Guchelaar, Henk-Jan

Genetics of rheumatoid arthritis contributes to biology and drug discovery

the RACI consortium, Okada, Y., the GARNET consortium, Wu, D., Trynka, G., Raj, T., Terao, C., Ikari, K., Kochi, Y., Ohmura, K., et al. (2014) · Nature

Rheumatoid Arthritis Research and TherapiesGenetic Associations and Epidemiology

Cited by 2,310

Clinical pharmacokinetics of tyrosine kinase inhibitors

van Erp, N. P., Gelderblom, H., & Guchelaar, H.-J. (2009) · Cancer Treatment Reviews

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 503

Making sense of big data in health research: towards an EU action plan

Auffray, C., Balling, R., Barroso, I., Bencze, L., Benson, M., Bergeron, J., Bernal-Delgado, E., Blomberg, N., Bock, C., Conesa, A., et al. (2016) · Genome Medicine

Electronic Health Records SystemsBig Data Technologies and Applications

Cited by 286

Effect of Concomitant CYP2D6 Inhibitor Use and Tamoxifen Adherence on Breast Cancer Recurrence in Early-Stage Breast Cancer

Dezentjé, V. O., van Blijderveen, N. J. C., Gelderblom, H., Putter, H., van Herk-Sukel, M. P. P., Casparie, M. K., Egberts, A. C. G., Nortier, J. W. R., & Guchelaar, H.-J. (2010) · Journal of Clinical Oncology

Pharmacogenetics and Drug MetabolismBreast Cancer Treatment Studies

Cited by 163

Mitotane has a strong and a durable inducing effect on CYP3A4 activity

van Erp, N. P., Guchelaar, H.-J., Ploeger, B. A., Romijn, J. A., Hartigh, J. D., & Gelderblom, H. (2011) · European Journal of Endocrinology

Pharmacogenetics and Drug MetabolismAdrenal Hormones and Disorders

Cited by 118

Lapatinib for Advanced or Metastatic Breast Cancer

Opdam, F. L., Guchelaar, H.-J., Beijnen, J. H., & Schellens, J. H. M. (2012) · The Oncologist

HER2/EGFR in Cancer ResearchCancer Treatment and Pharmacology

Cited by 113

Activation of Tumor-Promoting Type 2 Macrophages by EGFR-Targeting Antibody Cetuximab

Pander, J., Heusinkveld, M., van der Straaten, T., Jordanova, E. S., Baak-Pablo, R., Gelderblom, H., Morreau, H., van der Burg, S. H., Guchelaar, H.-J., & van Hall, T. (2011) · Clinical Cancer Research

Immune cells in cancerMonoclonal and Polyclonal Antibodies Research

Cited by 101

Concordance of predictive markers for EGFR inhibitors in primary tumors and metastases in colorectal cancer: A review

Baas, J. M., Krens, L. L., Guchelaar, H.-J., Morreau, H., & Gelderblom, H. (2011) · The Oncologist

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

Cited by 89

Direct access of drugs to the human brain after intranasal drug administration?

Merkus, P., Guchelaar, H.-J., Bosch, D. A., & Merkus, F. W. H. M. (2003) · Neurology

Advanced Drug Delivery SystemsBarrier Structure and Function Studies

Cited by 81

Erratum to: Making sense of big data in health research: towards an EU action plan

Auffray, C., Balling, R., Barroso, I., Bencze, L., Benson, M., Bergeron, J., Bernal-Delgado, E., Blomberg, N., Bock, C., Conesa, A., et al. (2016) · Genome Medicine

Research Data Management PracticesBig Data Technologies and Applications

Cited by 29