Hardiman, Orla

Amyotrophic lateral sclerosis

Kiernan, M. C., Vucic, S., Cheah, B. C., Turner, M. R., Eisen, A., Hardiman, O., Burrell, J. R., & Zoing, M. C. (2011) · The Lancet

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 2,603

Prognostic factors in ALS: A critical review

Chiò, A., Logroscino, G., Hardiman, O., Swingler, R., Mitchell, D., Beghi, E., Traynor, B. G., & On Behalf of the Eurals Consortium (2009) · Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 1,172

EFNS guidelines on the Clinical Management of Amyotrophic Lateral Sclerosis (MALS) - revised report of an EFNS task force

The EFNS Task Force on Diagnosis and Management of Amyotrophic Lateral Sclerosis:, Andersen, P. M., Abrahams, S., Borasio, G. D., de Carvalho, M., Chio, A., Van Damme, P., Hardiman, O., Kollewe, K., Morrison, K. E., et al. (2012) · European Journal of Neurology

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 1,117

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Kappos, L., Bar-Or, A., Cree, B. A. C., Fox, R. J., Giovannoni, G., Gold, R., Vermersch, P., Arnold, D. L., Arnould, S., Scherz, T., et al. (2018) · The Lancet

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 942

Incidence of amyotrophic lateral sclerosis in Europe

Logroscino, G., Traynor, B. J., Hardiman, O., Chio, A., Mitchell, D., Swingler, R. J., Millul, A., Benn, E., Beghi, E., & EURALS, F. (2010) · Journal of Neurology, Neurosurgery & Psychiatry

Amyotrophic Lateral Sclerosis ResearchAmyloidosis: Diagnosis, Treatment, Outcomes

Cited by 772

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

van Rheenen, W., van der Spek, R. A. A., Bakker, M. K., van Vugt, J. J. F. A., Hop, P. J., Zwamborn, R. A. J., de Klein, N., Westra, H.-J., Bakker, O. B., Deelen, P., et al. (2021) · Nature Genetics

Amyotrophic Lateral Sclerosis ResearchGenetic Associations and Epidemiology

Cited by 542

Recent advances in the diagnosis and prognosis of amyotrophic lateral sclerosis

Goutman, S. A., Hardiman, O., Al-Chalabi, A., Chió, A., Savelieff, M. G., Kiernan, M. C., & Feldman, E. L. (2022) · The Lancet Neurology

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 493

ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)

Parkinson, N., Ince, P. G., Smith, M. O., Highley, R., Skibinski, G., Andersen, P. M., Morrison, K. E., Pall, H. S., Hardiman, O., Collinge, J., et al. (2006) · Neurology

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 395

Amyotrophic lateral sclerosis: moving towards a new classification system

Al-Chalabi, A., Hardiman, O., Kiernan, M. C., Chiò, A., Rix-Brooks, B., & van den Berg, L. H. (2016) · The Lancet Neurology

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 390

Detection of long repeat expansions from PCR-free whole-genome sequence data

Dolzhenko, E., van Vugt, J. J. F. A., Shaw, R. J., Bekritsky, M. A., van Blitterswijk, M., Narzisi, G., Ajay, S. S., Rajan, V., Lajoie, B. R., Johnson, N. H., et al. (2017) · Genome Research

Genomics and Rare DiseasesGenomics and Phylogenetic Studies

Cited by 388

Incidence and prevalence of ALS in Ireland, 1995–1997: A population-based study

Traynor, B. J., Codd, M. B., Corr, B., Forde, C., Frost, E., & Hardiman, O. (1999) · Neurology

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 292

Ethnic variation in the incidence of ALS: A systematic review

Cronin, S., Hardiman, O., & Traynor, B. J. (2007) · Neurology

Amyotrophic Lateral Sclerosis ResearchAmyloidosis: Diagnosis, Treatment, Outcomes

Cited by 255

Lifetime Risk and Heritability of Amyotrophic Lateral Sclerosis

Ryan, M., Heverin, M., McLaughlin, R. L., & Hardiman, O. (2019) · JAMA Neurology

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 244

The multistep hypothesis of ALS revisited: The role of genetic mutations

Chiò, A., Mazzini, L., D'Alfonso, S., Corrado, L., Canosa, A., Moglia, C., Manera, U., Bersano, E., Brunetti, M., Barberis, M., et al. (2018) · Neurology

Amyotrophic Lateral Sclerosis ResearchHereditary Neurological Disorders

Cited by 212

Epidemiology and clinical features of amyotrophic lateral sclerosis in Ireland between 1995 and 2004

O'Toole, O., Traynor, B. J., Brennan, P., Sheehan, C., Frost, E., Corr, B., & Hardiman, O. (2008) · Journal of Neurology, Neurosurgery & Psychiatry

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 197

Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms

Madill, M., McDonagh, K., Ma, J., Vajda, A., McLoughlin, P., O’Brien, T., Hardiman, O., & Shen, S. (2017) · Molecular Brain

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 134

The changing picture of amyotrophic lateral sclerosis: lessons from European registers

Hardiman, O., Al-Chalabi, A., Brayne, C., Beghi, E., van den Berg, L. H., Chio, A., Martin, S., Logroscino, G., & Rooney, J. (2017) · Journal of Neurology, Neurosurgery & Psychiatry

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 126

Palliative care in amyotrophic lateral sclerosis: a review of current international guidelines and initiatives

Bede, P., Oliver, D., Stodart, J., van den Berg, L., Simmons, Z., O Brannagain, D., Borasio, G. D., & Hardiman, O. (2011) · Journal of Neurology, Neurosurgery & Psychiatry

Palliative Care and End-of-Life IssuesAmyotrophic Lateral Sclerosis Research

Cited by 123

Physical activity and amyotrophic lateral sclerosis: A European population‐based case–control study

Pupillo, E., Messina, P., Giussani, G., Logroscino, G., Zoccolella, S., Chiò, A., Calvo, A., Corbo, M., Lunetta, C., Marin, B., et al. (2014) · Annals of Neurology

Amyotrophic Lateral Sclerosis ResearchPhysical Activity and Health

Cited by 105

Incidence of Syndromes Associated With Frontotemporal Lobar Degeneration in 9 European Countries

Logroscino, G., Piccininni, M., Graff, C., Hardiman, O., Ludolph, A. C., Moreno, F., Otto, M., Remes, A. M., Rowe, J. B., Seelaar, H., et al. (2023) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 91

Exerting control and adapting to loss in amyotrophic lateral sclerosis

Foley, G., Timonen, V., & Hardiman, O. (2014) · Social Science & Medicine

Amyotrophic Lateral Sclerosis ResearchPalliative Care and End-of-Life Issues

Cited by 76

Trauma and amyotrophic lateral sclerosis: a european population-based case-control study from the EURALS consortium

Pupillo, E., Poloni, M., Bianchi, E., Giussani, G., Logroscino, G., Zoccolella, S., Chiò, A., Calvo, A., Corbo, M., Lunetta, C., et al. (2018) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Amyotrophic Lateral Sclerosis ResearchSpinal Cord Injury Research

Cited by 38

Effect modification of the association between total cigarette smoking and ALS risk by intensity, duration and time-since-quitting: Euro-MOTOR

Peters, S., Visser, A. E., D'Ovidio, F., Vlaanderen, J., Portengen, L., Beghi, E., Chio, A., Logroscino, G., Hardiman, O., Pupillo, E., et al. (2020) · Journal of Neurology, Neurosurgery & Psychiatry

Amyotrophic Lateral Sclerosis ResearchSmoking Behavior and Cessation

Cited by 33

Experience of Services as a Key Outcome in Amyotrophic Lateral Sclerosis (ALS) Care: The Case for a Better Understanding of Patient Experiences

Foley, G., Timonen, V., & Hardiman, O. (2012) · American Journal of Hospice and Palliative Medicine®

Patient Satisfaction in HealthcareAmyotrophic Lateral Sclerosis Research

Cited by 21