Cox, Thomas R.

Pre-metastatic niches: organ-specific homes for metastases

Peinado, H., Zhang, H., Matei, I. R., Costa-Silva, B., Hoshino, A., Rodrigues, G., Psaila, B., Kaplan, R. N., Bromberg, J. F., Kang, Y., et al. (2017) · Nature Reviews Cancer

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 1,889

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

Cox, T. R., & Erler, J. T. (2011) · Disease Models & Mechanisms

Cellular Mechanics and InteractionsTGF-β signaling in diseases

Cited by 1,569

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

Erler, J. T., Bennewith, K. L., Cox, T. R., Lang, G., Bird, D., Koong, A., Le, Q.-T., & Giaccia, A. J. (2009) · Cancer Cell

Cancer Cells and MetastasisImmune cells in cancer

Cited by 1,231

LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis

Cox, T. R., Bird, D., Baker, A.-M., Barker, H. E., Ho, M. W.-Y., Lang, G., & Erler, J. T. (2013) · Cancer Research

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 571

RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

Cox, T. R., Rumney, R. M. H., Schoof, E. M., Perryman, L., Høye, A. M., Agrawal, A., Bird, D., Latif, N. A., Forrest, H., Evans, H. R., et al. (2015) · Nature

Bone health and treatmentsCancer Cells and Metastasis

Cited by 482

Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer

Cazet, A. S., Hui, M. N., Elsworth, B. L., Wu, S. Z., Roden, D., Chan, C.-L., Skhinas, J. N., Collot, R., Yang, J., Harvey, K., et al. (2018) · Nature Communications

Hedgehog Signaling Pathway StudiesCancer Cells and Metastasis

Cited by 437

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Vennin, C., Mélénec, P., Rouet, R., Nobis, M., Cazet, A. S., Murphy, K. J., Herrmann, D., Reed, D. A., Lucas, M. C., Warren, S. C., et al. (2019) · Nature Communications

Pancreatic and Hepatic Oncology ResearchCancer Cells and Metastasis

Cited by 268

Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan

Elgundi, Z., Papanicolaou, M., Major, G., Cox, T. R., Melrose, J., Whitelock, J. M., & Farrugia, B. L. (2020) · Frontiers in Oncology

Proteoglycans and glycosaminoglycans researchProtease and Inhibitor Mechanisms

Cited by 176

Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis

Madsen, C. D., Pedersen, J. T., Venning, F. A., Singh, L. B., Moeendarbary, E., Charras, G., Cox, T. R., Sahai, E., & Erler, J. T. (2015) · The EMBO Reports

Cancer Cells and MetastasisCancer, Hypoxia, and Metabolism

Cited by 157

Tissue section AFM: In situ ultrastructural imaging of native biomolecules

Graham, H. K., Hodson, N. W., Hoyland, J. A., Millward-Sadler, S. J., Garrod, D., Scothern, A., Griffiths, C. E. M., Watson, R. E. B., Cox, T. R., Erler, J. T., et al. (2010) · Matrix Biology

Force Microscopy Techniques and ApplicationsCellular Mechanics and Interactions

Cited by 116

Proteomic Profiling of Human Prostate Cancer-associated Fibroblasts (CAF) Reveals LOXL2-dependent Regulation of the Tumor Microenvironment

Nguyen, E. V., Pereira, B. A., Lawrence, M. G., Ma, X., Rebello, R. J., Chan, H., Niranjan, B., Wu, Y., Ellem, S., Guan, X., et al. (2019) · Molecular & Cellular Proteomics

Prostate Cancer Treatment and ResearchProtease and Inhibitor Mechanisms

Cited by 107

Bovine and human endometrium-derived hydrogels support organoid culture from healthy and cancerous tissues

Jamaluddin, M. F. B., Ghosh, A., Ingle, A., Mohammed, R., Ali, A., Bahrami, M., Kaiko, G., Gibb, Z., Filipe, E. C., Cox, T. R., et al. (2022) · Proceedings of the National Academy of Sciences

Tissue Engineering and Regenerative MedicineHydrogels: synthesis, properties, applications

Cited by 84