Taga, Mariko

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

Olah, M., Menon, V., Habib, N., Taga, M. F., Ma, Y., Yung, C. J., Cimpean, M., Khairallah, A., Coronas-Samano, G., Sankowski, R., et al. (2020) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 722

A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease

Mostafavi, S., Gaiteri, C., Sullivan, S. E., White, C. C., Tasaki, S., Xu, J., Taga, M., Klein, H.-U., Patrick, E., Komashko, V., et al. (2018) · Nature Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 509

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Sieberts, S. K., Perumal, T. M., Carrasquillo, M. M., Allen, M., Reddy, J. S., Hoffman, G. E., Dang, K. K., Calley, J., Ebert, P. J., Eddy, J., et al. (2020) · Scientific Data

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 318

Microglial immunophenotype in dementia with Alzheimer’s pathology

CFAS, M., Minett, T., Classey, J., Matthews, F. E., Fahrenhold, M., Taga, M., Brayne, C., Ince, P. G., Nicoll, J. A. R., & Boche, D. (2016) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 219

Cellular communities reveal trajectories of brain ageing and Alzheimer’s disease

Green, G. S., Fujita, M., Yang, H.-S., Taga, M., Cain, A., McCabe, C., Comandante-Lou, N., White, C. C., Schmidtner, A. K., Zeng, L., et al. (2024) · Nature

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 204

Multi-cellular communities are perturbed in the aging human brain and Alzheimer’s disease

Cain, A., Taga, M., McCabe, C., Green, G., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2020) · Nature Neuroscience

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 143

Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease

Cain, A., Taga, M., McCabe, C., Green, G. S., Hekselman, I., White, C. C., Lee, D. I., Gaur, P., Rozenblatt-Rosen, O., Zhang, F., et al. (2023) · Nature Neuroscience

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 142

BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology

Taga, M., Petyuk, V. A., White, C., Marsh, G., Ma, Y., Klein, H.-U., Connor, S. M., Kroshilina, A., Yung, C. J., Khairallah, A., et al. (2020) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 81

INPP5D regulates inflammasome activation in human microglia

Chou, V., Pearse, R. V., Aylward, A. J., Ashour, N., Taga, M., Terzioglu, G., Fujita, M., Fancher, S. B., Sigalov, A., Benoit, C. R., et al. (2023) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 79

Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease

Green, G. S., Fujita, M., Yang, H.-S., Taga, M., McCabe, C., Cain, A., White, C. C., Schmidtner, A. K., Zeng, L., Wang, Y., et al. (2023) · Alzheimer s & Dementia

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 51

Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer’s disease

Green, G. S., Yang, H., Fujita, M., Taga, M., Regev, A., Menon, V., Bennett, D. A. A., Habib, N., & De Jager, P. L. (2023) · Alzheimer's & Dementia

Single-cell and spatial transcriptomicsAlzheimer's disease research and treatments

Cited by 51

Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A β and TAU proteostasis

Sullivan, S. E., Liao, M., Smith, R. V., White, C., Lagomarsino, V. N., Xu, J., Taga, M., Bennett, D. A., De Jager, P. L., & Young-Pearse, T. L. (2019) · Human Molecular Genetics

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 44

A cortical immune network map identifies a subset of human microglia involved in Tau pathology

Patrick, E., Olah, M., Taga, M., Klein, H.-U., Xu, J., White, C. C., Felsky, D., Gaiteri, C., Chibnik, L. B., Mostafavi, S., et al. (2017) · Translational Psychiatry

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 39

A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

Patrick, E., Olah, M., Taga, M., Klein, H.-U., Xu, J., White, C. C., Felsky, D., Agrawal, S., Gaiteri, C., Chibnik, L. B., et al. (2021) · Translational Psychiatry

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 31