Hajjar, Roger J.

Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer

Sakata, S., Lebeche, D., Sakata, Y., Sakata, N., Chemaly, E. R., Liang, L. F., Padmanabhan, P., Konishi, N., Takaki, M., del Monte, F., et al. (2006) · Molecular Therapy

Cardiovascular Function and Risk FactorsCardiac electrophysiology and arrhythmias

Cited by 57

Anellovirus Structure Reveals a Mechanism for Immune Evasion

Liou, S.-H., Cohen, N., Zhang, Y., Acharekar, N. M., Rodgers, H., Islam, S., Zeheb, L., Pitts, J., Arze, C., Swaminathan, H., et al. (2022) · Nature Communications

Viral gastroenteritis research and epidemiologyEnzyme Structure and Function

Cited by 52

Cardiac adenylyl cyclase overexpression precipitates and aggravates age-related myocardial dysfunction

Mougenot, N., Mika, D., Czibik, G., Marcos, E., Abid, S., Houssaini, A., Vallin, B., Guellich, A., Mehel, H., Sawaki, D., et al. (2019) · Cardiovascular Research

Phosphodiesterase function and regulationCardiac electrophysiology and arrhythmias

Cited by 40

Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs

Chen, G., Li, S., Karakikes, I., Ren, L., Zi-Ying Chow, M., Chopra, A., Keung, W., Yan, B., Chan, C. W. Y., Costa, K. D., et al. (2015) · Circulation: Arrhythmia and Electrophysiology

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 38

Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts

Sakata, S., Lebeche, D., Sakata, N., Sakata, Y., Chemaly, E. R., Liang, L. F., Takewa, Y., Jeong, D., Park, W. J., Kawase, Y., et al. (2007) · American Journal of Physiology-Heart and Circulatory Physiology

Cardiac electrophysiology and arrhythmiasCardiomyopathy and Myosin Studies

Cited by 36

Introducing Genes to the Heart: All About Delivery

Hajjar, R. J., & Ishikawa, K. (2017) · Circulation Research

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 36

Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure

Fargnoli, A. S., Katz, M. G., Yarnall, C., Isidro, A., Petrov, M., Steuerwald, N., Ghosh, S., Richardville, K. C., Hillesheim, R., Williams, R. D., et al. (2013) · The Annals of Thoracic Surgery

Virus-based gene therapy researchMechanical Circulatory Support Devices

Cited by 27

Effect of bortezomib on the efficacy of AAV9. SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure

Chaanine, A. H., Nonnenmacher, M., Kohlbrenner, E., Jin, D., Kovacic, J. C., Akar, F. G., Hajjar, R. J., & Weber, T. (2014) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 25

Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues

Wong, A. O.-T., Gurung, B., Wong, W. S., Mak, S. Y., Tse, W. W., Li, C. M., Lieu, D. K., Costa, K. D., Li, R. A., & Hajjar, R. J. (2021) · Journal of Molecular and Cellular Cardiology

Cardiac electrophysiology and arrhythmiasPluripotent Stem Cells Research

Cited by 16

Reversal of contractile defects by mediating calcium homeostasis in human mini-heart models of heart failure with preserved ejection fraction (HFpEF) leads to first-in-human gene therapy clinical trial

Costa, K. D., Wong, A. O. T., Mak, S. Y., Roberts, E. G., Keung, W., Correia, C., Walentinsson, A., Christoffersson, J., Cheung, A., Lieu, D. K., et al. (2024) · bioRxiv

Cardiac electrophysiology and arrhythmiasCardiovascular Function and Risk Factors

Cited by 5