Distler, Jörg H. W.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,897

Update of EULAR recommendations for the treatment of systemic sclerosis

Kowal-Bielecka, O., Fransen, J., Avouac, J., Becker, M., Kulak, A., Allanore, Y., Distler, O., Clements, P., Cutolo, M., Czirjak, L., et al. (2017) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesPulmonary Hypertension Research and Treatments

Cited by 1,104

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

Akhmetshina, A., Palumbo, K., Dees, C., Bergmann, C., Venalis, P., Zerr, P., Horn, A., Kireva, T., Beyer, C., Zwerina, J., et al. (2012) · Nature Communications

TGF-β signaling in diseasesWnt/β-catenin signaling in development and cancer

Cited by 843

Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis

Distler, J. H. W., Jüngel, A., Huber, L. C., Schulze‐Horsel, U., Zwerina, J., Gay, R. E., Michel, B. A., Hauser, T., Schett, G., Gay, S., et al. (2007) · Arthritis & Rheumatism

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 383

Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis

Chakraborty, D., Šumová, B., Mallano, T., Chen, C.-W., Distler, A., Bergmann, C., Ludolph, I., Horch, R. E., Gelse, K., Ramming, A., et al. (2017) · Nature Communications

Systemic Sclerosis and Related DiseasesCytokine Signaling Pathways and Interactions

Cited by 356

Platelet-derived serotonin links vascular disease and tissue fibrosis

Dees, C., Akhmetshina, A., Zerr, P., Reich, N., Palumbo, K., Horn, A., Jüngel, A., Beyer, C., Krönke, G., Zwerina, J., et al. (2011) · Journal of Experimental Medicine

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 266

β-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis

Beyer, C., Schramm, A., Akhmetshina, A., Dees, C., Kireva, T., Gelse, K., Sonnylal, S., de Crombrugghe, B., Taketo, M. M., Distler, O., et al. (2012) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 203

Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis

Huang, J., Beyer, C., Palumbo-Zerr, K., Zhang, Y., Ramming, A., Distler, A., Gelse, K., Distler, O., Schett, G., Wollin, L., et al. (2016) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 196

Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis

Akhmetshina, A., Dees, C., Pileckyte, M., Maurer, B., Axmann, R., Jüngel, A., Zwerina, J., Gay, S., Schett, G., Distler, O., et al. (2008) · The FASEB Journal

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 187

PU.1 controls fibroblast polarization and tissue fibrosis

Wohlfahrt, T., Rauber, S., Uebe, S., Luber, M., Soare, A., Ekici, A., Weber, S., Matei, A.-E., Chen, C.-W., Maier, C., et al. (2019) · Nature

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 187

Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss

Lin, N.-Y., Chen, C.-W., Kagwiria, R., Liang, R., Beyer, C., Distler, A., Luther, J., Engelke, K., Schett, G., & Distler, J. H. (2016) · Annals of the Rheumatic Diseases

Bone Metabolism and DiseasesAutophagy in Disease and Therapy

Cited by 123

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis

Reich, N., Maurer, B., Akhmetshina, A., Venalis, P., Dees, C., Zerr, P., Palumbo, K., Zwerina, J., Nevskaya, T., Gay, S., et al. (2010) · Arthritis & Rheumatism

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 112

Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis

Krämer, M., Dees, C., Huang, J., Schlottmann, I., Palumbo-Zerr, K., Zerr, P., Gelse, K., Beyer, C., Distler, A., Marquez, V. E., et al. (2013) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 109

The Fra-2 transgenic mouse model of systemic sclerosis

Maurer, B., Distler, J. H. W., & Distler, O. (2013) · Vascular Pharmacology

Systemic Sclerosis and Related DiseasesPulmonary Hypertension Research and Treatments

Cited by 71

Autophagy: A key pathway of TNF-induced inflammatory bone loss

Lin, N.-Y., Stefanica, A., & Distler, J. H. W. (2013) · Autophagy

Bone Metabolism and DiseasesAutophagy in Disease and Therapy

Cited by 64

Synovial immunopathology in haemochromatosis arthropathy

Heiland, G. R., Aigner, E., Dallos, T., Sahinbegovic, E., Krenn, V., Thaler, C., Weiss, G., Distler, J. H., Datz, C., Schett, G., et al. (2010) · Annals of the Rheumatic Diseases

Iron Metabolism and DisordersOsteoarthritis Treatment and Mechanisms

Cited by 64

Inhibition of casein kinase II reduces TGFβ induced fibroblast activation and ameliorates experimental fibrosis

Zhang, Y., Dees, C., Beyer, C., Lin, N.-Y., Distler, A., Zerr, P., Palumbo, K., Susok, L., Kreuter, A., Distler, O., et al. (2015) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 64

The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis

Bergmann, C., Brandt, A., Merlevede, B., Hallenberger, L., Dees, C., Wohlfahrt, T., Pötter, S., Zhang, Y., Chen, C.-W., Mallano, T., et al. (2018) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 62

Nucleofection: a new, highly efficient transfection method for primary human keratinocytes*

Distler, J. H. W., Jüngel, A., Kurowska‐Stolarska, M., Michel, B. A., Gay, R. E., Gay, S., & Distler, O. (2005) · Experimental Dermatology

RNA Interference and Gene DeliveryMicrobial Inactivation Methods

Cited by 53

Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis

Dosoki, H., Stegemann, A., Taha, M., Schnittler, H., Luger, T. A., Schröder, K., Distler, J. H. W., Kerkhoff, C., & Böhm, M. (2017) · Experimental Dermatology

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

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