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International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

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The evolutionary history of 2,658 cancers

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Hypoxia signalling through mTOR and the unfolded protein response in cancer

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Patterns of somatic structural variation in human cancer genomes

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

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Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

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Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

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The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress

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Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

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“Translating” Tumor Hypoxia: Unfolded Protein Response (UPR)–Dependent and UPR-Independent Pathways

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Two phases of disulfide bond formation have differing requirements for oxygen

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A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients

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Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs

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Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

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MATE2 Expression Is Associated With Cancer Cell Response to Metformin

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Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Preclinical Models of Colorectal Cancer

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Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer

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