Darbar, Dawood

The mutational constraint spectrum quantified from variation in 141,456 humans

Karczewski, K. J., Francioli, L. C., Tiao, G., Cummings, B. B., Alföldi, J., Wang, Q., Collins, R. L., Laricchia, K. M., Ganna, A., Birnbaum, D. P., et al. (2020) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 9,434

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Taliun, D., Harris, D. N., Kessler, M. D., Carlson, J., Szpiech, Z. A., Torres, R., Taliun, S. A. G., Corvelo, A., Gogarten, S. M., Kang, H. M., et al. (2021) · Nature

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 2,213

A genomic mutational constraint map using variation in 76,156 human genomes

Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 1,727

A structural variation reference for medical and population genetics

Collins, R. L., Brand, H., Karczewski, K. J., Zhao, X., Alföldi, J., Francioli, L. C., Khera, A. V., Lowther, C., Gauthier, L. D., Wang, H., et al. (2020) · Nature

Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases

Cited by 1,037

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Bick, A. G., Weinstock, J. S., Nandakumar, S. K., Fulco, C. P., Bao, E. L., Zekavat, S. M., Szeto, M. D., Liao, X., Leventhal, M. J., Nasser, J., et al. (2020) · Nature

Acute Myeloid Leukemia ResearchGenetic Associations and Epidemiology

Cited by 733

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

Ellinor, P. T., Lunetta, K. L., Albert, C. M., Glazer, N. L., Ritchie, M. D., Smith, A. V., Arking, D. E., Müller-Nurasyid, M., Krijthe, B. P., Lubitz, S. A., et al. (2012) · Nature Genetics

Atrial Fibrillation Management and OutcomesGenetic Associations and Epidemiology

Cited by 601

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

Gudbjartsson, D. F., Holm, H., Gretarsdottir, S., Thorleifsson, G., Walters, G. B., Thorgeirsson, G., Gulcher, J., Mathiesen, E. B., Njølstad, I., Nyrnes, A., et al. (2009) · Nature Genetics

Atrial Fibrillation Management and OutcomesGenetic Associations and Epidemiology

Cited by 489

Common variants in KCNN3 are associated with lone atrial fibrillation

Ellinor, P. T., Lunetta, K. L., Glazer, N. L., Pfeufer, A., Alonso, A., Chung, M. K., Sinner, M. F., de Bakker, P. I. W., Mueller, M., Lubitz, S. A., et al. (2010) · Nature Genetics

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 485

Metabolic Syndrome and Risk of Development of Atrial Fibrillation: The Niigata Preventive Medicine Study

Watanabe, H., Tanabe, N., Watanabe, T., Darbar, D., Roden, D. M., Sasaki, S., & Aizawa, Y. (2008) · Circulation

Atrial Fibrillation Management and OutcomesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 427

Cardiac Sodium Channel ( SCN5A ) Variants Associated with Atrial Fibrillation

Darbar, D., Kannankeril, P. J., Donahue, B. S., Kucera, G., Stubblefield, T., Haines, J. L., George, A. L., & Roden, D. M. (2008) · Circulation

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 334

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

Sinner, M. F., Tucker, N. R., Lunetta, K. L., Ozaki, K., Smith, J. G., Trompet, S., Bis, J. C., Lin, H., Chung, M. K., Nielsen, J. B., et al. (2014) · Circulation

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 205

Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes

Yoneda, Z. T., Anderson, K. C., Quintana, J. A., O’Neill, M. J., Sims, R. A., Glazer, A. M., Shaffer, C. M., Crawford, D. M., Stricker, T., Ye, F., et al. (2021) · JAMA Cardiology

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 192

Relation of the Severity of Obstructive Sleep Apnea in Response to Anti-Arrhythmic Drugs in Patients With Atrial Fibrillation or Atrial Flutter

Monahan, K., Brewster, J., Wang, L., Parvez, B., Goyal, S., Roden, D. M., & Darbar, D. (2012) · The American Journal of Cardiology

Obstructive Sleep Apnea ResearchAtrial Fibrillation Management and Outcomes

Cited by 170

Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation

Ritchie, M. D., Rowan, S., Kucera, G., Stubblefield, T., Blair, M., Carter, S., Roden, D. M., & Darbar, D. (2012) · Journal of the American College of Cardiology

Cardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Cited by 91

Exaggerated QT prolongation after cardioversion of atrial fibrillation

Choy, A. M. J., Darbar, D., Dell’Orto, S., & Roden, D. M. (1999) · Journal of the American College of Cardiology

Atrial Fibrillation Management and OutcomesCardiac electrophysiology and arrhythmias

Cited by 89

Relation of morbid obesity and female gender to risk of procedural complications in patients undergoing atrial fibrillation ablation

Shoemaker, M. B., Muhammad, R., Farrell, M., Parvez, B., White, B. W., Streur, M., Stubblefield, T., Rytlewski, J., Parvathaneni, S., Nagarakanti, R., et al. (2013) · The American Journal of Cardiology

Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and Treatments

Cited by 63

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J.-W., et al. (2022) · Nature Communications

Cardiac electrophysiology and arrhythmiasGenetic Associations and Epidemiology

Cited by 49

Human induced pluripotent stem cell-derived atrial cardiomyocytes carrying an SCN5A mutation identify nitric oxide signaling as a mediator of atrial fibrillation

Hong, L., Zhang, M., Ly, O. T., Chen, H., Sridhar, A., Lambers, E., Chalazan, B., Youn, S.-W., Maienschein-Cline, M., Feferman, L., et al. (2021) · Stem Cell Reports

Cardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research

Cited by 44

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

Cade, B. E., Lee, J., Sofer, T., Wang, H., Zhang, M., Chen, H., Gharib, S. A., Gottlieb, D. J., Guo, X., Lane, J. M., et al. (2021) · Genome Medicine

Obstructive Sleep Apnea ResearchGenetic Associations and Epidemiology

Cited by 33