer risk

Yuan, C., Babic, A., Khalaf, N., Nowak, J. A., Brais, L. K., Rubinson, D. A., Ng, K., Aguirre, A. J., Pandharipande, P. V., Fuchs, C. S., et al. (2020) · JAMA Oncology

Pancreatic and Hepatic Oncology ResearchCancer Risks and Factors

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Altered exocrine function can drive adipose wasting in early pancreatic cancer

Danai, L. V., Babic, A., Rosenthal, M. H., Dennstedt, E. A., Muir, A., Lien, E. C., Mayers, J. R., Tai, K., Lau, A. N., Jones-Sali, P., et al. (2018) · Nature

Pancreatic and Hepatic Oncology ResearchNutrition and Health in Aging

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Abstract PR-006: Spatially resolved, single cell assessment of pancreatic ductal adenocarcinoma expression subtypes reveals mixed and hybrid basal-classical marker expression with prognostic significance and discrete spatial localization

Williams, H. L., Zhang, J., Raghavan, S., Winter, P. S., Kapner, K., Vayrynen, S., Costa, A. D., Yuan, C., Lau, M. C., Morales-Oyarvide, V., et al. (2020) · Cancer Research

Pancreatic and Hepatic Oncology ResearchSingle-cell and spatial transcriptomics

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