Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease

A role for mitochondria in nlrp3 inflammasome activation

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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

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Autophagy and Aging

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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

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Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

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Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

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Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging

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Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

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Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

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Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

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The Alzheimer’s disease mitochondrial cascade hypothesis: progress and perspectives

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Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction

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Measuring In Vivo Mitophagy

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Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation

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NAD + Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

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Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

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A Cell Surface Receptor Complex for Fibrillar β-Amyloid Mediates Microglial Activation

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NAD ⁺ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

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Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

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Mitophagy in neurodegeneration and aging

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Protecting the mitochondrial powerhouse

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PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer’s disease

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Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

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Mitophagy and NAD + inhibit Alzheimer disease

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Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer’s Disease-Associated Presenilin 1 Mutation

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Mitochonic acid 5 activates the MAPK–ERK–yap signaling pathways to protect mouse microglial BV-2 cells against TNFα-induced apoptosis via increased Bnip3-related mitophagy

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Nicotinamide Riboside Ameliorates Hepatic Metaflammation by Modulating NLRP3 Inflammasome in a Rodent Model of Type 2 Diabetes

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In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice

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Turning up mitophagy in Alzheimer disease

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NAD+ in Brain Aging and Neurodegenerative Disorders

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Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer’s disease

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Autophagy in Alzheimer’s disease pathogenesis: Therapeutic potential and future perspectives

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NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway

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Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow

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NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome

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The biological pathways of Alzheimer disease: a review

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Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer’s Disease Pathogenesis

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Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration

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Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation

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Mitochondrial Dysfunction and Alzheimer’s Disease: Role of Microglia

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Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model

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Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia

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Improving Drug Delivery for Alzheimer’s Disease Through Nose-to-Brain Delivery Using Nanoemulsions, Nanostructured Lipid Carriers (NLC) and in situ Hydrogels

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Insulin Resistance at the Crossroad of Alzheimer Disease Pathology: A Review

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Mitochondrial dysfunctions, oxidative stress and neuroinflammation as therapeutic targets for neurodegenerative diseases: An update on current advances and impediments

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Brain Metabolic Alterations in Alzheimer’s Disease

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Microglia in Aging and Alzheimer’s Disease: A Comparative Species Review

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The role of innate immunity in Alzheimer's disease

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Re-emphasizing early Alzheimer’s disease pathology starting in select entorhinal neurons, with a special focus on mitophagy

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Interplay Between Mitochondrial Oxidative Disorders and Proteostasis in Alzheimer’s Disease

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Unraveling the role and mechanism of mitochondria in postoperative cognitive dysfunction: a narrative review

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Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer’s disease

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Dissecting the Crosstalk between Endothelial Mitochondrial Damage, Vascular Inflammation, and Neurodegeneration in Cerebral Amyloid Angiopathy and Alzheimer’s Disease

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Mitophagy and DNA damage signaling in human aging

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A multitude of signaling pathways associated with Alzheimer's disease and their roles in AD pathogenesis and therapy

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Mitophagy in depression: Pathophysiology and treatment targets

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Emerging perspectives on mitochondrial dysfunction and inflammation in Alzheimer’s disease

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The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

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Compromised autophagy and mitophagy in brain ageing and Alzheimer’s diseases.

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Impaired Mitophagy in Neurons and Glial Cells during Aging and Age-Related Disorders

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Microglia-Mediated Neurovascular Unit Dysfunction in Alzheimer’s Disease

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Mitophagy Modulation, a New Player in the Race against ALS

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Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing

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Cellular and molecular influencers of neuroinflammation in Alzheimer's disease: Recent concepts & roles

Ghosh, P., Singh, R. B., Ganeshpurkar, A., Pokle, A. V., Singh, R. B., Singh, S. K., & Kumar, A. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.105212 · Cited by 44 · see citing works

Neuroinflammation: Integrated Nervous Tissue Response through Intercellular Interactions at the “Whole System” Scale

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TREM2 ameliorates anesthesia and surgery-induced cognitive impairment by regulating mitophagy and NLRP3 inflammasome in aged C57/BL6 mice

Jiang, W., Liu, F., Li, H., Wang, K., Cao, X., Xu, X., Zhou, Y., Zou, J., Zhang, X., & Cui, X. (2022) · NeuroToxicology · doi:10.1016/j.neuro.2022.04.005 · Cited by 38 · see citing works

Nicotinamide Riboside and Metformin Ameliorate Mitophagy Defect in Induced Pluripotent Stem Cell-Derived Astrocytes With POLG Mutations

Chen, A., Kristiansen, C. K., Hong, Y., Kianian, A., Fang, E. F., Sullivan, G. J., Wang, J., Li, X., Bindoff, L. A., & Liang, K. X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.737304 · Cited by 36 · see citing works

Alzheimer’s Amyloid‐ β Accelerates Cell Senescence and Suppresses the SIRT1/NRF2 Pathway in Human Microglial Cells

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Prevention and Treatment Strategies for Alzheimer’s Disease: Focusing on Microglia and Astrocytes in Neuroinflammation

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Role of microglia autophagy and mitophagy in age-related neurodegenerative diseases

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Targeting Microglia in Alzheimer’s Disease: From Molecular Mechanisms to Potential Therapeutic Targets for Small Molecules

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Harnessing Mitophagy for Therapeutic Advances in Aging and Chronic Neurodegenerative Diseases

Ghosh, D., & Kumar, A. (2024) · Neuroglia · doi:10.3390/neuroglia5040026 · Cited by 36 · see citing works

Enhancing mitophagy as a therapeutic approach for neurodegenerative diseases

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Sirtuin 3 attenuates neuroinflammation-induced apoptosis in BV-2 microglia

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Brain insulin resistance linked Alzheimer’s and Parkinson’s disease pathology: An undying implication of epigenetic and autophagy modulation

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The immunometabolic reprogramming of microglia in Alzheimerʼs disease

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A Reactive Oxygen Species‐Responsive Targeted Nanoscavenger to Promote Mitophagy for the Treatment of Alzheimer's Disease

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Mitochondrial complex I abnormalities underlie neurodegeneration and cognitive decline in Alzheimer’s disease

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Neuron‐glia (mis)interactions in brain energy metabolism during aging

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Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy

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Inhibition of NLRP3 inflammasome ameliorates LPS-induced neuroinflammatory injury in mice via PINK1/Parkin pathway

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