Collinge, John

Convergent genetic and expression data implicate immunity in Alzheimer's disease

International Genomics of Alzheimer's Disease Consortium (IGAP), Jones, L., Lambert, J., Wang, L., Choi, S., Harold, D., Vedernikov, A., Escott‐Price, V., Stone, T., Richards, A., et al. (2015) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 199

Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

Purro, S. A., Farrow, M. A., Linehan, J., Nazari, T., Thomas, D. X., Chen, Z., Mengel, D., Saito, T., Saido, T., Rudge, P., et al. (2018) · Nature

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 191

CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro

van der Zee, J., Urwin, H., Engelborghs, S., Bruyland, M., Vandenberghe, R., Dermaut, B., De Pooter, T., Peeters, K., Santens, P., De Deyn, P. P., et al. (2008) · Human Molecular Genetics

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 167

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

Swarup, V., Hinz, F. I., Rexach, J. E., Noguchi, K.-I., Toyoshiba, H., Oda, A., Hirai, K., Sarkar, A., Seyfried, N. T., Cheng, C., et al. (2019) · Nature Medicine

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 136

Crystal structure of human prion protein bound to a therapeutic antibody

Antonyuk, S. V., Trevitt, C. R., Strange, R. W., Jackson, G. S., Sangar, D., Batchelor, M., Cooper, S., Fraser, C., Jones, S., Georgiou, T., et al. (2009) · Proceedings of the National Academy of Sciences

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 124

R47H TREM2 variant increases risk of typical early‐onset Alzheimer's disease but not of prion or frontotemporal dementia

Slattery, C. F., Beck, J. A., Harper, L., Adamson, G., Abdi, Z., Uphill, J., Campbell, T., Druyeh, R., Mahoney, C. J., Rohrer, J. D., et al. (2014) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 119

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

Nicoll, A. J., Panico, S., Freir, D. B., Wright, D., Terry, C., Risse, E., Herron, C. E., O’Malley, T., Wadsworth, J. D. F., Farrow, M. A., et al. (2013) · Nature Communications

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 119

Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice

Ghazi-Noori, S., Froud, K. E., Mizielinska, S., Powell, C., Smidak, M., Fernandez de Marco, M., O’Malley, C., Farmer, M., Parkinson, N., Fisher, E. M. C., et al. (2012) · Brain

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 115

A clinical study of kuru patients with long incubation periods at the end of the epidemic in Papua New Guinea

Collinge, J., Whitfield, J., McKintosh, E., Frosh, A., Mead, S., Hill, A. F., Brandner, S., Thomas, D., & Alpers, M. P. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences

Prion Diseases and Protein MisfoldingAmyloidosis: Diagnosis, Treatment, Outcomes

Cited by 110

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology

The FReJA consortium, Clayton, E. L., Mizielinska, S., Edgar, J. R., Nielsen, T. T., Marshall, S., Norona, F. E., Robbins, M., Damirji, H., Holm, I. E., et al. (2015) · Acta Neuropathologica

Lysosomal Storage Disorders ResearchAlzheimer's disease research and treatments

Cited by 96

Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity

Klyubin, I., Nicoll, A. J., Khalili-Shirazi, A., Farmer, M., Canning, S., Mably, A., Linehan, J., Brown, A., Wakeling, M., Brandner, S., et al. (2014) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 74

Inhibition of Proteinase K Activity by Copper(II) Ions,

Stone, L. A., Jackson, G. S., Collinge, J., Wadsworth, J. D. F., & Clarke, A. R. (2007) · Biochemistry

Prion Diseases and Protein MisfoldingProtease and Inhibitor Mechanisms

Cited by 43

Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipoprotein E locus

Houlden, H., Crook, R., Hardy, J., Roques, P., Collinge, J., & Rossor, M. (1994) · Neuroscience Letters

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 38

Mortuary rites of the South Fore and kuru

Whitfield, J. T., Pako, W. H., Collinge, J., & Alpers, M. P. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences

Prion Diseases and Protein MisfoldingDeath, Funerary Practices, and Mourning

Cited by 36

Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Kunkle, B., Grenier-Boley, B., Sims, R., Bis, J., Naj, A., Boland, A., Vronskaya, M., van der Lee, S., Amlie-Wolf, A., Bellenguez, C., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 35

Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation

Clayton, E. L., Mancuso, R., Nielsen, T. T., Mizielinska, S., Holmes, H., Powell, N., Norona, F., Overgaard Larsen, J., Milioto, C., Wilson, K. M., et al. (2017) · Human Molecular Genetics

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 32

Lessons of kuru research: background to recent studies with some personal reflections

Collinge, J. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences

Prion Diseases and Protein MisfoldingAmyloidosis: Diagnosis, Treatment, Outcomes

Cited by 25

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

Mengel, D., Mok, T. H., Nihat, A., Liu, W., Rissman, R. A., Galasko, D., Zetterberg, H., Mead, S., Collinge, J., & Walsh, D. M. (2021) · Cells

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 12

Cultural factors that affected the spatial and temporal epidemiology of kuru

Whitfield, J. T., Pako, W. H., Collinge, J., & Alpers, M. P. (2017) · Royal Society Open Science

Prion Diseases and Protein MisfoldingLanguage and cultural evolution

Cited by 8