Lupas, Andrei N.

Predicting coiled coils from protein sequences.

Lupas, A., Van Dyke, M., & Stock, J. (1991) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 3,953

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

Zimmermann, L., Stephens, A., Nam, S.-Z., Rau, D., Kübler, J., Lozajic, M., Gabler, F., Söding, J., Lupas, A. N., & Alva, V. (2018) · Journal of Molecular Biology

Genomics and Phylogenetic StudiesProtein Structure and Dynamics

Cited by 2,522

Protein Sequence Analysis Using the MPI Bioinformatics Toolkit

Gabler, F., Nam, S., Till, S., Mirdita, M., Steinegger, M., Söding, J., Lupas, A. N., & Alva, V. (2020) · Current Protocols in Bioinformatics

Genomics and Phylogenetic StudiesProtein Structure and Dynamics

Cited by 831

The HAMP Domain Structure Implies Helix Rotation in Transmembrane Signaling

Hulko, M., Berndt, F., Gruber, M., Linder, J. U., Truffault, V., Schultz, A., Martin, J., Schultz, J. E., Lupas, A. N., & Coles, M. (2006) · Cell

Protein Structure and DynamicsBacterial Genetics and Biotechnology

Cited by 416

Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins

Hoiczyk, E., Roggenkamp, A., Reichenbecher, M., Lupas, A., & Heesemann, J. (2000) · The EMBO Journal

Yersinia bacterium, plague, ectoparasites researchBiochemical and Structural Characterization

Cited by 359

High‐accuracy protein structure prediction in CASP14

Pereira, J., Simpkin, A. J., Hartmann, M. D., Rigden, D. J., Keegan, R. M., & Lupas, A. N. (2021) · Proteins: Structure, Function, and Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 314

More than the sum of their parts: On the evolution of proteins from peptides

Söding, J., & Lupas, A. N. (2003) · BioEssays

Protein Structure and DynamicsOrigins and Evolution of Life

Cited by 252

Homology of SMP Domains to the TULIP Superfamily of Lipid-Binding Proteins Provides a Structural Basis for Lipid Exchange between ER and Mitochondria

Kopec, K. O., Alva, V., & Lupas, A. N. (2010) · Bioinformatics

Mitochondrial Function and PathologyLipid Membrane Structure and Behavior

Cited by 212

Thalidomide mimics uridine binding to an aromatic cage in cereblon

Hartmann, M. D., Boichenko, I., Coles, M., Zanini, F., Lupas, A. N., & Hernandez Alvarez, B. (2014) · Journal of Structural Biology

Protein Degradation and InhibitorsEnzyme Structure and Function

Cited by 83

Assessing the utility of CASP14 models for molecular replacement

Millán, C., Keegan, R. M., Pereira, J., Sammito, M. D., Simpkin, A. J., McCoy, A. J., Lupas, A. N., Hartmann, M. D., Rigden, D. J., & Read, R. J. (2021) · Proteins: Structure, Function, and Bioinformatics

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 62

Integrative Structural Biology in the Era of Accurate Structure Prediction

Masrati, G., Landau, M., Ben-Tal, N., Lupas, A., Kosloff, M., & Kosinski, J. (2021) · Journal of Molecular Biology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 53

Computational models in the service of X‐ray and cryo‐ electron microscopy structure determination

Kryshtafovych, A., Moult, J., Albrecht, R., Chang, G. A., Chao, K., Fraser, A., Greenfield, J., Hartmann, M. D., Herzberg, O., Josts, I., et al. (2021) · Proteins: Structure, Function, and Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 45

Histones predate the split between bacteria and archaea

Alva, V., & Lupas, A. N. (2019) · Bioinformatics

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 43

Coiled coils: new structures and new functions

Lupas, A. (1996) · Trends in Biochemical Sciences

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 34

Structural Dynamics of the Cereblon Ligand Binding Domain

Hartmann, M. D., Boichenko, I., Coles, M., Lupas, A. N., & Hernandez Alvarez, B. (2015) · PLOS ONE

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 31

New β-Propellers Are Continuously Amplified From Single Blades in all Major Lineages of the β-Propeller Superfamily

Pereira, J., & Lupas, A. N. (2022) · Frontiers in Molecular Biosciences

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 8

New β-propellers are continuously amplified from single blades in all major lineages of the β-propeller superfamily

Pereira, J., & Lupas, A. N. (2022) · Frontiers in Molecular Biosciences

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 8

DNA Wrapping by a Tetrameric Bacterial Histone

Hu, Y., Schwab, S., Qiu, K., Zhang, Y., Bär, K., Reichle, H., Panzera, A., Lupas, A. N., Hartmann, M. D., Dame, R. T., et al. (2025) · Nature Communications

Genomics and Chromatin DynamicsBacterial Genetics and Biotechnology

Cited by 7

A conserved motif suggests a common origin for a group of proteins involved in the cell division of Gram-positive bacteria

Martinez-Goikoetxea, M., & Lupas, A. N. (2022) · PLoS ONE

Bacterial Genetics and BiotechnologyBiochemical and Structural Characterization

Cited by 7

A computational model for lipid-anchored polysaccharide export by the outer-membrane protein GfcD

Fruet, C., Martinez-Goikoetxea, M., Merino, F., & Lupas, A. N. (2023) · Biophysical Journal

Lipid Membrane Structure and BehaviorBacterial Genetics and Biotechnology

Cited by 1

A computational model for lipid-anchored polysaccharide export by the outer membrane protein GfcD

Fruet, C., Martinez-Goikoetxea, M., Merino, F., & Lupas, A. N. (2024) · Biophysical Journal

Lipid Membrane Structure and BehaviorBacterial Genetics and Biotechnology

Cited by 1