Gius, David

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress

Tao, R., Coleman, M. C., Pennington, J. D., Ozden, O., Park, S.-H., Jiang, H., Kim, H.-S., Flynn, C. R., Hill, S., Hayes McDonald, W., et al. (2010) · Molecular Cell

Sirtuins and Resveratrol in MedicineRedox biology and oxidative stress

Cited by 899

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

Kim, H.-S., Patel, K., Muldoon-Jacobs, K., Bisht, K. S., Aykin-Burns, N., Pennington, J. D., van der Meer, R., Nguyen, P., Savage, J., Owens, K. M., et al. (2010) · Cancer Cell

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 785

Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: a unifying concept in stress response biology

Spitz, D. R., Azzam, E. I., Jian Li, J., & Gius, D. (2004) · Cancer and Metastasis Reviews

Effects of Radiation ExposureRedox biology and oxidative stress

Cited by 710

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

Zhang, S., Weinberg, S., DeBerge, M., Gainullina, A., Schipma, M., Kinchen, J. M., Ben-Sahra, I., Gius, D. R., Yvan-Charvet, L., Chandel, N. S., et al. (2019) · Cell Metabolism

Phagocytosis and Immune RegulationSirtuins and Resveratrol in Medicine

Cited by 485

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

Kendrick, A. A., Choudhury, M., Rahman, S. M., McCurdy, C. E., Friederich, M., Van Hove, J. L. K., Watson, P. A., Birdsey, N., Bao, J., Gius, D., et al. (2011) · Biochemical Journal

Sirtuins and Resveratrol in MedicineLiver Disease Diagnosis and Treatment

Cited by 382

Regulation of MnSOD Enzymatic Activity by Sirt3 Connects the Mitochondrial Acetylome Signaling Networks to Aging and Carcinogenesis

Tao, R., Vassilopoulos, A., Parisiadou, L., Yan, Y., & Gius, D. (2014) · Antioxidants & Redox Signaling

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 194

SIRT3 Deacetylates ATP Synthase F 1 Complex Proteins in Response to Nutrient- and Exercise-Induced Stress

Vassilopoulos, A., Pennington, J. D., Andresson, T., Rees, D. M., Bosley, A. D., Fearnley, I. M., Ham, A., Flynn, C. R., Hill, S., Rose, K. L., et al. (2014) · Antioxidants & Redox Signaling

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 173

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

Bao, J., Scott, I., Lu, Z., Pang, L., Dimond, C. C., Gius, D., & Sack, M. N. (2010) · Free Radical Biology and Medicine

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 157

SIRT3 is crucial for maintaining skeletal muscle insulin action and protects against severe insulin resistance in high-fat-fed mice

Lantier, L., Williams, A. S., Williams, I. M., Yang, K. K., Bracy, D. P., Goelzer, M., James, F. D., Gius, D., & Wasserman, D. H. (2015) · Diabetes

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 151

Dietary restriction: standing up for sirtuins

Baur, J. A., Chen, D., Chini, E. N., Chua, K., Cohen, H. Y., Cabo, R. D., Deng, C., Dimmeler, S., Gius, D., Guarente, L. P., et al. (2010) · Science

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 76

Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3—modulated adhesion and invasion

Kassis, J. N., Virador, V. M., Guancial, E. A., Kimm, D., Ho, A. S., Mishra, M., Chuang, E. Y., Cook, J., Gius, D., & Kohn, E. C. (2009) · The Journal of Pathology

Connective Tissue Growth Factor ResearchHeat shock proteins research

Cited by 34