Nilsson, Jakob

A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

Hertz, E. P. T., Kruse, T., Davey, N. E., López-Méndez, B., Sigurðsson, J. O., Montoya, G., Olsen, J. V., & Nilsson, J. (2016) · Molecular Cell

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 282

The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP

Askjaer, P., Jensen, T. H., Nilsson, J., Englmeier, L., & Kjems, J. (1998) · Journal of Biological Chemistry

Nuclear Structure and FunctionRNA Research and Splicing

Cited by 219

Direct binding between BubR1 and B56–PP2A phosphatase complexes regulate mitotic progression

Kruse, T., Zhang, G., Larsen, M. S. Y., Lischetti, T., Streicher, W., Kragh Nielsen, T., Bjørn, S. P., & Nilsson, J. (2013) · Journal of Cell Science

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 205

Structures of modified eEF2·80S ribosome complexes reveal the role of GTP hydrolysis in translocation

Taylor, D. J., Nilsson, J., Merrill, A. R., Andersen, G. R., Nissen, P., & Frank, J. (2007) · The EMBO Journal

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 193

Mechanisms of site‐specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits

Kruse, T., Gnosa, S. P., Nasa, I., Garvanska, D. H., Hein, J. B., Nguyen, H., Samsøe‐Petersen, J., Lopez‐Mendez, B., Hertz, E. P. T., Schwarz, J., et al. (2020) · The EMBO Journal

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 97

The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30

Kruse, T., Biedenkopf, N., Hertz, E. P. T., Dietzel, E., Stalmann, G., López-Méndez, B., Davey, N. E., Nilsson, J., & Becker, S. (2018) · Molecular Cell

Viral Infections and Outbreaks ResearchVirology and Viral Diseases

Cited by 92

A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment

Wang, X., Garvanska, D. H., Nasa, I., Ueki, Y., Zhang, G., Kettenbach, A. N., Peti, W., Nilsson, J., & Page, R. (2020) · eLife

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 53

Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

Pavic, K., Gupta, N., Omella, J. D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J. A., Höfflin, N., Okkeri, J., Wang, Z., et al. (2023) · Nature Communications

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 36

Chemogenetic profiling reveals PP2A‐independent cytotoxicity of proposed PP2A activators iHAP1 and DT‐061

Vit, G., Duro, J., Rajendraprasad, G., Hertz, E. P. T., Holland, L. K. K., Weisser, M. B., McEwan, B. C., Lopez‐Mendez, B., Sotelo‐Parrilla, P., Jeyaprakash, A. A., et al. (2022) · The EMBO Journal

Protein Tyrosine PhosphatasesPI3K/AKT/mTOR signaling in cancer

Cited by 34

Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting

Vit, G., Duro, J., Rajendraprasad, G., Hertz, E. P. T., Kauffeldt Holland, L. K., Weisser, M. B., McEwan, B. C., Lopez-Mendez, B., Montoya, G., Mailand, N., et al. (2021) · The EMBO Journal

Protein Tyrosine PhosphatasesPI3K/AKT/mTOR signaling in cancer

Cited by 33

Substrate recognition principles for the PP2A-B55 protein phosphatase

Kruse, T., Garvanska, D. H., Varga, J., Garland, W., McEwan, B., Hein, J. B., Weisser, M. B., Puy, I. B., Chan, C. B., Parrila, P. S., et al. (2024) · Science Advances

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 26

Substrate recognition principles for the PP2A-B55 protein phosphatase

Kruse, T., Garvanska, D. H., Varga, J. K., Garland, W., McEwan, B. C., Hein, J. B., Weisser, M. B., Benavides-Puy, I., Chan, C. B., Sotelo-Parrilla, P., et al. (2024) · Science Advances

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 26

A highly conserved binding pocket on PP2A-B56 is required for shugoshin binding and cohesion protection

Ueki, Y., Hadders, M., Weisser, M. B., Nasa, I., Gupta, T., Hertz, E. T., Kruse, T., Montoya, G., Jeyaprakash, A. A., Kettenbach, A., et al. (2020) · EMBO Reports

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 16

A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis

Ueki, Y., Hadders, M. A., Weisser, M. B., Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, E. P. T., Kruse, T., Montoya, G., et al. (2021) · The EMBO Reports

Microtubule and mitosis dynamicsGenomics and Chromatin Dynamics

Cited by 16