Simons, Benjamin D.

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

Snippert, H. J., van der Flier, L. G., Sato, T., van Es, J. H., van den Born, M., Kroon-Veenboer, C., Barker, N., Klein, A. M., van Rheenen, J., Simons, B. D., et al. (2010) · Cell

Developmental Biology and Gene RegulationCancer Cells and Metastasis

Cited by 1,951

A single-cell molecular map of mouse gastrulation and early organogenesis

Pijuan-Sala, B., Griffiths, J. A., Guibentif, C., Hiscock, T. W., Jawaid, W., Calero-Nieto, F. J., Mulas, C., Ibarra-Soria, X., Tyser, R. C. V., Ho, D. L. L., et al. (2019) · Nature

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 1,033

A single type of progenitor cell maintains normal epidermis

Clayton, E., Doupé, D. P., Klein, A. M., Winton, D. J., Simons, B. D., & Jones, P. H. (2007) · Nature

Hair Growth and DisordersSkin and Cellular Biology Research

Cited by 853

Strategies for Homeostatic Stem Cell Self-Renewal in Adult Tissues

Simons, B. D., & Clevers, H. (2011) · Cell

Developmental Biology and Gene RegulationHematopoietic Stem Cell Transplantation

Cited by 489

Extensive Proliferation of a Subset of Differentiated, yet Plastic, Medial Vascular Smooth Muscle Cells Contributes to Neointimal Formation in Mouse Injury and Atherosclerosis Models

Chappell, J., Harman, J. L., Narasimhan, V. M., Yu, H., Foote, K., Simons, B. D., Bennett, M. R., & Jørgensen, H. F. (2016) · Circulation Research

Atherosclerosis and Cardiovascular DiseasesCardiovascular, Neuropeptides, and Oxidative Stress Research

Cited by 437

2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

Otani, T., Marchetto, M. C., Gage, F. H., Simons, B. D., & Livesey, F. J. (2016) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 353

Multipotent and unipotent progenitors contribute to prostate postnatal development

Ousset, M., Van Keymeulen, A., Bouvencourt, G., Sharma, N., Achouri, Y., Simons, B. D., & Blanpain, C. (2012) · Nature Cell Biology

Prostate Cancer Treatment and ResearchDevelopmental Biology and Gene Regulation

Cited by 221

Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy

Basak, O., Krieger, T. G., Muraro, M. J., Wiebrands, K., Stange, D. E., Frias-Aldeguer, J., Rivron, N. C., van de Wetering, M., van Es, J. H., van Oudenaarden, A., et al. (2018) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 186

Identification of a regeneration-organizing cell in the Xenopus tail

Aztekin, C., Hiscock, T. W., Marioni, J. C., Gurdon, J. B., Simons, B. D., & Jullien, J. (2019) · Science

Planarian Biology and ElectrostimulationDevelopmental Biology and Gene Regulation

Cited by 142

Early stem cell aging in the mature brain

Ibrayeva, A., Bay, M., Pu, E., Jörg, D. J., Peng, L., Jun, H., Zhang, N., Aaron, D., Lin, C., Resler, G., et al. (2021) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 137

Tracing oncogene-driven remodelling of the intestinal stem cell niche

Yum, M. K., Han, S., Fink, J., Wu, S.-H. S., Dabrowska, C., Trendafilova, T., Mustata, R., Chatzeli, L., Azzarelli, R., Pshenichnaya, I., et al. (2021) · Nature

Cancer Cells and MetastasisWnt/β-catenin signaling in development and cancer

Cited by 114

Long-term expansion, genomic stability and in vivo safety of adult human pancreas organoids

Georgakopoulos, N., Prior, N., Angres, B., Mastrogiovanni, G., Cagan, A., Harrison, D., Hindley, C. J., Arnes-Benito, R., Liau, S.-S., Curd, A., et al. (2020) · BMC Developmental Biology

Pancreatic function and diabetesPancreatic and Hepatic Oncology Research

Cited by 112

Muscle Stem Cells Exhibit Distinct Clonal Dynamics in Response to Tissue Repair and Homeostatic Aging

Tierney, M. T., Stec, M. J., Rulands, S., Simons, B. D., & Sacco, A. (2018) · Cell Stem Cell

Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation

Cited by 92