Lautrup, Sofie

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

Fang, E. F., Hou, Y., Palikaras, K., Adriaanse, B. A., Kerr, J. S., Yang, B., Lautrup, S., Hasan-Olive, M. M., Caponio, D., Dan, X., et al. (2019) · Nature Neuroscience

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

Cited by 1,740

NAD+ in Brain Aging and Neurodegenerative Disorders

Lautrup, S., Sinclair, D. A., Mattson, M. P., & Fang, E. F. (2019) · Cell Metabolism

Sirtuins and Resveratrol in MedicineNuclear Receptors and Signaling

Cited by 790

NAD(+) in aging: molecular mechanisms and translational implications

Fang, E. F., Lautrup, S., Hou, Y., Demarest, T. G., Croteau, D. L., Mattson, M. P., & Bohr, V. A. (2017) · Trends in Molecular Medicine

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 501

NAD + supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Hou, Y., Lautrup, S., Cordonnier, S., Wang, Y., Croteau, D. L., Zavala, E., Zhang, Y., Moritoh, K., O’Connell, J. F., Baptiste, B. A., et al. (2018) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsSirtuins and Resveratrol in Medicine

Cited by 472

Mitophagy in neurodegeneration and aging

Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, M., Stevnsner, T., Nilsen, H., Bohr, V. A., & Fang, E. F. (2017) · Neurochemistry International

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 364

New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., et al. (2022) · Aging

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 319

Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease

Lautrup, S., Lou, G., Aman, Y., Nilsen, H., Tao, J., & Fang, E. F. (2019) · Neurochemistry International

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 105

DNA Damage-Induced Neurodegeneration in Accelerated Ageing and Alzheimer’s Disease

Wang, H., Lautrup, S., Caponio, D., Zhang, J., & Fang, E. (2021) · International Journal of Molecular Sciences

DNA Repair MechanismsAlzheimer's disease research and treatments

Cited by 55