Eliasson, Lena

A pancreatic islet-specific microRNA regulates insulin secretion

Poy, M. N., Eliasson, L., Krutzfeldt, J., Kuwajima, S., Ma, X., MacDonald, P. E., Pfeffer, S., Tuschl, T., Rajewsky, N., Rorsman, P., et al. (2004) · Nature

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 2,102

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion

Dayeh, T., Volkov, P., Salö, S., Hall, E., Nilsson, E., Olsson, A. H., Kirkpatrick, C. L., Wollheim, C. B., Eliasson, L., Rönn, T., et al. (2014) · PLoS Genetics

Epigenetics and DNA MethylationPancreatic function and diabetes

Cited by 523

Protein kinase A‐dependent and ‐independent stimulation of exocytosis by cAMP in mouse pancreatic B‐cells

Renström, E., Eliasson, L., & Rorsman, P. (1997) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 299

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

Olofsson, C. S., Göpel, S. O., Barg, S., Galvanovskis, J., Ma, X., Salehi, A., Rorsman, P., & Eliasson, L. (2002) · Pflügers Archiv

Pancreatic function and diabetesCellular transport and secretion

Cited by 290

MicroRNA-7a regulates pancreatic β cell function

Latreille, M., Hausser, J., Stützer, I., Zhang, Q., Hastoy, B., Gargani, S., Kerr-Conte, J., Pattou, F., Zavolan, M., Esguerra, J. L. S., et al. (2014) · Journal of Clinical Investigation

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 281

Exocytosis elicited by action potentials and voltage‐clamp calcium currents in individual mouse pancreatic B‐cells.

Ammälä, C., Eliasson, L., Bokvist, K., Larsson, O., Ashcroft, F. M., & Rorsman, P. (1993) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 270

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

De Marinis, Y. Z., Salehi, A., Ward, C. E., Zhang, Q., Abdulkader, F., Bengtsson, M., Braha, O., Braun, M., Ramracheya, R., Amisten, S., et al. (2010) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 257

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells

Eliasson, L., Ma, X., Renström, E., Barg, S., Berggren, P.-O., Galvanovskis, J., Gromada, J., Jing, X., Lundquist, I., Salehi, A., et al. (2003) · The Journal of General Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 257

Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells

Barg, S., Ma, X., Eliasson, L., Galvanovskis, J., Göpel, S. O., Obermüller, S., Platzer, J., Renström, E., Trus, M., Atlas, D., et al. (2001) · Biophysical Journal

Pancreatic function and diabetesCellular transport and secretion

Cited by 255

Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

Hall, E., Volkov, P., Dayeh, T., Esguerra, J. L. S., Salö, S., Eliasson, L., Rönn, T., Bacos, K., & Ling, C. (2014) · Genome Biology

Epigenetics and DNA MethylationPancreatic function and diabetes

Cited by 249

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

Rosengren, A. H., Braun, M., Mahdi, T., Andersson, S. A., Travers, M. E., Shigeto, M., Zhang, E., Almgren, P., Ladenvall, C., Axelsson, A. S., et al. (2012) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 237

A Subset of 50 Secretory Granules in Close Contact With l-Type Ca2+ Channels Accounts for First-Phase Insulin Secretion in Mouse β-Cells

Barg, S., Eliasson, L., Renström, E., & Rorsman, P. (2002) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 227

Rapid ATP‐Dependent Priming of Secretory Granules Precedes Ca 2+ ‐Induced Exocytosis in Mouse Pancreatic B‐Cells

Eliasson, L., Renström, E., Ding, W., Proks, P., & Rorsman, P. (1997) · The Journal of Physiology

Cellular transport and secretionPancreatic function and diabetes

Cited by 223

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

Barg, S., Galvanovskis, J., Göpel, S. O., Rorsman, P., & Eliasson, L. (2000) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 209

Novel aspects of the molecular mechanisms controlling insulin secretion

Eliasson, L., Abdulkader, F., Braun, M., Galvanovskis, J., Hoppa, M. B., & Rorsman, P. (2008) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 198

Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

Barg, S., Huang, P., Eliasson, L., Nelson, D. J., Obermüller, S., Rorsman, P., Thévenod, F., & Renström, E. (2001) · Journal of Cell Science

Pancreatic function and diabetesCellular transport and secretion

Cited by 194

Capacitance measurements of exocytosis in mouse pancreatic α‐, β‐ and δ‐cells within intact islets of Langerhans

Göpel, S., Zhang, Q., Eliasson, L., Ma, X., Galvanovskis, J., Kanno, T., Salehi, A., & Rorsman, P. (2004) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 160

Activation of Ca2+-Dependent K+ Channels Contributes to Rhythmic Firing of Action Potentials in Mouse Pancreatic β Cells

Göpel, S. O., Kanno, T., Barg, S., Eliasson, L., Galvanovskis, J., Renström, E., & Rorsman, P. (1999) · The Journal of General Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 137

Regulated Exocytosis of GABA-containing Synaptic-like Microvesicles in Pancreatic β-cells

Braun, M., Wendt, A., Birnir, B., Broman, J., Eliasson, L., Galvanovskis, J., Gromada, J., Mulder, H., & Rorsman, P. (2004) · The Journal of General Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 130

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes

Andersson, S. A., Olsson, A. H., Esguerra, J. L. S., Heimann, E., Ladenvall, C., Edlund, A., Salehi, A., Taneera, J., Degerman, E., Groop, L., et al. (2012) · Molecular and Cellular Endocrinology

Pancreatic function and diabetesCellular transport and secretion

Cited by 122

R-type Ca2+-channel-evoked CICR regulates glucose-induced somatostatin secretion

Zhang, Q., Bengtsson, M., Partridge, C., Salehi, A., Braun, M., Cox, R., Eliasson, L., Johnson, P. R., Renström, E., Schneider, T., et al. (2007) · Nature Cell Biology

Pancreatic function and diabetesIon channel regulation and function

Cited by 110

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans

Rorsman, P., Eliasson, L., Kanno, T., Zhang, Q., & Gopel, S. (2011) · Progress in Biophysics and Molecular Biology

Pancreatic function and diabetesIon channel regulation and function

Cited by 103

CaM kinase II‐dependent mobilization of secretory granules underlies acetylcholine‐induced stimulation of exocytosis in mouse pancreatic B‐cells

Gromada, J., Høy, M., Renström, E., Bokvist, K., Eliasson, L., Göpel, S., & Rorsman, P. (1999) · The Journal of Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 98

Long-Term Exposure to Glucose and Lipids Inhibits Glucose-Induced Insulin Secretion Downstream of Granule Fusion With Plasma Membrane

Olofsson, C. S., Collins, S., Bengtsson, M., Eliasson, L., Salehi, A., Shimomura, K., Tarasov, A., Holm, C., Ashcroft, F., & Rorsman, P. (2007) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 87