Hawkins, Philip N.

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

Adams, D., Gonzalez-Duarte, A., O’Riordan, W. D., Yang, C.-C., Ueda, M., Kristen, A. V., Tournev, I., Schmidt, H. H., Coelho, T., Berk, J. L., et al. (2018) · New England Journal of Medicine

Amyloidosis: Diagnosis, Treatment, OutcomesAlzheimer's disease research and treatments

Cited by 3,047

NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder

Agostini, L., Martinon, F., Burns, K., McDermott, M. F., Hawkins, P. N., & Tschopp, J. (2004) · Immunity

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 1,768

Safety and efficacy of RNAi therapy for transthyretin amyloidosis

Coelho, T., Adams, D., Silva, A., Lozeron, P., Hawkins, P. N., Mant, T., Perez, J., Chiesa, J., Warrington, S., Tranter, E., et al. (2013) · New England Journal of Medicine

Amyloidosis: Diagnosis, Treatment, OutcomesRNA Interference and Gene Delivery

Cited by 971

Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome

Lachmann, H. J., Kone-Paut, I., Kuemmerle-Deschner, J. B., Leslie, K. S., Hachulla, E., Quartier, P., Gitton, X., Widmer, A., Patel, N., & Hawkins, P. N. (2009) · New England Journal of Medicine

Inflammasome and immune disordersAutoimmune and Inflammatory Disorders Research

Cited by 869

Targeting C-reactive protein for the treatment of cardiovascular disease.

Pepys, M. B., Hirschfield, G. M., Tennent, G. A., Ruth Gallimore, J., Kahan, M. C., Bellotti, V., Hawkins, P. N., Myers, R. M., Smith, M. D., Polara, A., et al. (2006) · Nature

Biomarkers in Disease MechanismsComplement system in diseases

Cited by 672

Interleukin-1–Receptor Antagonist in the Muckle–Wells Syndrome

Hawkins, P. N., Lachmann, H. J., & McDermott, M. F. (2003) · New England Journal of Medicine

Inflammasome and immune disordersImmunodeficiency and Autoimmune Disorders

Cited by 654

Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis

Pepys, M. B., Herbert, J., Hutchinson, W. L., Tennent, G. A., Lachmann, H. J., Gallimore, J. R., Lovat, L. B., Bartfai, T., Alanine, A., Hertel, C., et al. (2002) · Nature

Amyloidosis: Diagnosis, Treatment, OutcomesAlzheimer's disease research and treatments

Cited by 540

Human plasma fibrinogen is synthesized in the liver

Tennent, G. A., Brennan, S. O., Stangou, A. J., O'Grady, J., Hawkins, P. N., & Pepys, M. B. (2007) · Blood

Amyloidosis: Diagnosis, Treatment, OutcomesBlood properties and coagulation

Cited by 304

Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene

Botto, M., Hawkins, P. N., Bickerstaff, M. C. M., Herbert, J., Bygrave, A. E., Mcbride, A., Hutchinson, W. L., Tennent, G. A., Walportz, M. J., & Pepys, M. B. (1997) · Nature Medicine

Amyloidosis: Diagnosis, Treatment, OutcomesAlzheimer's disease research and treatments

Cited by 266

Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis

Richards, D. B., Cookson, L. M., Barton, S. V., Liefaard, L., Lane, T., Hutt, D. F., Ritter, J. M., Fontana, M., Moon, J. C., Gillmore, J. D., et al. (2018) · Science Translational Medicine

Amyloidosis: Diagnosis, Treatment, OutcomesPrion Diseases and Protein Misfolding

Cited by 136