Davis, Roger J.

JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

Ventura, J.-J., Cogswell, P., Flavell, R. A., Baldwin, A. S., & Davis, R. J. (2004) · Genes & Development

Cell death mechanisms and regulationNF-κB Signaling Pathways

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Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3

Zhang, X., Shan, P., Otterbein, L. E., Alam, J., Flavell, R. A., Davis, R. J., Choi, A. M. K., & Lee, P. J. (2003) · Journal of Biological Chemistry

Heme Oxygenase-1 and Carbon MonoxideCell death mechanisms and regulation

Cited by 288

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

Kelkar, N., Gupta, S., Dickens, M., & Davis, R. J. (2000) · Molecular and Cellular Biology

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 281

WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans

Rocheleau, C. E., Yasuda, J., Shin, T. H., Lin, R., Sawa, H., Okano, H., Priess, J. R., Davis, R. J., & Mello, C. C. (1999) · Cell

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

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Requirement of the JIP1 scaffold protein for stress-induced JNK activation

Whitmarsh, A. J., Kuan, C.-Y., Kennedy, N. J., Kelkar, N., Haydar, T. F., Mordes, J. P., Appel, M., Rossini, A. A., Jones, S. N., Flavell, R. A., et al. (2001) · Genes & Development

Protein Kinase Regulation and GTPase SignalingNF-κB Signaling Pathways

Cited by 238

Multisite Phosphorylation Regulates Bim Stability and Apoptotic Activity

Hübner, A., Barrett, T., Flavell, R. A., & Davis, R. J. (2008) · Molecular Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 228

Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity

Gao, Z., Zhang, J., Kheterpal, I., Kennedy, N., Davis, R. J., & Ye, J. (2011) · Journal of Biological Chemistry

Sirtuins and Resveratrol in MedicineLiver Disease Diagnosis and Treatment

Cited by 187

c-Jun Is a JNK-independent Coactivator of the PU.1 Transcription Factor

Behre, G., Whitmarsh, A. J., Coghlan, M. P., Hoang, T., Carpenter, C. L., Zhang, D.-E., Davis, R. J., & Tenen, D. G. (1999) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 180

cJun NH2-terminal kinase 1 (JNK1): Roles in metabolic regulation of insulin resistance

Sabio, G., & Davis, R. J. (2010) · Trends in Biochemical Sciences

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 170

Mcl-1 Integrates the Opposing Actions of Signaling Pathways That Mediate Survival and Apoptosis

Morel, C., Carlson, S. M., White, F. M., & Davis, R. J. (2009) · Molecular and Cellular Biology

Cell death mechanisms and regulationUbiquitin and proteasome pathways

Cited by 143

MOM-4, a MAP Kinase Kinase Kinase–Related Protein, Activates WRM-1/LIT-1 Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans

Shin, T. H., Yasuda, J., Rocheleau, C. E., Lin, R., Soto, M., Bei, Y., Davis, R. J., & Mello, C. C. (1999) · Molecular Cell

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 123

An essential role of the JIP1 scaffold protein for JNK activation in adipose tissue

Jaeschke, A., Czech, M. P., & Davis, R. J. (2004) · Genes & Development

Adipokines, Inflammation, and Metabolic DiseasesProtein Tyrosine Phosphatases

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JNK regulates muscle remodeling via myostatin/SMAD inhibition

Lessard, S. J., MacDonald, T. L., Pathak, P., Han, M. S., Coffey, V. G., Edge, J., Rivas, D. A., Hirshman, M. F., Davis, R. J., & Goodyear, L. J. (2018) · Nature Communications

Muscle Physiology and DisordersMuscle metabolism and nutrition

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Targeting dendritic cell signaling to regulate the response to immunization

Escors, D., Lopes, L., Lin, R., Hiscott, J., Akira, S., Davis, R. J., & Collins, M. K. (2008) · Blood

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 116

Analysis and Correction of Inappropriate Image Duplication: the Molecular and Cellular Biology Experience

Bik, E. M., Fang, F. C., Kullas, A. L., Davis, R. J., & Casadevall, A. (2018) · Molecular and Cellular Biology

Academic integrity and plagiarismAcademic Publishing and Open Access

Cited by 55

A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

Han, M. S., Perry, R. J., Camporez, J.-P., Scherer, P. E., Shulman, G. I., Gao, G., & Davis, R. J. (2021) · Genes & Development

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

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Requirement of JIP scaffold proteins for NMDA-mediated signal transduction

Kennedy, N. J., Martin, G., Ehrhardt, A. G., Cavanagh-Kyros, J., Kuan, C.-Y., Rakic, P., Flavell, R. A., Treistman, S. N., & Davis, R. J. (2007) · Genes & Development

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 40

Airway epithelial specific deletion of Jun-N-terminal kinase 1 attenuates pulmonary fibrosis in two independent mouse models

van der Velden, J. L., Alcorn, J. F., Chapman, D. G., Lundblad, L. K. A., Irvin, C. G., Davis, R. J., Butnor, K., & Janssen-Heininger, Y. M. W. (2020) · PLOS ONE

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisPulmonary Hypertension Research and Treatments

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Requirement of JIP1-mediated c-Jun N-terminal kinase activation for obesity-induced insulin resistance

Morel, C., Standen, C. L., Jung, D. Y., Gray, S., Ong, H., Flavell, R. A., Kim, J. K., & Davis, R. J. (2010) · Molecular and Cellular Biology

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

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