Langefeld, Carl D.

Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

Genovese, G., Friedman, D. J., Ross, M. D., Lecordier, L., Uzureau, P., Freedman, B. I., Bowden, D. W., Langefeld, C. D., Oleksyk, T. K., Uscinski Knob, A. L., et al. (2010) · Science

Renal Diseases and GlomerulopathiesChronic Kidney Disease and Diabetes

Cited by 2,028

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

The International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley, J. B., Alarcón-Riquelme, M. E., Criswell, L. A., Jacob, C. O., Kimberly, R. P., Moser, K. L., Tsao, B. P., Vyse, T. J., & Langefeld, C. D. (2008) · Nature Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

Cited by 1,309

Integrated omics: tools, advances and future approaches

Misra, B. B., Langefeld, C., Olivier, M., & Cox, L. A. (2019) · Journal of Molecular Endocrinology

Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Cited by 686

Rare and low-frequency coding variants alter human adult height

Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., et al. (2017) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 610

A practical solution to pseudoreplication bias in single-cell studies

Zimmerman, K. D., Espeland, M. A., & Langefeld, C. D. (2021) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 356

Pseudoreplication bias in single-cell studies; a practical solution

Zimmerman, K. D., Espeland, M. A., & Langefeld, C. D. (2020) · Nature Communications

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 332

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

Schugar, R. C., Shih, D. M., Warrier, M., Helsley, R. N., Burrows, A., Ferguson, D., Brown, A. L., Gromovsky, A. D., Heine, M., Chatterjee, A., et al. (2017) · Cell Reports

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 291

Meta-analysis of Genome-wide Association Studies Identifies 1q22 as a Susceptibility Locus for Intracerebral Hemorrhage

Woo, D., Falcone, G. J., Devan, W. J., Brown, W. M., Biffi, A., Howard, T. D., Anderson, C. D., Brouwers, H. B., Valant, V., Battey, T. W. K., et al. (2014) · The American Journal of Human Genetics

Intracerebral and Subarachnoid Hemorrhage ResearchGenetic Associations and Epidemiology

Cited by 290

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

Adrianto, I., Wen, F., Templeton, A., Wiley, G., King, J. B., Lessard, C. J., Bates, J. S., Hu, Y., Kelly, J. A., Kaufman, K. M., et al. (2011) · Nature Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

Cited by 279

Complement genes contribute sex-biased vulnerability in diverse disorders

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., et al. (2020) · Nature

Systemic Lupus Erythematosus ResearchComplement system in diseases

Cited by 238

Visualizing Human Leukocyte Antigen Class II Risk Haplotypes in Human Systemic Lupus Erythematosus

Graham, R. R., Ortmann, W. A., Langefeld, C. D., Jawaheer, D., Selby, S. A., Rodine, P. R., Baechler, E. C., Rohlf, K. E., Shark, K. B., Espe, K. J., et al. (2002) · The American Journal of Human Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

Cited by 223

Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE

Graham, R. R., Ortmann, W., Rodine, P., Espe, K., Langefeld, C., Lange, E., Williams, A., Beck, S., Kyogoku, C., Moser, K., et al. (2007) · European Journal of Human Genetics

Systemic Lupus Erythematosus ResearchSystemic Sclerosis and Related Diseases

Cited by 174

Genetics of autoimmune diseases: Insights from population genetics

Ramos, P. S., Shedlock, A. M., & Langefeld, C. D. (2015) · Journal of Human Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 173

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

Rusu, V., Hoch, E., Mercader, J. M., Tenen, D. E., Gymrek, M., Hartigan, C. R., DeRan, M., von Grotthuss, M., Fontanillas, P., Spooner, A., et al. (2017) · Cell

Genetic Associations and EpidemiologyMetabolism, Diabetes, and Cancer

Cited by 152

Validation of probabilistic predictions

Miller, M. E., Langefeld, C. D., Tierney, W. M., Hui, S. L., & McDonald, C. J. (1993) · Medical Decision Making

Statistical Methods in EpidemiologyArtificial Intelligence in Healthcare

Cited by 129

Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis

Marini, S., Crawford, K., Morotti, A., Lee, M. J., Pezzini, A., Moomaw, C. J., Flaherty, M. L., Montaner, J., Roquer, J., Jimenez-Conde, J., et al. (2019) · JAMA Neurology

Intracerebral and Subarachnoid Hemorrhage ResearchGenetic Associations and Epidemiology

Cited by 68

Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans

Ng, M. C. Y., Saxena, R., Li, J., Palmer, N. D., Dimitrov, L., Xu, J., Rasmussen-Torvik, L. J., Zmuda, J. M., Siscovick, D. S., Patel, S. R., et al. (2013) · Diabetes

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 62

A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

Sung, Y. J., de las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., et al. (2019) · Human Molecular Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 43

Multi-omics profiling of primary human B cells activated via distinct stimuli

Aguiar, V. R. C., Franco, M. E., Abdel Aziz, N., Fernandez-Salinas, D., Chiñas, M., Colantuoni, M., Xiao, Q., Hackert, N., Liao, Y., Cervantes-Diaz, R., et al. (2026) · Nature Communications

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 0